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[ CAS No. 2176-63-8 ] {[proInfo.proName]}

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Cat. No.: {[proInfo.prAm]}
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There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
3d Animation Molecule Structure of 2176-63-8
Chemical Structure| 2176-63-8
Chemical Structure| 2176-63-8
Structure of 2176-63-8 * Storage: {[proInfo.prStorage]}
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Alternatived Products of [ 2176-63-8 ]

Product Details of [ 2176-63-8 ]

CAS No. :2176-63-8 MDL No. :MFCD00183239
Formula : C5H2Cl4N2 Boiling Point : -
Linear Structure Formula :- InChI Key :CPLQYBDXWJHBST-UHFFFAOYSA-N
M.W : 231.89 Pubchem ID :1556893
Synonyms :

Calculated chemistry of [ 2176-63-8 ]

Physicochemical Properties

Num. heavy atoms : 11
Num. arom. heavy atoms : 6
Fraction Csp3 : 0.0
Num. rotatable bonds : 0
Num. H-bond acceptors : 1.0
Num. H-bond donors : 1.0
Molar Refractivity : 48.68
TPSA : 38.91 Ų

Pharmacokinetics

GI absorption : High
BBB permeant : Yes
P-gp substrate : No
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -6.14 cm/s

Lipophilicity

Log Po/w (iLOGP) : 1.82
Log Po/w (XLOGP3) : 2.22
Log Po/w (WLOGP) : 3.29
Log Po/w (MLOGP) : 2.21
Log Po/w (SILICOS-IT) : 3.31
Consensus Log Po/w : 2.57

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 0.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -3.08
Solubility : 0.193 mg/ml ; 0.000832 mol/l
Class : Soluble
Log S (Ali) : -2.67
Solubility : 0.493 mg/ml ; 0.00213 mol/l
Class : Soluble
Log S (SILICOS-IT) : -4.14
Solubility : 0.0169 mg/ml ; 0.0000728 mol/l
Class : Moderately soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 1.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 1.96

Safety of [ 2176-63-8 ]

Signal Word:Danger Class:6.1
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501 UN#:2811
Hazard Statements:H301-H311-H331 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 2176-63-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2176-63-8 ]

[ 2176-63-8 ] Synthesis Path-Downstream   1~32

  • 1
  • [ 17325-31-4 ]
  • [ 2176-63-8 ]
  • 4
  • [ 2176-63-8 ]
  • [ 64-17-5 ]
  • [ 141-52-6 ]
  • [ 35622-88-9 ]
  • 5
  • [ 2176-63-8 ]
  • [ 141-52-6 ]
  • 6-ethoxy-4-amino-3,5-dichloro-pyridin-2-ol [ No CAS ]
  • 2,6-diethoxy-3,5-dichloro-[4]pyridylamine [ No CAS ]
  • 6
  • [ 2176-63-8 ]
  • [ 141-52-6 ]
  • [ 35622-88-9 ]
  • 7
  • [ 2176-63-8 ]
  • 3,5,6-trichloro-pyridine-2,4-diyldiamine [ No CAS ]
  • 8
  • [ 28443-69-8 ]
  • [ 2176-63-8 ]
  • 11
  • [ 2176-63-8 ]
  • [ 2007-97-8 ]
  • (2-Chloro-2λ5-benzo[1,3,2]dioxaphosphol-2-ylidene)-(2,3,5,6-tetrachloro-pyridin-4-yl)-amine [ No CAS ]
  • C22H8Cl10N4O4P2 [ No CAS ]
  • 17
  • [ 50524-37-3 ]
  • [ 874483-75-7 ]
  • [ 2176-63-8 ]
  • 18
  • 3.5.6-trichloro-4-amino-2-oxy-pyridine [ No CAS ]
  • [ 2176-63-8 ]
  • 19
  • [ 2176-62-7 ]
  • [ 7664-41-7 ]
  • [ 2176-63-8 ]
  • [ 51501-52-1 ]
  • 20
  • [ 107-10-8 ]
  • 1-(4-dimethylamino)-[2,3,5,6-tetrachloro-pyridin-4-yl]pyridinium chloride [ No CAS ]
  • 3,5,6-trichloro-N2-propyl-pyridine-2,4-diamine [ No CAS ]
  • 3,5,6-trichloro-N2,N4-dipropyl-pyridine-2,4-diamine [ No CAS ]
  • [ 2176-63-8 ]
  • 3,5,6-trichloro-pyridine-2,4-diyldiamine [ No CAS ]
  • 21
  • [ 75-31-0 ]
  • 1-(4-dimethylamino)-[2,3,5,6-tetrachloro-pyridin-4-yl]pyridinium chloride [ No CAS ]
  • isopropyl-(2,3,5,6-tetrachloro-pyridin-4-yl)-amine [ No CAS ]
  • 3,5,6-trichloro-N2-isopropyl-pyridine-2,4-diamine [ No CAS ]
  • [ 2176-63-8 ]
  • 3,5,6-trichloro-pyridine-2,4-diyldiamine [ No CAS ]
  • 31
  • [ 2176-63-8 ]
  • 6-ethoxy-4-amino-3,5-dichloro-pyridin-2-ol [ No CAS ]
  • 32
  • [ 2808-86-8 ]
  • [ 2176-63-8 ]
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