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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Fmoc-Glu-OMe is a glutamic acid derivative exhibiting antimicrobial activity and gelation properties in AgNO3 solutions, serving as a plastic wound-healing biomaterial.
Synonyms: Fmoc-Glu-OMe
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Batch number can be found on the product's label following the word 'Batch'.
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Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
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Batch number can be found on the product's label following the word 'Batch'.
CAS No. : | 145038-49-9 |
Formula : | C21H21NO6 |
M.W : | 383.39 |
SMILES Code : | O=C(O)CC[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(OC)=O |
Synonyms : |
Fmoc-Glu-OMe
|
MDL No. : | MFCD21607506 |
GHS Pictogram: |
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Signal Word: | Warning |
Hazard Statements: | H315-H319-H335 |
Precautionary Statements: | P261-P305+P351+P338 |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With triethylsilane; trifluoroacetic acid; In dichloromethane; at 20℃; | General procedure: A dichloromethane solution (10 mL) of Fmoc-AA(OtBu)-OMe (0.3 mmol) was treated with trifluoroacetic acid (1.5 mL) and triethylsilane (0.25 mL) at room temperature. After a check of TLC showed that the starting tert-butyl ether had disappeared (stirring for 2?3 h), the reaction was quenched by addition of distilled water. The separated organic phase was washed with water, dried over sodium sulfate, and filtered. All the solvent was evaporated and the residue was purified with FCC (10 percent Et2O?CH2Cl2) and recrystallization (CH2Cl2?hexane) to give 5d/e (ca. 50?70 percent). |