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Chemical Structure| 1255760-30-5 Chemical Structure| 1255760-30-5

Structure of 1255760-30-5

Chemical Structure| 1255760-30-5

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Product Details of [ 1255760-30-5 ]

CAS No. :1255760-30-5
Formula : C12H15BCl2O2
M.W : 272.96
SMILES Code : CC1(C)C(C)(C)OB(C2=CC=CC(Cl)=C2Cl)O1
MDL No. :MFCD18729912
InChI Key :XJOWNMGMNMPVRL-UHFFFAOYSA-N
Pubchem ID :66787849

Safety of [ 1255760-30-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H312-H332
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501

Application In Synthesis of [ 1255760-30-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1255760-30-5 ]

[ 1255760-30-5 ] Synthesis Path-Downstream   1~9

  • 1
  • [ 2401-21-0 ]
  • [ 73183-34-3 ]
  • [ 1255760-30-5 ]
YieldReaction ConditionsOperation in experiment
74.5% With potassium acetate;(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In dimethyl sulfoxide; at 20 - 85℃; for 4.66667h; Synthesis of 2-(2,3-dichlorophenyl)-4,4,5,5-tetramethyl-1,3-2-dioxaborolane(Compound 16)[0167] A mixture of 1,2-dichloro-3-iodobenzene (7.9229 g, 28.50 mmol), bis(pinacolato)diboron (12.8674 g, 50.20 mmol), potassium acetate (8.0214 g, 82 mmol) and 1,1'-[bis(bisphenyl phosphino)ferrocene]dichloropalladium (II) (1.010 g, 1.38 mmol) in anhydrous DMSO (88 mL) was stirred at room temperature for ten minutes at 85 °C (oil bath temperature) for 4.5 hours. The mixture was cooled to room temperature and poured into ice. The mixture was extracted with EtOAc (3 x 150 mL). The combined organic solution was washed with sat. NaCl (3x100 mL), dried over Na2SO4, and concentrated. The resulting residue was purified with flash column chromatography on silica gel to afford 5.7869 g of the desired product as white solid in 74.5percent yield. 1H-NMR (CDCl3): delta 7.557 (dd, J= 7.0-8.0 Hz and 1.5 Hz, 1 H), 7.050 (dd, J= 7.5-8.0 Hz and 1.5 Hz, 1 H), 7.172 (d, J= 7.5-8.0 Hz, 1 H), 1.368 (s, 9 H).
  • 3
  • [ 1255760-30-5 ]
  • C48H64Br2 [ No CAS ]
  • C60H70Cl4 [ No CAS ]
  • 4
  • [ 1255760-30-5 ]
  • 2,6-dibromo-5'-phenyl-4-tetradecyl-1,1':3',1''-terphenyl [ No CAS ]
  • C50H50Cl4 [ No CAS ]
  • 5
  • [ 1255760-30-5 ]
  • 2,6-dibromo-5'-phenyl-4-tetradecyl-1,1':3',1''-terphenyl [ No CAS ]
  • C50H46 [ No CAS ]
  • 6
  • [ 1255760-30-5 ]
  • C29H17BrO [ No CAS ]
  • C35H20Cl2O [ No CAS ]
YieldReaction ConditionsOperation in experiment
91.1% With tetrakis(triphenylphosphine) palladium(0); sodium hydroxide; In tetrahydrofuran; water; for 6.0h; Sub 2-16a (48 g, 0.10 mol) in <strong>[1255760-30-5]2-(2,3-dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane</strong>(28.4 g, 0.10 mol), Pd(PPh3)4 (3.6 g, 0.003 mol),NaOH (12.5 g, 0.31 mol), THF (210 mL), and water (70 mL) were added, followed by reaction for 6 hours. When the reaction is complete,Using the separation method of Sub 1-1b, the product50 g (91.1%) of Sub 2-16b was obtained.
  • 7
  • [ 1255760-30-5 ]
  • C35H19ClO [ No CAS ]
  • 8
  • [ 1255760-30-5 ]
  • C41H24ClNO [ No CAS ]
  • 9
  • [ 1255760-30-5 ]
  • C41H23NO [ No CAS ]
 

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Technical Information

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Related Functional Groups of
[ 1255760-30-5 ]

Organoborons

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Aryls

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Chlorides

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