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Chemical Structure| 145038-49-9 Chemical Structure| 145038-49-9
Chemical Structure| 145038-49-9

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Fmoc-Glu-OMe is a glutamic acid derivative exhibiting antimicrobial activity and gelation properties in AgNO3 solutions, serving as a plastic wound-healing biomaterial.

Synonyms: Fmoc-Glu-OMe

4.5 *For Research Use Only !

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Product Details of Fmoc-Glu-OMe

CAS No. :145038-49-9
Formula : C21H21NO6
M.W : 383.39
SMILES Code : O=C(O)CC[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(OC)=O
Synonyms :
Fmoc-Glu-OMe
MDL No. :MFCD21607506

Safety of Fmoc-Glu-OMe

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of Fmoc-Glu-OMe

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 145038-49-9 ]

[ 145038-49-9 ] Synthesis Path-Downstream   1~35

  • 1
  • [ 145038-49-9 ]
  • [ 543-27-1 ]
  • (S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-5-isobutoxycarbonyloxy-5-oxo-pentanoic acid methyl ester [ No CAS ]
  • 2
  • [ 57933-83-2 ]
  • [ 145038-49-9 ]
  • 2-(9<i>H</i>-fluoren-9-ylmethoxycarbonylamino)-5-isopropenyloxycarbonyloxy-5-oxo-pentanoic acid methyl ester [ No CAS ]
  • 3
  • [ 160002-61-9 ]
  • [ 145038-49-9 ]
YieldReaction ConditionsOperation in experiment
With triethylsilane; trifluoroacetic acid; In dichloromethane; at 20℃; General procedure: A dichloromethane solution (10 mL) of Fmoc-AA(OtBu)-OMe (0.3 mmol) was treated with trifluoroacetic acid (1.5 mL) and triethylsilane (0.25 mL) at room temperature. After a check of TLC showed that the starting tert-butyl ether had disappeared (stirring for 2?3 h), the reaction was quenched by addition of distilled water. The separated organic phase was washed with water, dried over sodium sulfate, and filtered. All the solvent was evaporated and the residue was purified with FCC (10 percent Et2O?CH2Cl2) and recrystallization (CH2Cl2?hexane) to give 5d/e (ca. 50?70 percent).
  • 5
  • [ 443921-86-6 ]
  • [ 145038-49-9 ]
  • [ 443921-82-2 ]
  • 6
  • 2-(9<i>H</i>-fluoren-9-ylmethoxycarbonylamino)-pentanedioic acid 1-(4,5-dimethoxy-2-nitro-benzyl) ester [ No CAS ]
  • [ 18107-18-1 ]
  • [ 145038-49-9 ]
  • 7
  • [ 145038-49-9 ]
  • (S)-2-Amino-4-[4-((S)-2-benzyloxycarbonylamino-2-tert-butoxycarbonyl-ethyl)-benzooxazol-2-yl]-butyric acid methyl ester [ No CAS ]
  • 8
  • [ 145038-49-9 ]
  • methyl (7S,10S,13S)-7-acetylamino-10-carboxymethyl-8,11-dioxo-19-oxa-9,12,17-triazatricyclo[14.2.1.06,18]nonadeca-1(18),2,4,16-tetraene-13-carboxylate [ No CAS ]
  • 9
  • [ 145038-49-9 ]
  • (7S,10S,13S)-7-Acetylamino-10-benzyl-8,11-dioxo-19-oxa-9,12,17-triaza-tricyclo[14.2.1.05,18]nonadeca-1(18),2,4,16-tetraene-13-carboxylic acid [ No CAS ]
  • 10
  • [ 145038-49-9 ]
  • [ 443922-01-8 ]
  • 11
  • [ 145038-49-9 ]
  • (7S,10S,13S)-7-acetylamino-10-benzyl-8,11-dioxo-19-oxa-9,12,17-triazatricyclo[14.2.1.06,18]nonadeca-1(18),2,4,16-tetraene-13-carboxamide [ No CAS ]
  • 12
  • [ 145038-49-9 ]
  • methyl (7S,10S,13S)-7-acetylamino-10-(4-aminobutyl)-8,11-dioxo-19-oxa-9,12,17-triazatricyclo[14.2.1.06,18]nonadeca-1(18),2,4,16-tetraene-13-carboxylate [ No CAS ]
  • 13
  • [ 145038-49-9 ]
  • [ 443921-98-0 ]
  • 14
  • [ 145038-49-9 ]
  • [ 443921-99-1 ]
  • 15
  • [ 145038-49-9 ]
  • [ 443922-04-1 ]
  • 16
  • [ 145038-49-9 ]
  • [ 443921-80-0 ]
  • 17
  • [ 145038-49-9 ]
  • [ 443921-89-9 ]
  • 18
  • [ 145038-49-9 ]
  • [ 443922-00-7 ]
  • 19
  • [ 145038-49-9 ]
  • [ 443921-90-2 ]
  • 20
  • [ 145038-49-9 ]
  • [ 443921-91-3 ]
  • 21
  • [ 145038-49-9 ]
  • (S)-2-((S)-2-Amino-3-phenyl-propionylamino)-4-[4-((S)-2-benzyloxycarbonylamino-2-carboxy-ethyl)-benzooxazol-2-yl]-butyric acid methyl ester; compound with trifluoro-acetic acid [ No CAS ]
  • 22
  • [ 145038-49-9 ]
  • 2-(9<i>H</i>-fluoren-9-ylmethoxycarbonylamino)-4-{2'-[3-(9<i>H</i>-fluoren-9-ylmethoxycarbonylamino)-3-methoxycarbonyl-propyl]-[4,4']bibenzooxazolyl-2-yl}-butyric acid methyl ester [ No CAS ]
  • 23
  • [ 145038-49-9 ]
  • (S)-3-Amino-N-{(S)-3-[4-((S)-2-benzyloxycarbonylamino-2-carboxy-ethyl)-benzooxazol-2-yl]-1-methoxycarbonyl-propyl}-succinamic acid benzyl ester; compound with trifluoro-acetic acid [ No CAS ]
  • 24
  • [ 145038-49-9 ]
  • (S)-2-[(S)-2-Amino-6-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-hexanoylamino]-4-[4-((S)-2-benzyloxycarbonylamino-2-carboxy-ethyl)-benzooxazol-2-yl]-butyric acid methyl ester; compound with trifluoro-acetic acid [ No CAS ]
  • 25
  • [ 71989-18-9 ]
  • Fmoc-Leu-OH [ No CAS ]
  • [ 145038-49-9 ]
  • 27
  • [ 145038-49-9 ]
  • (S)-2-Amino-6-bromo-5-oxo-hexanoic acid [ No CAS ]
  • 28
  • [ 145038-49-9 ]
  • (S)-2-Amino-6-chloro-5-oxo-hexanoic acid [ No CAS ]
  • 29
  • [ 145038-49-9 ]
  • (S)-2-Amino-6-diazo-5-oxo-heptanoic acid [ No CAS ]
  • 30
  • [ 145038-49-9 ]
  • 6-diazo-2-(9<i>H</i>-fluoren-9-ylmethoxycarbonylamino)-5-oxo-hexanoic acid methyl ester [ No CAS ]
  • 31
  • [ 145038-49-9 ]
  • 6-diazo-2-(9<i>H</i>-fluoren-9-ylmethoxycarbonylamino)-5-oxo-heptanoic acid methyl ester [ No CAS ]
  • 32
  • [ 145038-49-9 ]
  • [ 148383-12-4 ]
  • 33
  • [ 145038-49-9 ]
  • [ 182005-24-9 ]
  • 34
  • [ 145038-49-9 ]
  • [ 182005-30-7 ]
 

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