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Chemical Structure| 38775-38-1 Chemical Structure| 38775-38-1

Structure of 38775-38-1

Chemical Structure| 38775-38-1

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Product Details of [ 38775-38-1 ]

CAS No. :38775-38-1
Formula : C16H33ClO2S
M.W : 324.95
SMILES Code : CCCCCCCCCCCCCCCCS(=O)(Cl)=O
MDL No. :MFCD00007459
InChI Key :YOSVFFVBSPQTTP-UHFFFAOYSA-N
Pubchem ID :96923

Safety of [ 38775-38-1 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P260-P264-P280-P305+P351+P338-P405-P501
Class:8
UN#:3261
Packing Group:

Application In Synthesis of [ 38775-38-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 38775-38-1 ]

[ 38775-38-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 288-32-4 ]
  • [ 38775-38-1 ]
  • [ 5131-60-2 ]
  • [ 63134-12-3 ]
YieldReaction ConditionsOperation in experiment
72% In n-heptane; water; ethyl acetate; toluene; EXAMPLE 1 A room temperature solution of 1-chloro-2,4-diaminobenzene (1.43 g, 10 mmol), 1-hexadecanesulfonyl chloride (3.24 g, 10 mmol), imidazole (0.68 g, 10 mmol) and toluene (20 mL) was stirred for 1 hr. Isopropyl alcohol (20 mL) was added and the reaction mixture was heated at 60° C. for 2 hours. Analysis by thin layer chromatography (tlc) (40percent ethyl acetate and 60percent heptane) indicated incomplete acylation and additional 1-hexadecanesulfonyl chloride (0.7 g, 2 mmol) was added and the reaction mixture was stirred at 60°-62° C. for an additional hour, at which time the reaction appeared to be complete by tlc analysis. The reaction solution was treated with hot water (50 mL) and the layers separated. The toluene layer was further washed twice with 50 mL of hot water. Heptane (20 mL) was added to the recovered toluene layer to precipitate the product, N-(3-amino-4-chlorophenyl)-1-hexadecanesulfonamide, which was isolated by cooling the mixture to about 0° C. and collecting the product by vacuum filtration. After being washed with cold heptane, the product was dried (yield=3.12 g, 72percent of the theoretical yield) and it melted at 103°-104° C. No impurities were observed by H1 NMR analysis.
 

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