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Chemistry
Heterocyclic Building Blocks
Pyridines
trichloropyridine
2,3,5-Trichloropyridin-4-amine
Chemistry
Heterocyclic Building Blocks
Organic Building Blocks
Pyridines
Amines Chlorides
trichloropyridine
2,3,5-trichloropyridine

[ CAS No. 28443-69-8 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
3d Animation Molecule Structure of 28443-69-8
Chemical Structure| 28443-69-8
Chemical Structure| 28443-69-8
Structure of 28443-69-8 * Storage: {[proInfo.prStorage]}
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Quality Control of [ 28443-69-8 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 28443-69-8 ]

SDS Specification
Alternatived Products of [ 28443-69-8 ]

Product Details of [ 28443-69-8 ]

CAS No. :28443-69-8 MDL No. :MFCD00153908
Formula : C5H3Cl3N2 Boiling Point : -
Linear Structure Formula :- InChI Key :YYJDUYUWQJWYNA-UHFFFAOYSA-N
M.W : 197.45 Pubchem ID :728676
Synonyms :

Calculated chemistry of [ 28443-69-8 ]

Physicochemical Properties

Num. heavy atoms : 10
Num. arom. heavy atoms : 6
Fraction Csp3 : 0.0
Num. rotatable bonds : 0
Num. H-bond acceptors : 1.0
Num. H-bond donors : 1.0
Molar Refractivity : 43.67
TPSA : 38.91 Ų

Pharmacokinetics

GI absorption : High
BBB permeant : Yes
P-gp substrate : No
CYP1A2 inhibitor : Yes
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -5.81 cm/s

Lipophilicity

Log Po/w (iLOGP) : 1.67
Log Po/w (XLOGP3) : 2.39
Log Po/w (WLOGP) : 2.63
Log Po/w (MLOGP) : 1.62
Log Po/w (SILICOS-IT) : 2.64
Consensus Log Po/w : 2.19

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 1.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -3.01
Solubility : 0.191 mg/ml ; 0.000969 mol/l
Class : Soluble
Log S (Ali) : -2.85
Solubility : 0.28 mg/ml ; 0.00142 mol/l
Class : Soluble
Log S (SILICOS-IT) : -3.52
Solubility : 0.0599 mg/ml ; 0.000303 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 1.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 1.87

Safety of [ 28443-69-8 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P280-P305+P351+P338 UN#:N/A
Hazard Statements:H302+H312+H332-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 28443-69-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 28443-69-8 ]
  • Downstream synthetic route of [ 28443-69-8 ]

[ 28443-69-8 ] Synthesis Path-Upstream   1~19

  • 1
  • [ 94-75-7 ]
  • [ 1918-02-1 ]
  • [ 100047-36-7 ]
  • [ 695-99-8 ]
  • [ 28443-69-8 ]
  • [ 615-67-8 ]
  • [ 120-83-2 ]
Reference： [1] Photochemical and Photobiological Sciences, 2015, vol. 14, # 3, p. 536 - 542
  • 2
  • [ 5005-62-9 ]
  • [ 28443-69-8 ]
  • [ 1918-02-1 ]
Reference： [1] J. Appl. Chem. USSR (Engl. Transl.), 1992, vol. 65, # 5, p. 824 - 830[2] Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1992, vol. 65, # 5, p. 1008 - 1016
[3] J. Appl. Chem. USSR (Engl. Transl.), 1992, vol. 65, # 5, p. 824 - 830[4] Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1992, vol. 65, # 5, p. 1008 - 1016
  • 3
  • [ 2808-86-8 ]
  • [ 28443-69-8 ]
Reference： [1] Journal of the Chemical Society, 1900, vol. 77, p. 3
[2] Journal of the Chemical Society, 1900, vol. 77, p. 3
[3] J. Appl. Chem. USSR (Engl. Transl.), 1992, vol. 65, # 5, p. 824 - 830[4] Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1992, vol. 65, # 5, p. 1008 - 1016
  • 4
  • [ 405230-82-2 ]
  • [ 28443-69-8 ]
Reference： [1] Recueil des Travaux Chimiques des Pays-Bas, 1950, vol. 69, p. 673,690
  • 5
  • [ 184416-83-9 ]
  • [ 28443-69-8 ]
Reference： [1] Recueil des Travaux Chimiques des Pays-Bas, 1950, vol. 69, p. 673,690
  • 6
  • [ 626-03-9 ]
  • [ 28443-69-8 ]
Reference： [1] Recueil des Travaux Chimiques des Pays-Bas, 1950, vol. 69, p. 673,690
  • 7
  • [ 55934-01-5 ]
  • [ 28443-69-8 ]
Reference： [1] Recueil des Travaux Chimiques des Pays-Bas, 1950, vol. 69, p. 673,690
  • 8
  • [ 7321-93-9 ]
  • [ 28443-69-8 ]
Reference： [1] Recueil des Travaux Chimiques des Pays-Bas, 1950, vol. 69, p. 673,690
  • 9
  • [ 103792-81-0 ]
  • [ 28443-69-8 ]
Reference： [1] Recueil des Travaux Chimiques des Pays-Bas, 1950, vol. 69, p. 673,690
  • 10
  • [ 96245-97-5 ]
  • [ 28443-69-8 ]
Reference： [1] Recueil des Travaux Chimiques des Pays-Bas, 1950, vol. 69, p. 673,690
  • 11
  • [ 55934-02-6 ]
  • [ 28443-69-8 ]
Reference： [1] Recueil des Travaux Chimiques des Pays-Bas, 1950, vol. 69, p. 673,690
  • 12
  • [ 166526-03-0 ]
  • [ 28443-69-8 ]
Reference： [1] Recueil des Travaux Chimiques des Pays-Bas, 1950, vol. 69, p. 673,690
  • 13
  • [ 73027-79-9 ]
  • [ 28443-69-8 ]
Reference： [1] Recueil des Travaux Chimiques des Pays-Bas, 1950, vol. 69, p. 673,690
  • 14
  • [ 40296-46-6 ]
  • [ 28443-69-8 ]
Reference： [1] Recueil des Travaux Chimiques des Pays-Bas, 1950, vol. 69, p. 673,690
  • 15
  • [ 6975-44-6 ]
  • [ 28443-69-8 ]
Reference： [1] Recueil des Travaux Chimiques des Pays-Bas, 1950, vol. 69, p. 673,690
  • 16
  • [ 94-75-7 ]
  • [ 1918-02-1 ]
  • [ 100047-36-7 ]
  • [ 695-99-8 ]
  • [ 28443-69-8 ]
  • [ 615-67-8 ]
  • [ 120-83-2 ]
Reference： [1] Photochemical and Photobiological Sciences, 2015, vol. 14, # 3, p. 536 - 542
  • 17
  • [ 2808-86-8 ]
  • [ 7664-41-7 ]
  • [ 28443-69-8 ]
Reference： [1] Journal of the Chemical Society, 1900, vol. 77, p. 3
  • 18
  • [ 28443-69-8 ]
  • [ 1970-40-7 ]
Reference： [1] Journal of the Chemical Society, 1903, vol. 83, p. 400
  • 19
  • [ 94-75-7 ]
  • [ 1918-02-1 ]
  • [ 100047-36-7 ]
  • [ 695-99-8 ]
  • [ 28443-69-8 ]
  • [ 615-67-8 ]
  • [ 120-83-2 ]
Reference： [1] Photochemical and Photobiological Sciences, 2015, vol. 14, # 3, p. 536 - 542

Tags: 28443-69-8 synthesis path| 28443-69-8 SDS| 28443-69-8 COA| 28443-69-8 purity| 28443-69-8 application| 28443-69-8 NMR| 28443-69-8 COA| 28443-69-8 structure

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Chemistry
Heterocyclic Building Blocks
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trichloropyridine
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Chlorides
trichloropyridine
Chemistry
Heterocyclic Building Blocks
Pyridines
2,3,5-trichloropyridine
Chemistry
Organic Building Blocks
Chlorides
2,3,5-trichloropyridine
Chemistry
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