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Chemical Structure| 10563-29-8 Chemical Structure| 10563-29-8

Structure of 10563-29-8

Chemical Structure| 10563-29-8

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Product Citations

Product Citations

Li, Bowen ; Manan, Rajith Singh ; Liang, Shun-Qing ; Gordon, Akiva ; Jiang, Allen ; Varley, Andrew , et al.

Abstract: The expanding applications of nonviral genomic medicines in the lung remain restricted by delivery challenges. Here, leveraging a high-throughput platform, we synthesize and screen a combinatorial library of biodegradable ionizable lipids to build inhalable delivery vehicles for mRNA and CRISPR-Cas9 gene editors. Lead lipid nanoparticles are amenable for repeated intratracheal dosing and could achieve efficient gene editing in lung epithelium, providing avenues for gene therapy of congenital lung diseases.

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Product Details of [ 10563-29-8 ]

CAS No. :10563-29-8
Formula : C8H21N3
M.W : 159.27
SMILES Code : CN(C)CCCNCCCN
MDL No. :MFCD00082192

Safety of [ 10563-29-8 ]

Application In Synthesis of [ 10563-29-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 10563-29-8 ]

[ 10563-29-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 10563-29-8 ]
  • [ 120085-99-6 ]
  • 2,9-bis{4-[(3-(3-dimethylaminopropylamino)propyl)iminomethyl]phenyl}-1,10-phenanthroline [ No CAS ]
 

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