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Chemical Structure| 3471-13-4 Chemical Structure| 3471-13-4

Structure of 3471-13-4

Chemical Structure| 3471-13-4

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Product Details of [ 3471-13-4 ]

CAS No. :3471-13-4
Formula : C8H12O2
M.W : 140.18
SMILES Code : CC(C1)(C)CC(O)=CC1=O

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Application In Synthesis of [ 3471-13-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3471-13-4 ]

[ 3471-13-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 6374-91-0 ]
  • [ 3471-13-4 ]
  • [ 109-77-3 ]
  • 2-amino-5',7'-dibromo-7,7-dimethyl-2',5-dioxo-5,6,7,8-tetrahydrospiro[chromene-4,3'-indoline]-3-carbonitrile [ No CAS ]
YieldReaction ConditionsOperation in experiment
89% With 2-amino-2-hydroxymethyl-1,3-propanediol; In ethanol; at 20℃; for 3.5h; General procedure: To a well-stirred solution of isatin and malononitrile(1 mmol each) in ethanol (95%, 4 mL) was added dimedone,4-hydroxycoumarin, 4-hydroxy-N-methylquinolin-2-one,or 2-methyl-pyrazol-2-one [generated in situ from ethylacetoacetate and hydrazine hydrate, 1 mmol each]. To thissolution was added THAM (30 mol %) and stirring wascontinued at ambient temperature. Upon completion of thereaction (TLC), water (5 mL) was added and stirring wascontinued for 10 min more. Resultant solid product wasfiltered, washed repeatedly with water, and dried. The dried solid was washed thrice with hexaneechloroformmixture (1:1, v/v) and dried again. Resultant product didnot require any further purification.
 

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