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Chemical Structure| 7391-28-8 Chemical Structure| 7391-28-8

Structure of 7391-28-8

Chemical Structure| 7391-28-8

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Product Details of [ 7391-28-8 ]

CAS No. :7391-28-8
Formula : C10H9NO
M.W : 159.18
SMILES Code : N#CCC(C1=CC=C(C)C=C1)=O
MDL No. :MFCD00067895
InChI Key :AIECDYDQPCANJK-UHFFFAOYSA-N
Pubchem ID :522513

Safety of [ 7391-28-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P233-P260-P261-P264-P270-P271-P280-P301+P312-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P330-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501

Application In Synthesis of [ 7391-28-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 7391-28-8 ]

[ 7391-28-8 ] Synthesis Path-Downstream   1~5

  • 1
  • [ 33906-30-8 ]
  • [ 7391-28-8 ]
  • 2-(4-methylphenyl)pyrazolo[1,5-a]quinazolin-5(4H)-one [ No CAS ]
  • 2
  • [ 367-57-7 ]
  • [ 78364-55-3 ]
  • [ 7391-28-8 ]
  • [ 1384952-46-8 ]
YieldReaction ConditionsOperation in experiment
88% General procedure: Equimolar amounts of appropriate 2-hydrazinobenzothiazole1a-b, alpha-cyanoacetophenone 2a-c, and PTSA were mixed thoroughly in pestle mortar and heated on water bath for 4-5 min and then equimolar amount of appropriate trifluoromethyl beta-diketones 3a-d was added to it and mixed thoroughly. The reaction mixture was again heated 80-90 ° C for 15 min on water bath. The solid was obtained by addition of aq. ethanol, filtered and crystallized from the mixture of ethanol and chloroform to give pure 4.
  • 3
  • [ 326-06-7 ]
  • [ 78364-55-3 ]
  • [ 7391-28-8 ]
  • [ 1384952-47-9 ]
YieldReaction ConditionsOperation in experiment
84% General procedure: Equimolar amounts of appropriate 2-hydrazinobenzothiazole1a-b, alpha-cyanoacetophenone 2a-c, and PTSA were mixed thoroughly in pestle mortar and heated on water bath for 4-5 min and then equimolar amount of appropriate trifluoromethyl beta-diketones 3a-d was added to it and mixed thoroughly. The reaction mixture was again heated 80-90 ° C for 15 min on water bath. The solid was obtained by addition of aq. ethanol, filtered and crystallized from the mixture of ethanol and chloroform to give pure 4.
  • 4
  • [ 78364-55-3 ]
  • [ 7391-28-8 ]
  • [ 1384952-55-9 ]
YieldReaction ConditionsOperation in experiment
With acetic acid; In ethanol; for 5h;Reflux; General procedure: A mixture of 2-hydrazinobenzothiazole 1a (0.825 g, 5 mmol)and alpha-cyanoacetophenone 2a (0.73 g, 5 mmol) was refluxed in ethanol containing acetic acid (3ml) for 5-6 h. Excess solvent was removed by distillation. The crude product so obtained was recrystallized from ethanol to give 5a (1.09 g, 75percent), Mp 201 ° C (lit.[20], 202 ° C). Other compounds (5b-d) of this type were prepared similarly.
  • 5
  • [ 66-39-7 ]
  • [ 126-81-8 ]
  • [ 7391-28-8 ]
  • 2-amino-7,7-dimethyl-3-(4-methylbenzoyl)-4-(4-(phenylsulfonyl)phenyl)-4,6,7,8-tetrahydroquinolin-5(1H)-one [ No CAS ]
 

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