Alternatived Products of [ 19293-62-0 ]
Product Details of [ 19293-62-0 ]
CAS No. : | 19293-62-0 |
MDL No. : | MFCD00191409 |
Formula : |
C15H17NO2
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | HROGQYMZWGPHIB-UHFFFAOYSA-N |
M.W : |
243.30
|
Pubchem ID : | 350042 |
Synonyms : |
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Safety of [ 19293-62-0 ]
Signal Word: | Warning |
Class: | N/A |
Precautionary Statements: | P305+P351+P338 |
UN#: | N/A |
Hazard Statements: | H315-H319 |
Packing Group: | N/A |
GHS Pictogram: |
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Application In Synthesis of [ 19293-62-0 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Upstream synthesis route of [ 19293-62-0 ]
- Downstream synthetic route of [ 19293-62-0 ]
- 1
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[ 19293-62-0 ]
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[ 111969-64-3 ]
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[ 91538-20-4 ]
- 2
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[ 7296-64-2 ]
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[ 6336-45-4 ]
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[ 19293-62-0 ]
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6-[bis-(4-methoxy-phenyl)-methyl]-amino}-oct-7-ene-1,2,3,4,5-pentaol
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
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With water In ethanol at 50℃; for 72h; |
|
- 3
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[ 453-17-8 ]
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[ 6336-45-4 ]
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[ 19293-62-0 ]
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3-[bis-(4-methoxy-phenyl)-methyl]-amino}-pent-4-ene-1,2-diol
[ No CAS ]
- 4
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[ 608-45-7 ]
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[ 6336-45-4 ]
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[ 19293-62-0 ]
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5-[bis-(4-methoxy-phenyl)-methyl]-amino}-hept-6-ene-1,2,3,4-tetraol
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
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With water In ethanol at 50℃; for 72h; |
|
- 5
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[ 7296-55-1 ]
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[ 6336-45-4 ]
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[ 19293-62-0 ]
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5-[bis-(4-methoxy-phenyl)-methyl]-amino}-hept-6-ene-1,2,3,4-tetraol
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
With water In ethanol at 50℃; for 72h; |
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- 6
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[ 728-87-0 ]
-
[ 19293-62-0 ]
Yield | Reaction Conditions | Operation in experiment |
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Multi-step reaction with 2 steps
1: Et3N / tetrahydrofuran / -78 - -20 °C
2: 15.59 g / liq. ammonia / tetrahydrofuran / -78 - 25 °C |
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Multi-step reaction with 2 steps
1: triethylamine / CH2Cl2 / 0.5 h / -50 - -20 °C
2: NH3 / tetrahydrofuran; CH2Cl2 / -50 °C |
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Multi-step reaction with 2 steps
1: 98 percent / hydrogen chloride / diethyl ether
2: 100 percent / ammonia gas / CHCl3 / 2 h |
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Multi-step reaction with 2 steps
1: 99 percent / SOCl2
2: 90 percent / liq. NH3 |
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Multi-step reaction with 2 steps
1: 12.8 g / anhyd.HCl / diethyl ether
2: liq. NH3 / 6 h |
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Multi-step reaction with 2 steps
1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 1 h / 0 - 25 °C / Inert atmosphere; Darkness
2: hydrazine hydrate / methanol; acetic acid / 4 h / Reflux; Inert atmosphere; Darkness |
|
Reference:
[1]Lu, Zhenjie; Zhang, Yu; Wulff, William D.
[Journal of the American Chemical Society, 2007, vol. 129, # 22, p. 7185 - 7194]
[2]Dugat; Just; Sahoo
[Canadian Journal of Chemistry, 1987, vol. 65, # 1, p. 88 - 93]
[3]Acheson; Bite; Kemp
[Journal of Medicinal Chemistry, 1981, vol. 24, # 11, p. 1300 - 1304]
[4]Hutchins, Robert O.; Su, Wei-Yang; Sivakumar, Ramachandran; Cistone, Frank; Stercho, Yuriy P.
[Journal of Organic Chemistry, 1983, vol. 48, # 20, p. 3412 - 3422]
[5]Greenlee, W. J.
[Journal of Organic Chemistry, 1984, vol. 49, # 14, p. 2632 - 2634]
[6]Bariamis, Stavros E.; Magoulas, George E.; Grafanaki, Katerina; Pontiki, Eleni; Tsegenidis, Theodore; Athanassopoulos, Constantinos M.; Maroulis, George; Papaioannou, Dionissios; Hadjipavlou-Litina, Dimitra
[Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 22, p. 7251 - 7263]
- 7
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[ 2689-69-2 ]
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[ 19293-62-0 ]
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[ 149622-18-4 ]
Yield | Reaction Conditions | Operation in experiment |
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With toluene-4-sulfonic acid; In water; toluene; benzene; |
Example VI Methyl 3-N-(4,4'-dimethoxybenzhydryl)amino-4,5-dihydro-thiophene-2-carboxylate STR26 A solution of 4.5 g (28.0 nunol) of methyl tetrahydrothiophene-3-one-2-carboxylate, 6.9 g (28 mmol) of 4,4'-dimethoxy-benzhydrylamine and 0.1 g of p-toluenesulphonic acid are heated under reflux in a water separator in 50 ml of benzene for 24 h. The mixture is then diluted with 40 ml of toluene, and washed with 40 ml of 1% strength aqueous NaHCO3 solution and twice with 30 ml of water in each case. The organic phase is dried over Na2 SO4 and the solvent is stripped off in vacuo. The residue is chromatographed on silica gel (ether/petroleum ether =1:2) Yield: 7.58 g (70% of theory). C21 H23 NO4 S(385.4). Rf =0.42 (ether: petroleum ether =1:2). |
- 8
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[ 1187992-93-3 ]
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[ 19293-62-0 ]
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[ 1187990-87-9 ]
Yield | Reaction Conditions | Operation in experiment |
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|
To a suspension of Intermediate 8 (14.94 g, 68.5 mmol) in DMF (225 mL) was added TEA (18.98 mL, 137 mmol) and CDI (11.10 g, 68.5 mmol). The reaction was heated at 120 C. for 1 h followed by the addition of 4,4'-dimethoxybenzhydrlamine (14.99 g, 61.6 mmol). The reaction was heated at 115 C. for 1 h, diluted with CHCl3, washed with aq. HCl (1 M), deionized H2O and concentrated. The material was crystallized from the residue using EtOH to afford the title compound. HPLC/MS: 444.18 (M+1); Rt=2.90 min. |
- 9
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[ 832697-40-2 ]
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[ 19293-62-0 ]
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[ 298-12-4 ]
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C26H30N2O6
[ No CAS ]
- 10
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[ 177734-82-6 ]
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[ 19293-62-0 ]
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[ 298-12-4 ]
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C21H20ClNO4S
[ No CAS ]