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Chemical Structure| 93209-97-3 Chemical Structure| 93209-97-3

Structure of 93209-97-3

Chemical Structure| 93209-97-3

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Product Details of [ 93209-97-3 ]

CAS No. :93209-97-3
Formula : C9H6Cl2N2S
M.W : 245.13
SMILES Code : NC1=NC(C2=CC=C(Cl)C=C2Cl)=CS1
MDL No. :MFCD01114990
InChI Key :APJACVDBTHESJL-UHFFFAOYSA-N
Pubchem ID :704237

Safety of [ 93209-97-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P280-P305+P351+P338-P310

Application In Synthesis of [ 93209-97-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 93209-97-3 ]

[ 93209-97-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 54221-96-4 ]
  • [ 93209-97-3 ]
  • [ 122-52-1 ]
  • diethyl [4-(2,4-dichlorophenyl)thiazol-2-ylamino]-(6-methoxypyridin-2-yl)methanephosphonate [ No CAS ]
YieldReaction ConditionsOperation in experiment
94% With nano-BF3/SiO2; In neat (no solvent); at 20℃; for 0.316667h;Sonication; Green chemistry; General procedure: The mixture of benzaldehyde (3a) (1 mL, 0.010 mol), 2 (2.45 g,0.010 mol) and triethyl phosphite (4) (3.4 mL, 0.020 mol) was placed in a round bottomed flask. To this mixture, 37percent nano-BF3*SiO2 (0.30g) was added and the mixture was irradiated in the ultrasonicator at ambient temperature for about 10 minutes. The progress of the reaction was monitored by TLC (EtOAc/nhexane7:3). After completion of the reaction as checked byTLC, the reaction mixture was cooled to room temperature. CH2Cl2 (15 mL) was added to the reaction content and stirred for 10 min. The catalyst nano-BF3*SiO2 was separated by filtrationas residue, washed with CH2Cl2 (2 × 10 mL) and the residue was dried under vacuum at 100°C to be utilized in further studies. The combined organic layer was washed with water (15 mL), dried over anhydrous Na2SO4 and concentrated under vacuum at 50°C to obtain crude 5a. Pure 5a was obtained by column chromatography (EtOAc/n-hexane 7:3). The same procedure was used for the preparation of the remaining compounds 5b-k.
 

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