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Chemical Structure| 29568-78-3 Chemical Structure| 29568-78-3

Structure of 29568-78-3

Chemical Structure| 29568-78-3

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Product Details of [ 29568-78-3 ]

CAS No. :29568-78-3
Formula : C9H8ClNO5
M.W : 245.62
SMILES Code : O=C(Cl)C1=CC(OC)=C(OC)C=C1[N+]([O-])=O
MDL No. :MFCD12546351

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Application In Synthesis of [ 29568-78-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 29568-78-3 ]

[ 29568-78-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 41764-74-3 ]
  • [ 29568-78-3 ]
  • [ 1180205-60-0 ]
YieldReaction ConditionsOperation in experiment
32% To 1.00 g (4.07 mmol) of acid chloride 68 in 25 mL of DCM at 0 C was added 5 mL of pyridine. The mixture was stirred 3 min, and 0.76 g (3.87 mmol) of known hydrazide 69 was added at once. The mixture was gradually allowed to warm to 21-23 C and stirred at this temperature for 16 h. The mixture was concentrated, treated with 10 mL of ethanol, warmed to reflux, and diluted with 30 mL of water. After returning the mixture to reflux, ethanol was added gradually until a solution formed. The solution was allowed to cool, and the precipitated light yellow solid was collected and dried to give 0.498 g (1.24 mmol, 32% yield) of 70.1H NMR (CDCI3 and MeOD, δ) 7.54 (s, 1H), 7.45 (dd, / = 2.2, 8.4 Hz, 1H), 7.39 (d, / = 1.8 Hz), 7.16 (s, 1H), 6.82 (d, / = 8.4 Hz, 1H), 3.98-3.73 (overlapping singlets + residual H20 peak, 12H).
 

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