Home Cart Sign in  
Chemical Structure| 97337-32-1 Chemical Structure| 97337-32-1

Structure of 97337-32-1

Chemical Structure| 97337-32-1

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 97337-32-1 ]

CAS No. :97337-32-1
Formula : C6H3Cl2N3
M.W : 188.01
SMILES Code : ClC1=CC2=C(N1)N=CN=C2Cl
MDL No. :MFCD11518912
InChI Key :CGTRULURZFVPIX-UHFFFAOYSA-N
Pubchem ID :14431058

Safety of [ 97337-32-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 97337-32-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 97337-32-1 ]

[ 97337-32-1 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 489446-42-6 ]
  • [ 97337-32-1 ]
  • tert-butyl (4-(4,6-dichloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)benzyl)carbamate [ No CAS ]
YieldReaction ConditionsOperation in experiment
13% With 1,10-Phenanthroline; copper diacetate; In N,N-dimethyl-formamide; at 20℃; for 19h; A suspension of 4,6-dichloro-7/-/-pyrrolo[2,3-c ]pyrimidine (940 mg, 5.00 mmol), (4-(((tert- butoxycarbonyl)amino)methyl)phenyl)boronic acid (3.77 g, 15.0 mmol), 1 , 10-phenanthroline (1 .80 g, 10.0 mmol) and copper(l l) acetate (1.82 g, 10.0 mmol) in DMF (100 mL) was stirred at RT for 19 h before being quenched by the addition of saturated NH4CI(aq) (150 mL). The resulting mixture was diluted with water (600 mL) and extracted with EtOAc (3 x 150 mL). The combined organic phases were washed with water (150 mL) and brine (150 (1473) mL), passed through a Biotage phase separator and concentrated in vacuo. The residue was dry loaded onto silica and purified by flash chromatography (Biotage KP-Sil 100 g cartridge, 0-15% EtOAc in cyclohexane) to give a mixture of starting material, product and what is presumed to be homocoupled boronic acid. This material was dry loaded on to silica and purified by flash chromatography (Biotage KP-Sil 100 g cartridge, 0-20% EtOAc in DCM) to give a 1.5: 1 mixture of starting material and product (1 .06 g). This colourless solid was suspended in cyclohexane (-200 mL) and the resulting mixture stirred for 20 min before being filtered. The filtrate was concentrated in vacuo to give the title compound (263 mg, 13%) as a colourless solid. LCMS (Method A): RT = 1.71 min, m/z = 393, 395 [M+H]+. 1 H NMR (500 MHz, DMSO-cfe): delta 8.61 (s, 1 H), 7.53 - 7.44 (m, 5H), 7.08 (s, 1 H), 4.25 (d, J = 6.2 Hz, 2H), 1.42 (s, 9H).
  • 2
  • [ 489446-42-6 ]
  • [ 97337-32-1 ]
  • tert-butyl (4-(6-chloro-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)benzyl)carbamate acetate [ No CAS ]
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 97337-32-1 ]

Chlorides

Chemical Structure| 3680-69-1

A145875 [3680-69-1]

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine

Similarity: 0.98

Chemical Structure| 90994-17-5

A113364 [90994-17-5]

6-Chloro-7H-pyrrolo[2,3-d]pyrimidine

Similarity: 0.95

Chemical Structure| 90213-66-4

A181078 [90213-66-4]

2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine

Similarity: 0.93

Chemical Structure| 552331-44-9

A178078 [552331-44-9]

4,7-Dichloropyrido[2,3-d]pyrimidine

Similarity: 0.93

Chemical Structure| 28732-79-8

A464863 [28732-79-8]

4-Chloropyrido[2,3-d]pyrimidine

Similarity: 0.90

Related Parent Nucleus of
[ 97337-32-1 ]

Other Aromatic Heterocycles

Chemical Structure| 3680-69-1

A145875 [3680-69-1]

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine

Similarity: 0.98

Chemical Structure| 90994-17-5

A113364 [90994-17-5]

6-Chloro-7H-pyrrolo[2,3-d]pyrimidine

Similarity: 0.95

Chemical Structure| 90213-66-4

A181078 [90213-66-4]

2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine

Similarity: 0.93

Chemical Structure| 552331-44-9

A178078 [552331-44-9]

4,7-Dichloropyrido[2,3-d]pyrimidine

Similarity: 0.93

Chemical Structure| 28732-79-8

A464863 [28732-79-8]

4-Chloropyrido[2,3-d]pyrimidine

Similarity: 0.90