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Chemical Structure| 95849-02-8 Chemical Structure| 95849-02-8

Structure of 95849-02-8

Chemical Structure| 95849-02-8

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Product Details of [ 95849-02-8 ]

CAS No. :95849-02-8
Formula : C4H9NO
M.W : 87.12
SMILES Code : OCC1CNC1
MDL No. :MFCD08703352
InChI Key :GNVWVYIAQBJHGV-UHFFFAOYSA-N
Pubchem ID :13400658

Safety of [ 95849-02-8 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H315-H318-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338+P310-P332+P313-P362-P403+P233-P405-P501
Class:8
UN#:1760
Packing Group:

Application In Synthesis of [ 95849-02-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 95849-02-8 ]

[ 95849-02-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 93107-30-3 ]
  • [ 95849-02-8 ]
  • 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[3'-hydroxymethyl-1'-azetidinyl]-4-oxo-3-quinoline-carboxylic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
9.9 mg (59%) With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; EXAMPLE 7 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[3'-hydroxymethyl-1'-azetidinyl]-4-oxo-3-quinoline-carboxylic acid A mixture of 3-hydroxymethyl-1-azetidine 4.4 mg, 0.05 mmole), 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid (10.6 mg, 0.04 mmole) and DBU (0.0113 ml, 12.1 mg, 0.08 mmole) in 5 ml of acetonitrile was refluxed under nitrogen for 3 hours and was then allowed to stand at room temperature under nitrogen overnight. The reaction mixture was then filtered, and the wet cake was washed with acetonitrile and dried in vacuo to give 9.9 mg (59percent) of the title compound, m.p. about 300° C.
 

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[ 95849-02-8 ]

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