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Chemical Structure| 845267-57-4 Chemical Structure| 845267-57-4

Structure of 845267-57-4

Chemical Structure| 845267-57-4

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Product Details of [ 845267-57-4 ]

CAS No. :845267-57-4
Formula : C6H6Br2N2O
M.W : 281.93
SMILES Code : BrCC(C1=NC=NC=C1)=O.[H]Br
MDL No. :MFCD11506293

Safety of [ 845267-57-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 845267-57-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 845267-57-4 ]

[ 845267-57-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 845267-57-4 ]
  • [ 50607-30-2 ]
  • 2-(pyrimidin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride [ No CAS ]
YieldReaction ConditionsOperation in experiment
52% Example 13 2-PYRIMIDIN-4-YT-1, 5, 6, 7-TETRAHYDRO-4H-PYRROLO JL 3, 2-CIPVRIDIN-4-O. NE HYD ROCHLORIDE 2-BROMO-1-PYRIMIDIN-4-YLETHANONE hydrobromide (67 mg, 0.239 MMOLS), <strong>[50607-30-2]piperidine-2,4-dione</strong> (50 mg, 0.358 MMOLS) and ammonium acetate (74 mg, 0.957 MMOLS) were dissolved in anhydrous ethanol (1 mL) and stirred at r. t. overnight. The reaction mixture was concentrated to dryness under reduced pressure and the residue was taken up with water (1 mL) and filtered; the solid was washed with cold water and dried. To the obtained brown solid (30 mg) dissolved in MEOH (15 mL), 4N HCI in dioxane (0.5 mL) was added and the mixture was stirred for 30 minutes and then concentrated under reduced pressure to half of the volume. The obtained precipitate was filtered, washed with ethyl acetate and dried to give the title compound as a yellow solid (31 mg, Y=52percent).
 

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