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Chemical Structure| 5330-48-3 Chemical Structure| 5330-48-3

Structure of 5330-48-3

Chemical Structure| 5330-48-3

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Kurohara, Takashi ; Tatebe, Chiye ; Fujiwara, Yumiko ; Takada, Shohei ; Ishizuki, Kyoko ; Fujihara, Koji , et al.

Abstract: 3-[N-Ethyl-N-(4-sulfophenyl)amino]methylbenzenesulfonic acid (m,p-ESBSA) is a common impurity in (Food Blue No.1: B1) and (Food Green No.3: G3). For the quality control of B1 and G3, quantitative analysis of m,p-ESBSA is required. However, no analytical-grade m,p-ESBSA suitable as a quantitative standard is readily available. In this study, we established an efficient synthesis that provides m,p-ESBSA with a quality that can be used for quantitative analysis. The synthetic route to m,p-ESBSA involves inexpensive starting materials, and the product was structurally characterized by detailed NMR analysis. In addition, the suitability of the synthesized samples for quantitative analysis was confirmed by 1H-qNMR analysis and quantitation of food dye products. The results showed that the purity of the synthesized m,p-ESBSA was adequate for use as an analytical standard in quantitative analyses.

Keywords: ESBSA ; organic synthesis ; ; ; qNMR

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Product Details of [ 5330-48-3 ]

CAS No. :5330-48-3
Formula : C7H5NaO4S
M.W : 208.17
SMILES Code : O=S(C1=CC=CC(C=O)=C1)([O-])=O.[Na+]
MDL No. :MFCD09863878
InChI Key :AFIUOLGCFDPAKN-UHFFFAOYSA-M
Pubchem ID :23690338

Safety of [ 5330-48-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
 

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