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Chemical Structure| 2067-33-6 Chemical Structure| 2067-33-6
Chemical Structure| 2067-33-6

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Product Details of 5-Bromovaleric acid

CAS No. :2067-33-6
Formula : C5H9BrO2
M.W : 181.03
SMILES Code : O=C(O)CCCCBr
MDL No. :MFCD00004414
InChI Key :WNXNUPJZWYOKMW-UHFFFAOYSA-N
Pubchem ID :16368

Safety of 5-Bromovaleric acid

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 5-Bromovaleric acid

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2067-33-6 ]

[ 2067-33-6 ] Synthesis Path-Downstream   1~7

  • 1
  • [ 2067-33-6 ]
  • [ 84500-41-4 ]
  • [ 1126489-56-2 ]
  • 2
  • [ 2067-33-6 ]
  • [ 545445-44-1 ]
  • 3
  • [ 67-56-1 ]
  • [ 2067-33-6 ]
  • [ 50995-48-7 ]
YieldReaction ConditionsOperation in experiment
Step 1 (Synthesis of 131-2) (0671) In a dry three-necked flask, compound 131-1 (18.00 g, 99.43 mmol, 1.0 eq.) was dissolved in thionyl chloride (59.15 g, 497.15 mmol, 5.0 eq.), and the mixture was warmed to 80° C., stirred for 1 hour, and then cooled to 50° C. Br2 (31.78 g, 198.8 mmol, 2.0 eq.) was added into the reaction mixture, at 50° C. was stirred the mixture for 40 hours. The reaction mixture was cooled to 30° C., and anhydrous methanol (40 mL) was carefully added, then the mixture was heated up 50° C. and continued stirring for 1 hour. The reaction mixture was cooled to 25° C., and concentrated under reduced pressure. The residue was dissolved with EtOAc, and washed with saturated sodium sulfite. The organic phase was washed with saturated brine, dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure to obtain 20 g crude product as yellow oil. The crude product was directly used in the next reaction. (0672) 1H NMR (400 MHz, CDCl3) delta: 4.28 (q, J=6.0 Hz, 2H), 3.80 (s, 3H), 3.43 (t, J=6.0 Hz, 2H), 1.95-2.26 (m, 3H)
  • 4
  • [ 2067-33-6 ]
  • [ 551-11-1 ]
  • 5
  • [ 2067-33-6 ]
  • [ 78430-91-8 ]
  • C17H21N2O2(1+)*Br(1-) [ No CAS ]
  • 6
  • [ 21252-69-7 ]
  • [ 2067-33-6 ]
  • C16H29N2O2(1+)*Br(1-) [ No CAS ]
  • 7
  • [ 2067-33-6 ]
  • [ 2848-01-3 ]
  • C20H24O4P(1+)*Br(1-) [ No CAS ]
 

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