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Chemical Structure| 482308-06-5 Chemical Structure| 482308-06-5

Structure of 482308-06-5

Chemical Structure| 482308-06-5

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Product Details of [ 482308-06-5 ]

CAS No. :482308-06-5
Formula : C11H16N2O2
M.W : 208.26
SMILES Code : NC1=CC=C(N2CCOCC2)C(OC)=C1
MDL No. :MFCD09755872

Safety of [ 482308-06-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 482308-06-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 482308-06-5 ]

[ 482308-06-5 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 482308-06-5 ]
  • [ 98556-31-1 ]
  • (6-iodo-quinazolin-4-yl)-(3-methoxy-4-morpholin-4-yl-phenyl)-amine [ No CAS ]
YieldReaction ConditionsOperation in experiment
88% In acetonitrile;Heating / reflux; Step 3: Heating of 3-methoxy-4-morpholin-4-yl-phenylamine (136mg ) and 4- chloro-6-iodoquinazoline (186mg) in acetonitrile (10ml) at reflux overnight gave, on cooling, a precipitate that was isolated by filtration, washed with water then slurried with IN NaOH and washed with further water and dried. This gave the title compound (263mg, 88%) 6 (DMSO) 11.01 (1H, br s); 9.20 (lH, s); 8.83 (lH, s); 8.29 (1H, d, J8.85Hz); 7.67 (1H, d, J8.85Hz) ; 7.40 (2H, m) ; 6.98 (lH, d, J8.85Hz) ; 8.83 (3H, s) ; 3.76 (4H, m); 3.01 (4H, m). , LC-MS rt 2.74, m/z E+463
  • 2
  • [ 454-16-0 ]
  • [ 482308-06-5 ]
 

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