Home Cart 0 Sign in  

[ CAS No. 175278-09-8 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

type HazMat fee
Excepted Quantity Free
Inaccessible (Haz class 6.1), Domestic USD 41.00
Inaccessible (Haz class 6.1), International USD 64.00
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 83.00
Accessible (Haz class 3, 4, 5 or 8), International USD 133.00
Chemical Structure| 175278-09-8
Chemical Structure| 175278-09-8
Structure of 175278-09-8 * Storage: {[proInfo.prStorage]}

Quality Control of [ 175278-09-8 ]

Related Doc. of [ 175278-09-8 ]

SDS
Alternatived Products of [ 175278-09-8 ]
Alternatived Products of [ 175278-09-8 ]

Product Details of [ 175278-09-8 ]

CAS No. :175278-09-8 MDL No. :MFCD00179338
Formula : C7H5BrF3NO Boiling Point : 209.2°C at 760 mmHg
Linear Structure Formula :- InChI Key :-
M.W :256.02 g/mol Pubchem ID :737382
Synonyms :

Safety of [ 175278-09-8 ]

Signal Word:Danger Class:6.1
Precautionary Statements:P280-P301+P310 UN#:2810
Hazard Statements:H301-H317-H412 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 175278-09-8 ]

  • Upstream synthesis route of [ 175278-09-8 ]
  • Downstream synthetic route of [ 175278-09-8 ]

[ 175278-09-8 ] Synthesis Path-Upstream   1~4

  • 1
  • [ 175278-09-8 ]
  • [ 2252-44-0 ]
Reference: [1] Patent: WO2007/107820, 2007, A2, . Location in patent: Page/Page column 7
  • 2
  • [ 1535-75-7 ]
  • [ 175278-09-8 ]
Reference: [1] Patent: WO2007/107820, 2007, A2, . Location in patent: Page/Page column 7
  • 3
  • [ 67-56-1 ]
  • [ 175278-09-8 ]
  • [ 201230-82-2 ]
  • [ 457097-93-7 ]
YieldReaction ConditionsOperation in experiment
54% at 100℃; for 36 h; To a solution of 4-bromo-2-(trifluoromethoxy)aniline (10 g, 50.21 mmol) in methanol (150 mL) in a pressure tank reactor was added TEA (11.84 g, 117.01 mmol), Pd(dppf)Ci2 CH2Q2 (2.4 g, 2.94 mmol). Then the reactor was charged with CO (g) (20 atm). The resulting reaction was stirred for 1.5 days at 100°C. Then it was diluted with water (200 mL), extracted with ethyl acetate (3 x 100 mL) and the organic layers combined and dried in an oven under reduced pressure. The resulting mixture was concentrated in vacuo. The residue was purified by silica gel column chromatography with ethyl acetate/petroleum ether (1 :50) to afford methyl 4- amino-3-(trifluoromethoxy)benzoate as yellow solid (5 g, 54percent).
Reference: [1] Patent: WO2014/66795, 2014, A1, . Location in patent: Paragraph 0175
  • 4
  • [ 175278-09-8 ]
  • [ 886500-50-1 ]
Reference: [1] Patent: WO2014/66795, 2014, A1,
Historical Records

Related Functional Groups of
[ 175278-09-8 ]

Trifluoromethyls

Chemical Structure| 886762-08-9

[ 886762-08-9 ]

5-Bromo-2-(trifluoromethoxy)aniline

Similarity: 0.98

Chemical Structure| 175278-17-8

[ 175278-17-8 ]

2-Bromo-4-(trifluoromethoxy)aniline

Similarity: 0.90

Chemical Structure| 887267-47-2

[ 887267-47-2 ]

2-Bromo-5-(trifluoromethoxy)aniline

Similarity: 0.90

Chemical Structure| 88149-49-9

[ 88149-49-9 ]

2,6-Dibromo-4-(trifluoromethoxy)aniline

Similarity: 0.87

Chemical Structure| 1535-75-7

[ 1535-75-7 ]

2-(Trifluoromethoxy)aniline

Similarity: 0.84

Fluorinated Building Blocks

Chemical Structure| 886762-08-9

[ 886762-08-9 ]

5-Bromo-2-(trifluoromethoxy)aniline

Similarity: 0.98

Chemical Structure| 175278-17-8

[ 175278-17-8 ]

2-Bromo-4-(trifluoromethoxy)aniline

Similarity: 0.90

Chemical Structure| 887267-47-2

[ 887267-47-2 ]

2-Bromo-5-(trifluoromethoxy)aniline

Similarity: 0.90

Chemical Structure| 88149-49-9

[ 88149-49-9 ]

2,6-Dibromo-4-(trifluoromethoxy)aniline

Similarity: 0.87

Chemical Structure| 1535-75-7

[ 1535-75-7 ]

2-(Trifluoromethoxy)aniline

Similarity: 0.84

Bromides

Chemical Structure| 886762-08-9

[ 886762-08-9 ]

5-Bromo-2-(trifluoromethoxy)aniline

Similarity: 0.98

Chemical Structure| 175278-17-8

[ 175278-17-8 ]

2-Bromo-4-(trifluoromethoxy)aniline

Similarity: 0.90

Chemical Structure| 887267-47-2

[ 887267-47-2 ]

2-Bromo-5-(trifluoromethoxy)aniline

Similarity: 0.90

Chemical Structure| 88149-49-9

[ 88149-49-9 ]

2,6-Dibromo-4-(trifluoromethoxy)aniline

Similarity: 0.87

Chemical Structure| 59557-91-4

[ 59557-91-4 ]

4-Bromo-2-methoxyaniline

Similarity: 0.84

Amines

Chemical Structure| 886762-08-9

[ 886762-08-9 ]

5-Bromo-2-(trifluoromethoxy)aniline

Similarity: 0.98

Chemical Structure| 175278-17-8

[ 175278-17-8 ]

2-Bromo-4-(trifluoromethoxy)aniline

Similarity: 0.90

Chemical Structure| 887267-47-2

[ 887267-47-2 ]

2-Bromo-5-(trifluoromethoxy)aniline

Similarity: 0.90

Chemical Structure| 88149-49-9

[ 88149-49-9 ]

2,6-Dibromo-4-(trifluoromethoxy)aniline

Similarity: 0.87

Chemical Structure| 1535-75-7

[ 1535-75-7 ]

2-(Trifluoromethoxy)aniline

Similarity: 0.84

Aryls

Chemical Structure| 886762-08-9

[ 886762-08-9 ]

5-Bromo-2-(trifluoromethoxy)aniline

Similarity: 0.98

Chemical Structure| 175278-17-8

[ 175278-17-8 ]

2-Bromo-4-(trifluoromethoxy)aniline

Similarity: 0.90

Chemical Structure| 887267-47-2

[ 887267-47-2 ]

2-Bromo-5-(trifluoromethoxy)aniline

Similarity: 0.90

Chemical Structure| 88149-49-9

[ 88149-49-9 ]

2,6-Dibromo-4-(trifluoromethoxy)aniline

Similarity: 0.87

Chemical Structure| 1535-75-7

[ 1535-75-7 ]

2-(Trifluoromethoxy)aniline

Similarity: 0.84

Ethers

Chemical Structure| 886762-08-9

[ 886762-08-9 ]

5-Bromo-2-(trifluoromethoxy)aniline

Similarity: 0.98

Chemical Structure| 175278-17-8

[ 175278-17-8 ]

2-Bromo-4-(trifluoromethoxy)aniline

Similarity: 0.90

Chemical Structure| 887267-47-2

[ 887267-47-2 ]

2-Bromo-5-(trifluoromethoxy)aniline

Similarity: 0.90

Chemical Structure| 88149-49-9

[ 88149-49-9 ]

2,6-Dibromo-4-(trifluoromethoxy)aniline

Similarity: 0.87

Chemical Structure| 1535-75-7

[ 1535-75-7 ]

2-(Trifluoromethoxy)aniline

Similarity: 0.84