58755-91-2|2-(4-Chlorophenyl)succinic acid| Ambeed

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Quality Control of [ 58755-91-2 ] Purity: 95% SDS Specification

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NMR

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Product Details of [ 58755-91-2 ]

CAS No. :	58755-91-2
Formula :	C₁₀H₉ClO₄
M.W :	228.63
SMILES Code :	O=C(O)C(C1=CC=C(Cl)C=C1)CC(O)=O
MDL No. :	MFCD00598653
InChI Key :	AGFXJIDIVHRKCA-UHFFFAOYSA-N
Pubchem ID :	580487

Safety of [ 58755-91-2 ]

GHS Pictogram:
Signal Word:	Warning
Hazard Statements:	H302-H315-H319-H335
Precautionary Statements:	P261-P305+P351+P338

Application In Synthesis of [ 58755-91-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 58755-91-2 ]

[ 58755-91-2 ] Synthesis Path-Downstream 1~25

1
[ 58755-91-2 ]
[ 1628-19-9 ]

Yield	Reaction Conditions	Operation in experiment
	With ammonium hydroxide; at 180℃;Heating;	General procedure: A total of 0.05 mol of the 2-phenyl- (1), 2-(2-chlorophenyl)- (2), 2-(3-chlorophenyl)- (3) or 2-(4-chlorophenyl)- (4) succinic acids were suspended in 20 ml of water and 0.05 mol of the 25% ammonia was gradually added. The mixture was heated in a term-regulated sand bath (ST 72 Roth, Karlsruhe, Germany) with simultaneous distillation of water. After complete removal of water, the temperature of the reaction mixture raised up to 180 C and was maintained for 1 h. The crude products were recrystallized from methanol. The physicochemical and spectral data of intermediates 5-8 have been described in a separate paper.18

References: [1]Journal of the American Chemical Society,1953,vol. 75,p. 6256.
[2]Archiv der Pharmazie,2010,vol. 343,p. 333 - 341.
[3]Bioorganic and Medicinal Chemistry,2013,vol. 21,p. 6821 - 6830.

2
[ 151-50-8 ]
[ 104-88-1 ]
[ 105-56-6 ]
[ 58755-91-2 ]

References: [1]Proceedings - Indian Academy of Sciences, Section A,1941,p. 139,143.

3
[ 58755-91-2 ]
[ 75-04-7 ]
[ 91395-94-7 ]

References: [1]Journal of the American Chemical Society,1953,vol. 75,p. 6256.

4
[ 58755-91-2 ]
[ 75-31-0 ]
3-(4-chloro-phenyl)-1-isopropyl-pyrrolidine-2,5-dione [ No CAS ]

References: [1]Journal of the American Chemical Society,1953,vol. 75,p. 6256.

5
[ 58755-91-2 ]
[ 107-11-9 ]
[ 73923-84-9 ]

References: [1]Journal of the American Chemical Society,1953,vol. 75,p. 6256.

6
[ 58755-91-2 ]
[ 74-89-5 ]
[ 1628-20-2 ]

References: [1]Journal of the American Chemical Society,1953,vol. 75,p. 6256.

7
[ 108-31-6 ]
[ 673-41-6 ]
[ 58755-91-2 ]

References: [1]Synthesis,1986,p. 308 - 309.

8
[ 4005-51-0 ]
[ 58755-91-2 ]
[ 139477-23-9 ]