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Chemical Structure| 6725-74-2 Chemical Structure| 6725-74-2

Structure of 6725-74-2

Chemical Structure| 6725-74-2

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Product Details of [ 6725-74-2 ]

CAS No. :6725-74-2
Formula : C11H11Br
M.W : 223.11
SMILES Code : BrC1(CCC=C1)C1=CC=CC=C1
MDL No. :MFCD16295096

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Application In Synthesis of [ 6725-74-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6725-74-2 ]

[ 6725-74-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 212386-71-5 ]
  • [ 6725-74-2 ]
  • C19H18F2O [ No CAS ]
YieldReaction ConditionsOperation in experiment
80% With tetrakis(triphenylphosphine) palladium(0); sodium carbonate; In ethanol; water; toluene; for 5h;Inert atmosphere; Reflux; Under a nitrogen atmosphere, 11.1 g (0.05 mol) 4 - cyclopentenyl phenyl bromide (3-a), 10.1 g (0.05 mol) 2,3-di-fluoro-4-ethoxy phenylboronic acid, 6.4 g (0.06 mol) of sodium carbonate, 50 ml toluene, 50 ml ethanol, 50 ml water and 0.3 g of tetrakis (triphenylphosphine) palladium and 250 ml filled with the three-necked flask, and was heated to reflux for 5 hours with stirring. It was added to 100 ml of water, and the organic phase was separated. The aqueous phase was extracted with 20 ml toluene (1x). The organic phases were combined, washed twice and evaporated with water to remove the solvent completely, and was dissolved in petroleum ether and purified by silica gel column chromatography and then recrystallized from petroleum ether, 12 g of white crystals (4-a) was obtained. Yield: 80%.
  • 2
  • [ 212386-71-5 ]
  • [ 6725-74-2 ]
  • C19H20F2O [ No CAS ]
 

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