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Chemical Structure| 59578-63-1 Chemical Structure| 59578-63-1

Structure of 59578-63-1

Chemical Structure| 59578-63-1

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Product Details of [ 59578-63-1 ]

CAS No. :59578-63-1
Formula : C11H17NO
M.W : 179.26
SMILES Code : OCCCCNCC1=CC=CC=C1
MDL No. :MFCD00191609
InChI Key :SNRCGOVPZJPRQZ-UHFFFAOYSA-N
Pubchem ID :1790018

Safety of [ 59578-63-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Application In Synthesis of [ 59578-63-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 59578-63-1 ]

[ 59578-63-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 59578-63-1 ]
  • [ 2905-56-8 ]
YieldReaction ConditionsOperation in experiment
63% With iodine; triethylamine; triethyl phosphite; In dichloromethane; at -78 - 20℃;Inert atmosphere; General procedure: Under an atmosphere of argon the amino alcohol/diol (rac-)12 (1.0 equiv, 1-2 mmol) was dissolved in NEt3 (6.0 equiv) and dry CH2Cl2 (NEt3/CH2Cl2 1:2), the mixture was cooled to -78 C in an acetone/dryice bath and treated with P(OEt)3 (1.4 equiv). Subsequently, iodine (1.2 equiv) was added in oneportion and the mixture was stirred at -78 C until complete dissolution of iodine (2.5-5 h). Then the cooling bath was removed and the clear reaction solution was allowed to stir at ambient temperature for 0.5 h [25].
 

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