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Chemical Structure| 707-60-8 Chemical Structure| 707-60-8

Structure of 707-60-8

Chemical Structure| 707-60-8

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Product Details of [ 707-60-8 ]

CAS No. :707-60-8
Formula : C8H10BrNO2S
M.W : 264.14
SMILES Code : CN(C)S(=O)(=O)C1=CC=C(Br)C=C1
MDL No. :MFCD00017834
InChI Key :NQAUNPZZVCXYEJ-UHFFFAOYSA-N
Pubchem ID :12818

Safety of [ 707-60-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 707-60-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 707-60-8 ]

[ 707-60-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 707-60-8 ]
  • [ 80500-27-2 ]
  • [ 1303573-58-1 ]
YieldReaction ConditionsOperation in experiment
96% With tetrabutylammomium bromide; palladium diacetate; sodium carbonate; In water; at 150℃; for 0.0833333h;Microwave irradiation; Commercially available 4-bromo-N,Ndimethylbenzenesulfonamide 13a (664 mg, 2.51 mmol) was placed in a vial together with commercially available 4-methyl-3-nitrobenzeneboronic acid (500 mg, 2.77 mmol), sodium carbonate (798 mg, 7.53 mmol), Pd(OAc)2 (2.3 mg, 0.010 mmol), tetrabutylammonium bromide (809 mg, 2.51 mmol) and water (5 mL). The vial was sealed and heated under stirring at 150 C in a microwave reactor for 5 min. The reaction mixture was then diluted with water and repeatedly extracted with EtOAc. The combined organic phase was dried over anhydrous sodium sulphate and evaporated to afford a crude residue that was purified by column chromatography over silica gel using n-hexane/EtOAc mixture as the eluent.
  • 2
  • [ 1709-59-7 ]
  • [ 707-60-8 ]
 

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