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Chemical Structure| 92203-86-6 Chemical Structure| 92203-86-6

Structure of 92203-86-6

Chemical Structure| 92203-86-6

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Product Details of [ 92203-86-6 ]

CAS No. :92203-86-6
Formula : C8H10N2
M.W : 134.18
SMILES Code : NC1=CC=CC2=C1CNC2
MDL No. :MFCD10000826

Safety of [ 92203-86-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P264-P270-P301+P312-P330-P501

Application In Synthesis of [ 92203-86-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 92203-86-6 ]

[ 92203-86-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 93107-30-3 ]
  • [ 92203-86-6 ]
  • 7-(4-amino-2-isoindolinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
With 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide; Example 17 7-(4-amino-2-isoindolinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid STR146 133 mg of 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 81 mg of 4-aminoisoindoline, 182 mg of DBU, and 1.5 ml of anhydrous DMF were processed in the same manner as in Example 2 to produce 97 mg of the target compound. Melting Point: 240°-244° C. (decomposed) 1 H-NMR (DMSO-d6) delta:8.60 (1H, s, c2 --H), 7.86 (1H, d, J=14HZ, C5 --H), 6.50-7.30 (4H, m, C8 --H, ARM-H), 4.70-5.10 (4H, m, 2 x --CH2 --N--), 3.80 (1H, m, STR147 1.10-1.50 (4H, m, STR148
 

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