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Chemical Structure| 110-94-1 Chemical Structure| 110-94-1
Chemical Structure| 110-94-1

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Glutaric Acid is a C5 dicarboxylic acid and an intermediate in the catabolic pathways of tryptophan and lysine. It affects the contractility and migration of pericytes and serves as a biomarker for type I glutaric aciduria.

Synonyms: GA

4.5 *For Research Use Only !

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Product Citations

Product Citations

Keeler, Courtney Marie ;

Abstract: Polyhydroxyalkanoates are a class of biodegradable polyester, typically produced by fermentation, that could be a viable replacement to some petroleum-based plastics. This polymer is attractive to research because it is biodegradable, biocompatible, and does not form any microplastics which are harmful to both human health and the environment. PHAs show much promise, but have several factors to overcome including cost, availability, slow nucleation, poor mechanical properties, and aging which decreases PHAs flexibility over time. In this study, the latter two issues are focused on, as several biobased aliphatic polyesters are evaluated as additives to polyhydroxyalkanoates (PHAs) with the goal of increasing flexibility and preventing secondary crystallization. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) with 6% and 8% hexanoate are the two PHAs utilized in this project. Blending and reactive extrusion of these PHAs and additives include polylactide, peroxide radical initiator, and novel aliphatic copolyesters synthesized by polycondensation is explored.

Keywords: Biodegradable ; polyhydroxyalkanoates ; polyesters ; extrusion ; polycondensation ; tensile testing

Purchased from AmBeed: ; ; ; ; ; ; ; 1071-76-7

Alternative Products

Product Details of Glutaric Acid

CAS No. :110-94-1
Formula : C5H8O4
M.W : 132.11
SMILES Code : O=C(O)CCCC(O)=O
Synonyms :
GA
MDL No. :MFCD00004410
InChI Key :JFCQEDHGNNZCLN-UHFFFAOYSA-N
Pubchem ID :743

Safety of Glutaric Acid

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P260-P264-P280-P305+P351+P338-P405-P501
Class:8
UN#:3261
Packing Group:

Application In Synthesis of Glutaric Acid

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 110-94-1 ]

[ 110-94-1 ] Synthesis Path-Downstream   1~28

  • 1
  • [ 110-94-1 ]
  • [ 623-81-4 ]
  • [ 1070-62-8 ]
  • 2
  • [ 110-94-1 ]
  • [ 3452-97-9 ]
  • glutaric acid bis-(3,5,5-trimethyl-hexyl ester) [ No CAS ]
  • 3
  • [ 110-94-1 ]
  • [ 818-38-2 ]
  • [ 1070-62-8 ]
  • 4
  • [ 63128-51-8 ]
  • [ 110-94-1 ]
  • [ 115-11-7 ]
  • 5
  • [ 110-94-1 ]
  • [ 74-89-5 ]
  • [ 25077-25-2 ]
  • [ 56269-42-2 ]
  • 7
  • [ 110-94-1 ]
  • [ 1454-85-9 ]
  • [ 26720-17-2 ]
  • 8
  • [ 1070-62-8 ]
  • [ 110-94-1 ]
  • 9
  • [ 117903-19-2 ]
  • [ 110-94-1 ]
  • [ 64-17-5 ]
  • [ 1070-62-8 ]
  • [ 53594-71-1 ]
  • [ 67-63-0 ]
  • 10
  • [ 110-94-1 ]
  • [ 74-89-5 ]
  • [ 25077-25-2 ]
  • 11
  • [ 1004-38-2 ]
  • [ 110-94-1 ]
  • pyrimidine-2,4,6-triamine; compound with pentanedioic acid [ No CAS ]
  • 12
  • [ 818-38-2 ]
  • Al2O3 [ No CAS ]
  • [ 110-94-1 ]
  • [ 74-85-1 ]
  • [ 1070-62-8 ]
  • 14
  • [ 110-94-1 ]
  • [ 1070-62-8 ]
  • 15
  • [ 110-94-1 ]
  • cobalt(II) acetate [ No CAS ]
  • [ 151433-25-9 ]
  • [(1-RR)-(Glutaric acid)] [ No CAS ]
YieldReaction ConditionsOperation in experiment
100% 1.8 g of (R, R) -N,N'-bis (3, 5-di-t-butylsalicylidene) -1,2- cyclohexanediamine and 1.1 g of cobalt (II) acetate-4H2O were mixed in 35 ml of ethanol and stirred under reflux for 5 hours. They were filtered at room temperature and cleaned by small amount of ethanol. The obtained solid was uniformly divided into four parts and mixed with 6 ml of acetone and 10 ml of dichloromethane respectively. Also, 1.0 equivalent weight of succinic acid, glutaric acid, adipic acid, and pimeric acid were added respectively and stirred for 3 hours with injection of air at room temperature. After the solvent was eliminated under reduced pressure, the title compounds were obtained quantitatively.
  • 16
  • [ 110-94-1 ]
  • [ 173334-57-1 ]
  • aliskiren glutaric acid salt [ No CAS ]
YieldReaction ConditionsOperation in experiment
In ethanol; dichloromethane; at 20℃; for 24h; Example 23: Preparation of aliskiren glutaric acid salt <strong>[173334-57-1]Aliskiren</strong> (1.6 g, 2.9 mmol) was dissolved in dichloromethane (10 mL), and glutaric acid (0.191 g, 1.45 mmol) in ethanol (1 mL) was added while stirring. The solution was stirred at room temperature for 24 h. Then, the solvent was evaporated in vacuum and the product was dried under vacuum at 30C over night. Mp = 71.5-75.8C XRPD: amorphous
  • 17
  • [ 75-91-2 ]
  • [ 504-02-9 ]
  • [ 110-94-1 ]
  • [ 3885-29-8 ]
  • [ 868-57-5 ]
  • [ 63128-51-8 ]
  • [ 75-07-0 ]
  • [ 141-78-6 ]
  • [ 75-65-0 ]
  • 18
  • [ 110-94-1 ]
  • zinc(II) nitrate hexahydrate [ No CAS ]
  • [ 2645-22-9 ]
  • [ 7732-18-5 ]
  • [zinc(II)(glutarate)(4,4'-dipyridyl disulfide)]*5H2O [ No CAS ]
  • 19
  • [ 110-94-1 ]
  • [ 4054-67-5 ]
  • [ 20667-12-3 ]
  • [(silver)4(3,3′,5,5′-tetramethyl-4,4′-bipyrazole)5(glutarate)2] [ No CAS ]
  • 20
  • [ 82410-79-5 ]
  • [ 110-94-1 ]
  • aqueous cadmium chloride [ No CAS ]
  • [Cd2(1,4-bis(2-methylimidazol-1-ylmethyl)benzene)(glutarate)2]n [ No CAS ]
YieldReaction ConditionsOperation in experiment
46% With sodium hydroxide; In ethanol; at 110.0℃; for 72h;pH 7.0;Autoclave; General procedure: A solution of H2fum (0.2 mmol) or H2glu (0.2 mmol) in 5 mL H2O was adjusted to pH7 with dilute NaOH. Then bix (0.2 mmol) in 5 mL EtOH and CdCl2·2.5H2O (0.2 mmol) in 5 mL H2O were added. The mixture was added to a 30 mL Teflon-lined stainless autoclave and this was sealed and heated to 110C for 3days and then cooled to room temperature to give the colorless crystals 1 in 38% yield based on Cd(II) (0.036 g) or 2 in 46% yield based on Cd(II) (0.035 g). Anal. calcd. for C36H39Cd2Cl2N8O4.50 (1) C, 45.45; H, 4.13; N, 11.78. Found: C, 45.39%; H, 4.08%; N, 11.74%. Anal. calcd. for C26H30Cd2N4O8 (2) C, 41.56; H, 4.02; N, 7.46. Found: C, 41.53%; H, 3.97%; N,7.44 %.
  • 21
  • [ 82410-79-5 ]
  • [ 110-94-1 ]
  • cobalt(II) nitrate hexahydrate [ No CAS ]
  • [Co2(1,4-bis(2-methylimidazol-1-methyl)benzene)(glutarate)2]n [ No CAS ]
YieldReaction ConditionsOperation in experiment
53% With sodium hydroxide; In ethanol; water; at 90.0℃; for 72h;pH 7.0;Autoclave; General procedure: A solution of H2ndc (0.2mmol) in 8mL H2O was adjusted to pH 7 with dilute NaOH. Then bix (0.2mmol) in 7mL EtOH and Co(NO3)2·6H2O (0.2mmol) in 7mL H2O were added. The mixture was added to a 30mL Teflon-lined stainless autoclave and it was sealed and heated to 90C for 3days, then cooled to room temperature to give red crystals of 1 in 56% yield (0.060g).
  • 23
  • [ 110-94-1 ]
  • [ 39769-09-0 ]
  • C18H15F2NO3 [ No CAS ]
  • C18H15F2NO3 [ No CAS ]
  • 24
  • [ 82410-79-5 ]
  • [ 110-94-1 ]
  • copper(II) nitrate dihydrate [ No CAS ]
  • [Cu(1,4-bis(2-methyl-imidazol-1-methyl)benzene)0.5(glu)]n [ No CAS ]
YieldReaction ConditionsOperation in experiment
47% With sodium hydroxide; In ethanol; water; at 90.0℃; for 72h;Autoclave; High pressure; General procedure: The solution of bix (0.2 mmol) in 5 mL EtOH and Cd(NO3)2.6H2O(0.2 mmol) in 5 mL H2O were added to H2mbda (0.20 mmol) andNaOH (0.18 mmol) in 5 mL H2O. The mixture was added to a30 mL Teflon-lined stainless autoclave and this was sealed and heated to 90 C for 3 days and then cooled to room temperature to give the colorless crystals 3 (Yield: 0.064 g, 56% based on H2-mbda ligand).
  • 25
  • [ 26787-78-0 ]
  • [ 3973-08-8 ]
  • [ 740742-98-7 ]
  • [ 64-18-6 ]
  • [ 79-14-1 ]
  • [ 110-94-1 ]
  • [ 124-04-9 ]
  • [ 80-69-3 ]
  • [ 473-81-4 ]
  • [ 471-47-6 ]
  • [ 110-15-6 ]
  • [ 1378848-02-2 ]
  • [ 15573-67-8 ]
  • C9H10N2O4 [ No CAS ]
  • C9H12N2O5S [ No CAS ]
  • C8H10N2O6S [ No CAS ]
  • C9H14N2O7S [ No CAS ]
  • C9H12N2O6S [ No CAS ]
  • C8H10N2O4S [ No CAS ]
  • C10H12N2O7S [ No CAS ]
  • C15H21N3O4S [ No CAS ]
  • C15H18N2O4S [ No CAS ]
  • C14H21N3O3S [ No CAS ]
  • C8H12N2O4S [ No CAS ]
  • C8H10N2O5S [ No CAS ]
  • C6H10O7S [ No CAS ]
  • C6H7NO4S [ No CAS ]
  • C6H11NO3S [ No CAS ]
  • C6H9NO3S [ No CAS ]
  • [ 144-62-7 ]
  • [ 64-19-7 ]
  • [ 802294-64-0 ]
  • [ 127-17-3 ]
  • [ 87-69-4 ]
  • [ 551-16-6 ]
  • [ 65-85-0 ]
  • [ 298-12-4 ]
  • 2-hydroxy-3-(4-hydroxyphenyl)pyrazine [ No CAS ]
  • [ 6915-18-0 ]
  • [ 107-92-6 ]
  • [ 57457-65-5 ]
  • [ 99-96-7 ]
  • 26
  • [ 82410-79-5 ]
  • [ 110-94-1 ]
  • nickel(II) nitrate hexahydrate [ No CAS ]
  • [ 7732-18-5 ]
  • 2Ni(2+)*2C5H6O4(2-)*2C16H18N4*3H2O [ No CAS ]
YieldReaction ConditionsOperation in experiment
46% A mixture of glutaric acid (0.061 g,0.5 mmol), Ni(NO3)26H2O (0.145 g, 0.5 mmol), 1,4-mbix(0.134 g, 0.5 mmol) and water (10 ml) was stirred for 30 min.The pH of the mixture was adjusted to 6.0 with 1 mol l1NaOH solution and the resulting mixture was transferred toand sealed in a 25 ml Teflon-lined stainless steel container andheated at 160 C for 3 d. After slow cooling to room temperature,green block-shaped crystals of (I) were collected in 46%yield (based on the NiII salt). Elemental analysis (%) calculatedfor C42H54N8Ni2O11: C 52.31, H 5.64, N 11.62; found: C 52.18, H 5.71, N 11.48. IR (KBr, cm1): 3411 (s), 3136 (w), 2940(w), 1636 (w), 1616 (s), 1557 (w), 1517 (w), 1454 (w), 1398 (s),1271 (w), 1104 (w), 910 (w), 805 (w), 740 (m), 611 (w).
  • 27
  • [ 82410-79-5 ]
  • [ 110-94-1 ]
  • zinc(II) nitrate hexahydrate [ No CAS ]
  • [ 7732-18-5 ]
  • C5H6O4(2-)*C16H18N4*4H2O*Zn(2+) [ No CAS ]
YieldReaction ConditionsOperation in experiment
62% General procedure: A mixture of glutaric acid (0.061 g,0.5 mmol), Ni(NO3)26H2O (0.145 g, 0.5 mmol), 1,4-mbix(0.134 g, 0.5 mmol) and water (10 ml) was stirred for 30 min.The pH of the mixture was adjusted to 6.0 with 1 mol l1NaOH solution and the resulting mixture was transferred toand sealed in a 25 ml Teflon-lined stainless steel container andheated at 160 C for 3 d. After slow cooling to room temperature,green block-shaped crystals of (I) were collected in 46%yield (based on the NiII salt).
  • 28
  • [ 110-94-1 ]
  • [ 870-78-0 ]
  • [ 7209-00-9 ]
 

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