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Chemical Structure| 14916-80-4 Chemical Structure| 14916-80-4

Structure of 14916-80-4

Chemical Structure| 14916-80-4

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Product Citations

Product Citations

Li, Bowen ; Manan, Rajith Singh ; Liang, Shun-Qing ; Gordon, Akiva ; Jiang, Allen ; Varley, Andrew , et al.

Abstract: The expanding applications of nonviral genomic medicines in the lung remain restricted by delivery challenges. Here, leveraging a high-throughput platform, we synthesize and screen a combinatorial library of biodegradable ionizable lipids to build inhalable delivery vehicles for mRNA and CRISPR-Cas9 gene editors. Lead lipid nanoparticles are amenable for repeated intratracheal dosing and could achieve efficient gene editing in lung epithelium, providing avenues for gene therapy of congenital lung diseases.

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Product Details of [ 14916-80-4 ]

CAS No. :14916-80-4
Formula : C8H14O
M.W : 126.20
SMILES Code : CCCCC#CCCO
MDL No. :MFCD00039552
InChI Key :LRZGRGVRZSDRTK-UHFFFAOYSA-N
Pubchem ID :84694

Safety of [ 14916-80-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338
 

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[ 14916-80-4 ]

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