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Chemical Structure| 74537-63-6 Chemical Structure| 74537-63-6

Structure of 74537-63-6

Chemical Structure| 74537-63-6

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Product Details of [ 74537-63-6 ]

CAS No. :74537-63-6
Formula : C7H5NOS2
M.W : 183.25
SMILES Code : OC1=CC=C2N=C(S)SC2=C1
MDL No. :MFCD23099217
InChI Key :SZNXHOMOAFJDRV-UHFFFAOYSA-N
Pubchem ID :10197960

Safety of [ 74537-63-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P261-P302+P352-P305+P351+P338

Application In Synthesis of [ 74537-63-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 74537-63-6 ]

[ 74537-63-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 74537-63-6 ]
  • [ 74-88-4 ]
  • [ 74537-49-8 ]
YieldReaction ConditionsOperation in experiment
92% With triethylamine; In dichloromethane; at -10 - 0℃; for 3.0h; Step 2. Preparation of 2-Methylsulfanyl-benzothiazol-6-ol To the ice cooled solution of 2-mercapto-benzothiazol-6-ol from step 1 (3.80 g, 20.76 mmol, 1.0 eq) in DCM (40 mL, 0.5M) at 0 C., was added triethylamine (7.29 mL, 51.91 mmol, 2.5 eq) followed by iodomethane (1.93 mL, 31.14 mmol, 1.5 eq). The reaction was stirred from 0 C. to -10 C. for 3 hours. The solvent was removed in vacuo. Water (ca. 200 mL) was added and the aqueous layer was extracted with ethyl acetate (3*150 mL). The organic layer was dried over sodium sulfate, filtered, and evaporated in vacuo to yield 2-methylsulfanyl-benzothiazol-6-ol as light green powder (3.76 g, 92%).
 

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