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Chemical Structure| 2103-94-8 Chemical Structure| 2103-94-8

Structure of 2103-94-8

Chemical Structure| 2103-94-8

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Product Details of [ 2103-94-8 ]

CAS No. :2103-94-8
Formula : C9H7BrN2S
M.W : 255.13
SMILES Code : NC1=NC(=CS1)C1=CC=C(Br)C=C1
MDL No. :MFCD00051953
InChI Key :ZBRNKOLWXWMLTA-UHFFFAOYSA-N
Pubchem ID :620683

Safety of [ 2103-94-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 2103-94-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2103-94-8 ]

[ 2103-94-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 2103-94-8 ]
  • [ 526-08-9 ]
  • [ 97854-97-2 ]
  • 2
  • [ 1878-91-7 ]
  • [ 2103-94-8 ]
  • 2-(4-bromophenoxy)-N-(4-(4-bromophenyl) thiazol-2-yl)acetamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
General procedure: Phenoxyacetic acids (4a-j, 2mmol) in dry DCM (20ml) was stirred at 25-30C, and then lutidine (3mmol) was added, followed by the addition of substituted amino-4-phenyl-1,3-thiazoles (2mmol). The reaction mixture was stirred at the same temperature for 30min, then cooled to 0-5C and TBTU (2mmol) was added over a period of 30min maintaining the temperature below 5C. The reaction mass was stirred overnight and monitored by TLC using chloroform: methanol (9:1) as the mobile phase. The purity of the compounds was determined using high performance liquid chromatography (HPLC) by reversed phase agilent zorbax SB-C18 column method, with methanol (50%): acetonitrile (30%): water (20%) as mobile phase. The solvent was evaporated at reduced pressure, quenched by the addition of crushed ice and the obtained solid was filtered, dried and recrystallized from ethanol to afford compounds 8a-ab in good yield [supplementary files].
 

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Related Parent Nucleus of
[ 2103-94-8 ]

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