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4,4'-dibromo-5,5'-dimethylbiphenyl-2,2'-dicarboxylic acid[ No CAS ]
Yield
Reaction Conditions
Operation in experiment
49%
With sulfuric acid; dibromoisocyanuric acid; at 20.0℃;Cooling with ice;
<strong>[93012-36-3]5,5'-dimethylbiphenyl-2,2'-dicarboxylic acid</strong> 5.0 g and dibromoisocyanuric acid 6.4 g are added to the empty condenser, dissolved in sulfuric acid and stirred.When dibromoisocyanuric acid is dissolved in sulfuric acid, the flask in which the starting material is dissolved is placed in ice water (exothermic), and a sulfuric acid solution in which dibromoisocyanuric acid is dissolved is slowly added to the flask in which the starting material is dissolved.After stirring the flask in ice water for about 1 hour, the flask was moved to room temperature and reacted overnight.During the reaction, distilled water is frozen in the flask.After confirming the reaction through thin film chromatography, the reaction solution was slowly added to the flask in which distilled water was frozen and stirred for several minutes.The resulting yellow solid is filtered under reduced pressure with water.The filtered solid was dissolved in ethyl acetate, and extracted with distilled water and ethyl acetate.The ethyl acetate layer was collected, dried over anhydrous magnesium sulfate, filtered, and the filtrate solvent was removed using a vacuum evaporator to remove 4,4'-dibromo-5,5'-dimethylbiphenyl-2,2'-dicarboxyl. Get Rick Mountain.(3.9 g, yield 49%)
Chemistry
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Material Science
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