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Chemical Structure| 4946-22-9 Chemical Structure| 4946-22-9

Structure of 4946-22-9

Chemical Structure| 4946-22-9

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Product Details of [ 4946-22-9 ]

CAS No. :4946-22-9
Formula : C8H11NS
M.W : 153.25
SMILES Code : SC1=CC=C(N(C)C)C=C1
MDL No. :MFCD01658123
InChI Key :PQSBRHXGVPVYFJ-UHFFFAOYSA-N
Pubchem ID :21061

Safety of [ 4946-22-9 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301+H311+H331-H315-H319
Precautionary Statements:P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P361+P364-P332+P313-P301+P310+P330-P302+P352+P312-P304+P340+P311-P403+P233-P405
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 4946-22-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 4946-22-9 ]

[ 4946-22-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 4946-22-9 ]
  • [ 41602-56-6 ]
  • [ 109-77-3 ]
  • 2,4-diamino-8-(dimethylamino)-5-((4-(dimethylamino)phenyl)thio)-5H-chromeno[2,3-b]pyridine-3-carbonitrile [ No CAS ]
YieldReaction ConditionsOperation in experiment
88% With triethylamine; In ethanol; for 4h;Reflux; General procedure: An amount of malonitrile (2 mmol), desired thiophenol (1 mmol) and triethyl amine (0.1 mmol) were added in a solution of 4-dimethylamino-salisaldehyde (1 mmol) in 7 mL EtOH. The resulting mixture was allowed to reflux over 4 h, at which point the product precipitates out of the solution. The resulting precipitate was filtered off and dried under vacuum. The residue was then dissolved in 3 mL DMF. The insoluble particles were filtered off. A volume of 4 mL H2O was then poured into the resulting filtrate, leading to the precipitation of the pure product out of the solution. The precipitates were filtered off and dried under vacuum, leading to the pure 5H-substituted-thiochromenopyridines (1g-1i, 89%-91%) as light pinkish solids.
 

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