[ CAS No. 630-19-3 ] {[proInfo.proName]}

Name: 630-19-3|Pivalaldehyde|96% GC
Brand: Ambeed
SKU: A858364
Rating: 99 (32 reviews)

,{[proInfo.pro_purity]}

Cat. No.: {[proInfo.prAm]}

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Inaccessible (Haz class 6.1), International	USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic	USD 100+
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3d Animation Molecule Structure of 630-19-3

Structure of 630-19-3 * Storage: {[proInfo.prStorage]}

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Quality Control of [ 630-19-3 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 630-19-3 ]

SDS Specification

Alternatived Products of [ 630-19-3 ]

Product Details of [ 630-19-3 ]

CAS No. :	630-19-3	MDL No. :	MFCD00006962
Formula :	C₅H₁₀O	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	FJJYHTVHBVXEEQ-UHFFFAOYSA-N
M.W :	86.13	Pubchem ID :	12417
Synonyms :

Calculated chemistry of [ 630-19-3 ]

Physicochemical Properties

Num. heavy atoms :	6
Num. arom. heavy atoms :	0
Fraction Csp3 :	0.8
Num. rotatable bonds :	1
Num. H-bond acceptors :	1.0
Num. H-bond donors :	0.0
Molar Refractivity :	26.09
TPSA :	17.07 Å²

Pharmacokinetics

GI absorption :	High
BBB permeant :	Yes
P-gp substrate :	No
CYP1A2 inhibitor :	No
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	No
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-6.02 cm/s

Lipophilicity

Log Po/w (iLOGP) :	1.5
Log Po/w (XLOGP3) :	1.13
Log Po/w (WLOGP) :	1.23
Log Po/w (MLOGP) :	1.01
Log Po/w (SILICOS-IT) :	0.83
Consensus Log Po/w :	1.14

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	2.0
Bioavailability Score :	0.55

Water Solubility

Log S (ESOL) :	-1.02
Solubility :	8.23 mg/ml ; 0.0955 mol/l
Class :	Very soluble
Log S (Ali) :	-1.08
Solubility :	7.13 mg/ml ; 0.0827 mol/l
Class :	Very soluble
Log S (SILICOS-IT) :	-0.93
Solubility :	10.0 mg/ml ; 0.117 mol/l
Class :	Soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	1.0 alert
Leadlikeness :	1.0
Synthetic accessibility :	1.0

Safety of [ 630-19-3 ]

Signal Word:	Danger	Class:	3
Precautionary Statements:	P210-P233-P240-P241+P242+P243-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501	UN#:	1989
Hazard Statements:	H225-H315-H319	Packing Group:	Ⅱ
GHS Pictogram:

Application In Synthesis of [ 630-19-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 630-19-3 ]
Downstream synthetic route of [ 630-19-3 ]

[ 630-19-3 ] Synthesis Path-Upstream 1~22

1
[ 1310816-15-9 ]
[ 630-19-3 ]
[ 1120-90-7 ]
[ 1210053-16-9 ]

Reference： [1] Heterocycles, 2011, vol. 83, # 4, p. 837 - 847

2
[ 1203646-03-0 ]
[ 630-19-3 ]
[ 612-61-3 ]
[ 1310816-16-0 ]

Reference： [1] Heterocycles, 2011, vol. 83, # 4, p. 837 - 847

3
[ 630-19-3 ]
[ 69741-92-0 ]

Reference： [1] Journal of Organic Chemistry, 2015, vol. 80, # 2, p. 1018 - 1024

4
[ 630-19-3 ]
[ 3282-30-2 ]

Reference： [1] Organic Letters, 2015, vol. 17, # 15, p. 3666 - 3669
[2] New Journal of Chemistry, 2017, vol. 41, # 3, p. 931 - 939
[3] Tetrahedron Letters, 2017, vol. 58, # 26, p. 2533 - 2536

5
[ 131543-46-9 ]
[ 630-19-3 ]
[ 36947-69-0 ]

Reference： [1] Patent: US2011/52578, 2011, A1,
[2] Patent: US2013/210818, 2013, A1, . Location in patent: Paragraph 0332
[3] European Journal of Medicinal Chemistry, 2016, vol. 108, p. 605 - 615
[4] Patent: WO2009/115572, 2009, A2, . Location in patent: Page/Page column 99

6
[ 866-23-9 ]
[ 630-19-3 ]
[ 3167-63-3 ]
[ 32363-94-3 ]

Reference： [1] Recueil: Journal of the Royal Netherlands Chemical Society, 1980, vol. 99, # 6, p. 202 - 206

7
[ 630-19-3 ]
[ 33105-81-6 ]

Reference： [1] Tetrahedron Letters, 1994, vol. 35, # 16, p. 2459 - 2462

8
[ 630-19-3 ]
[ 20859-02-3 ]

Reference： [1] Helvetica Chimica Acta, 1980, vol. 63, # 4, p. 824 - 831
[2] Journal of Organic Chemistry, 1989, vol. 54, # 5, p. 1055 - 1062
[3] Patent: CN104193629, 2016, B,

9
[ 630-19-3 ]
[ 20859-02-3 ]

Reference： [1] Nature, 2009, vol. 461, # 7266, p. 968 - 970

10
[ 630-19-3 ]
[ 754-10-9 ]

Reference： [1] Journal of Organic Chemistry, 2003, vol. 68, # 3, p. 1158 - 1160

11
[ 630-19-3 ]
[ 2041-37-4 ]

Reference： [1] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993, # 1, p. 111 - 116

12
[ 630-19-3 ]
[ 61501-04-0 ]

Reference： [1] Synthetic Communications, 1994, vol. 24, # 20, p. 2955 - 2972

13
[ 106-47-8 ]
[ 630-19-3 ]
[ 65854-91-3 ]

Reference： [1] ACS Catalysis, 2016, vol. 6, # 12,

14
[ 455-14-1 ]
[ 630-19-3 ]
[ 25617-34-9 ]

Reference： [1] ACS Catalysis, 2016, vol. 6, # 12,

15
[ 630-19-3 ]
[ 74181-34-3 ]
[ 81286-82-0 ]

Reference： [1] Tetrahedron Letters, 2016, vol. 57, # 47, p. 5254 - 5258

16
[ 3027-05-2 ]
[ 630-19-3 ]
[ 3060-50-2 ]
[ 119-61-9 ]
[ 57224-50-7 ]
[ 88319-43-1 ]

Reference： [1] Tetrahedron Letters, 2016, vol. 57, # 41, p. 4612 - 4615

17
[ 630-19-3 ]
[ 124655-17-0 ]

Reference： [1] Patent: US2013/66109, 2013, A1,
[2] Patent: US2013/66109, 2013, A1,

18
[ 630-19-3 ]
[ 88319-43-1 ]

Reference： [1] Journal of the Chemical Society, Chemical Communications, 1994, # 17, p. 1915 - 1916

19
[ 3027-05-2 ]
[ 630-19-3 ]
[ 3060-50-2 ]
[ 119-61-9 ]
[ 57224-50-7 ]
[ 88319-43-1 ]

Reference： [1] Tetrahedron Letters, 2016, vol. 57, # 41, p. 4612 - 4615

20
[ 630-19-3 ]
[ 1214741-19-1 ]

Reference： [1] Patent: US2014/31549, 2014, A1,
[2] Organic Letters, 2018, vol. 20, # 6, p. 1509 - 1512

21
[ 630-19-3 ]
[ 1214741-20-4 ]

Reference： [1] Patent: US2014/31549, 2014, A1,

22
[ 630-19-3 ]
[ 1214741-21-5 ]

Reference： [1] Patent: US2014/31549, 2014, A1,

[ 630-19-3 ] Synthesis Path-Downstream 1~88

1
[ 42826-42-6 ]
[ 630-19-3 ]

Reference： [1]Journal of the Chemical Society. Chemical communications,1982,p. 450 - 452
[2]Journal of the Chemical Society. Chemical communications,1982,p. 450 - 452

2
[ 138286-76-7 ]
[ 108-24-7 ]
[ 630-19-3 ]
[ 128850-01-1 ]

Reference： [1]Tetrahedron Letters,1989,vol. 30,p. 7373 - 7376

3
[ 625-72-9 ]
[ 630-19-3 ]
[ 100017-18-3 ]

Reference： [1]Helvetica Chimica Acta,1986,vol. 69,p. 1147 - 1152
[2]Helvetica Chimica Acta,1987,vol. 70,p. 448 - 464

4
[ 625-72-9 ]
[ 630-19-3 ]
[ 100017-18-3 ]
[ 51288-15-4 ]

Reference： [1]Angewandte Chemie,1986,vol. 98,p. 182 - 183
[2]European Journal of Organic Chemistry,2015,vol. 2015,p. 647 - 654

5
[ 3347-90-8 ]
[ 630-19-3 ]
[ 115860-93-0 ]

Reference： [1]Liebigs Annalen der Chemie,1988,p. 949 - 954

6
[ 1187-84-4 ]
[ 630-19-3 ]
(R)-2-tert-Butyl-4-methylsulfanylmethyl-oxazolidin-5-one [ No CAS ]

Reference： [1]Australian Journal of Chemistry,1993,vol. 46,p. 73 - 93
[2]Chemical Communications,2000,p. 2131 - 2132

7
[ 42826-42-6 ]
[ 630-19-3 ]
[ 77637-83-3 ]

Reference： [1]Chemische Berichte,1981,vol. 114,p. 802 - 807

8
[ 3027-13-2 ]
[ 630-19-3 ]
[ 76106-55-3 ]

Reference： [1]Journal of the Chemical Society. Perkin transactions I,1980,p. 1555 - 1566

9
[ 21209-51-8 ]
[ 630-19-3 ]
benzyl (2R,4S)-3-<(benzyloxy)carbonyl>-2-(tert-butyl)oxazolidine-4-carboxylate [ No CAS ]
benzyl (2S,4S)-3-<(benzyloxy)carbonyl>-2-(tert-butyl)oxazolidine-4-carboxylate [ No CAS ]

Reference： [1]Helvetica Chimica Acta,1994,vol. 77,p. 1313 - 1330

10
[ 57224-63-2 ]
[ 630-19-3 ]
methyl (2S,4S,5R)-3-<(benzyloxy)carbonyl>-2-(tert-butyl)-5-methyloxazolidine-4-carboxylate [ No CAS ]
methyl (2R,4S,5R)-3-<(benzyloxy)carbonyl>-2-(tert-butyl)-5-methyloxazolidine-4-carboxylate [ No CAS ]

Reference： [1]Helvetica Chimica Acta,1994,vol. 77,p. 1313 - 1330
[2]Helvetica Chimica Acta,1994,vol. 77,p. 1313 - 1330

11
[ 7768-28-7 ]
[ 630-19-3 ]
[ 93953-88-9 ]

Reference： [1]Canadian Journal of Chemistry,1984,vol. 62,p. 2830 - 2840

12
[ 14799-82-7 ]
[ 630-19-3 ]
[ 135640-92-5 ]

Reference： [1]Bulletin of the Chemical Society of Japan,1991,vol. 64,p. 1454 - 1460

13
[ 630-19-3 ]
[ 22356-89-4 ]
N-(2',2'-Dimethylpropyliden)glycin-(N-methylamid) [ No CAS ]

Reference： [1]Helvetica Chimica Acta,1985,vol. 68,p. 135 - 143

14
[ 42826-42-6 ]
[ 74-88-4 ]
[ 75-97-8 ]
[ 630-19-3 ]

Reference： [1]Journal of the Chemical Society. Chemical communications,1982,p. 450 - 452

15
[ 1184-88-9 ]
[ 630-19-3 ]

Reference： [1]Heterocycles,1988,vol. 27,p. 1595 - 1598

16
[ 53662-85-4 ]
[ 630-19-3 ]
3-(1-Hydroxy-2,2-dimethyl-propyl)-tetrahydro-furan-3-carboxylic acid methyl ester [ No CAS ]
3-(2-Oxo-tetrahydro-furan-3-ylmethyl)-tetrahydro-furan-3-carboxylic acid methyl ester [ No CAS ]

Reference： [1]Tetrahedron Letters,1995,vol. 36,p. 2641 - 2644

17
[ 6627-78-7 ]
[ 630-19-3 ]
2,2-Dimethyl-1-(4-methyl-naphthalen-1-yl)-propan-1-ol [ No CAS ]

Reference： [1]Journal of the American Chemical Society,1995,vol. 117,p. 6686 - 6690

18
[ 767-60-2 ]
[ 630-19-3 ]
2,2-Dimethyl-1-((S)-3-methyl-1H-inden-1-yl)-propan-1-ol [ No CAS ]
2,2-Dimethyl-1-((R)-1-methyl-1H-inden-1-yl)-propan-1-ol [ No CAS ]

Reference： [1]Angewandte Chemie,1995,vol. 107,p. 2328 - 2330

19
[ 2462-35-3 ]
[ 630-19-3 ]
(S)-2-[2,2-Dimethyl-prop-(E)-ylideneamino]-4-methyl-pentanoic acid benzyl ester [ No CAS ]

Reference： [1]Synthesis,1998,p. 297 - 300

20
[ 5557-81-3 ]
[ 630-19-3 ]
(S)-2-[2,2-Dimethyl-prop-(E)-ylideneamino]-propionic acid benzyl ester [ No CAS ]

Reference： [1]Synthesis,1998,p. 297 - 300

21
[ 119072-55-8 ]
[ 630-19-3 ]
[ 185836-75-3 ]
(R)-N-(1-tert-Butylcarbamoyl-2,2-dimethyl-propyl)-3-methyl-succinamic acid tert-butyl ester [ No CAS ]

Reference： [1]Synlett,1998,p. 637 - 639

22
[ 630-19-3 ]
[ 72784-42-0 ]
1-[2,2-Dimethyl-prop-(E)-ylideneamino]-cyclopropanecarboxylic acid methyl ester [ No CAS ]

Reference： [1]Il Farmaco,1998,vol. 53,p. 181 - 188

23
[ 3775-72-2 ]
[ 630-19-3 ]
(S)-2-tert-Butyl-6-methyl-tetrahydro-pyrimidin-4-one [ No CAS ]

Reference： [1]European Journal of Organic Chemistry,1999,p. 335 - 360

24
[ 1152-62-1 ]
[ 630-19-3 ]
[ 501-53-1 ]
[ 245107-59-9 ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,1999,vol. 9,p. 1907 - 1910

25
[ 6168-83-8 ]
[ 630-19-3 ]
(2S,6S)-2-tert-Butyl-6-methyl-[1,3]dioxan-4-one [ No CAS ]

Reference： [1]Chemistry - A European Journal,1999,vol. 5,p. 3221 - 3236

26
[ 95-89-6 ]
[ 630-19-3 ]
2,2-dimethyl-1-(3,6-dimethylpyrazyl)propanol [ No CAS ]

Reference： [1]Tetrahedron,2000,vol. 56,p. 4043 - 4052

27
[ 1532-71-4 ]
[ 630-19-3 ]
2,2-dimethyl-1-(1-isoquinolinyl)-1-propanol [ No CAS ]

Reference： [1]Tetrahedron,2001,vol. 57,p. 2133 - 2138

28
[ 630-19-3 ]
[ 144978-12-1 ]
4-(1-hydroxy-2,2-dimethyl-propyl)-5-oxo-pyrrolidine-1,2-dicarboxylic acid 1-<i>tert</i>-butyl ester 2-ethyl ester [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry,2001,vol. 9,p. 875 - 879

29
[ 1187-84-4 ]
[ 630-19-3 ]
Sodium; (R)-2-[2,2-dimethyl-prop-(Z)-ylideneamino]-3-methylsulfanyl-propionate [ No CAS ]

Reference： [1]Tetrahedron,2001,vol. 57,p. 6539 - 6556

30
[ 700-63-0 ]
[ 630-19-3 ]
(R)-2-[2,2-Dimethyl-prop-(E)-ylideneamino]-2-phenyl-acetamide [ No CAS ]

Reference： [1]Organic Letters,2001,vol. 3,p. 3943 - 3946

31
[ 3068-00-6 ]
[ 630-19-3 ]
(+/-)-cis-(2-tert-butyl-1,3-dioxan-4-yl)methanol [ No CAS ]
(+/-)-trans-2-(2-tert-butyl-1,3-dioxolan-4-yl)-ethan-1-ol [ No CAS ]
(+/-)-cis-2-(2-tert-butyl-1,3-dioxolan-4-yl)-ethan-1-ol [ No CAS ]

Reference： [1]Synthesis,2004,p. 1033 - 1036

32
[ 630-22-8 ]
[ 630-19-3 ]
2,4,6-tri-tert-butyl-6H-1,3,5-oxathiazine [ No CAS ]

Reference： [1]Heteroatom Chemistry,2004,vol. 15,p. 175 - 186

33
[ 2346-00-1 ]
[ 630-19-3 ]
4,5-dihydro-2-[(E)-3,3-dimethyl-1-butenyl]-1,3-thiazole [ No CAS ]

Reference： [1]European Journal of Organic Chemistry,2005,p. 3791 - 3800

34
[ 700-63-0 ]
[ 143-33-9 ]
[ 630-19-3 ]
[ 340291-70-5 ]

Reference： [1]Organic Letters,2001,vol. 3,p. 1121 - 1124

35
[ 3347-90-8 ]
[ 630-19-3 ]
(2R,5S)-2-tert-butyl-5-ethyl-[1,3]dioxolan-4-one [ No CAS ]
[ 115860-93-0 ]

Reference： [1]Tetrahedron,2006,vol. 62,p. 4153 - 4161
[2]Heterocycles,2007,vol. 72,p. 255 - 273

36
[ 13737-04-7 ]
[ 630-19-3 ]
[ 20609-11-4 ]

Reference： [1]Chemical Communications,2006,p. 4850 - 4852

37
[ 630-19-3 ]
[ 136-90-3 ]
(2,2-dimethyl-propylidene)-(4-methoxy-3-methyl-phenyl)-amine [ No CAS ]

Reference： [1]Journal of the American Chemical Society,2007,vol. 129,p. 1978 - 1986

38
[ 630-19-3 ]
[ 4269-94-7 ]
6-(1-hydroxy-2,2-dimethylpropyl)pyrimidine-2,4(1H,3H)-dione [ No CAS ]

Reference： [1]Organic Letters,2007,vol. 9,p. 1639 - 1641

39
[ 71759-89-2 ]
[ 630-19-3 ]
C₈H₁₄N₂O [ No CAS ]

Reference： [1]Synlett,2007,p. 980 - 982

40
[ 15813-09-9 ]
[ 630-19-3 ]
C₈H₁₃IN₂O [ No CAS ]

Reference： [1]Synlett,2007,p. 980 - 982

41
[ 3347-90-8 ]
[ 630-19-3 ]
[ 106-95-6 ]
(2R,5R)-5-allyl-2-tert-butyl-5-ethyl-[1,3]dioxolan-4-one [ No CAS ]
[ 115860-94-1 ]

Reference： [1]Heterocycles,2007,vol. 72,p. 255 - 273

42
[ 630-19-3 ]
[ 33105-81-6 ]

Reference： [1]Tetrahedron Letters,1994,vol. 35,p. 2459 - 2462

43
[ 74-90-8 ]
[ 630-19-3 ]
[ 17672-22-9 ]
2,2-dimethyl-1-(2-hydroxy-6-methylphenyl)aminopropane-1-carbonitrile [ No CAS ]

Reference： [1]Patent: US6339159,2002,B1 .Location in patent: Example 2
[2]Patent: US6339159,2002,B1 .Location in patent: Example 2

44
[ 700-63-0 ]
[ 630-19-3 ]
(R)-2-(2,2-Dimethyl-propylamino)-2-phenyl-acetamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
97%		D-(-)-2-Amino-2-phenyl-acetamide (1.0 g, 6.7 mmol) was partially dissolved in 20 ml dichloromethane and treated with trimethylacetaldehyde (723 uL, 6.7 mmol). After stirring 20 min at room temperature, sodium triacetoxyborohydride (1.77 g, 8.4 mmol) was added and the resulting mixture was stirred at room temperature (rt) for 18 h. After diluting with aqueous sodium bicarbonate, the mixture was extracted with dichloromethane. The combined organics were dried (Na2SO4) and concentrated to a white solid (1.43 g, 97percent yield). MS 221.2 m/z (M+1).

Reference： [1]Patent: US2005/222254,2005,A1 .Location in patent: Page/Page column 18

45
[ 2899-37-8 ]
[ 630-19-3 ]
C₁₀H₂₁NOS [ No CAS ]

Reference： [1]Chemical Communications,2006,p. 2983 - 2985

46
[ 630-19-3 ]
[ 144222-34-4 ]
[ 1043450-06-1 ]

Reference： [1]Tetrahedron Asymmetry,2008,vol. 19,p. 1250 - 1255

47
[ 3068-00-6 ]
[ 630-19-3 ]
[ 1115323-44-8 ]
(+/-)-cis-(2-tert-butyl-1,3-dioxan-4-yl)methanol [ No CAS ]

Reference： [1]European Journal of Organic Chemistry,2008,p. 6015 - 6028

48
[ 74472-22-3 ]
[ 630-19-3 ]
C₁₃H₂₈OSi [ No CAS ]

Reference： [1]Tetrahedron Letters,2009,vol. 50,p. 2967 - 2969

49
[ 50595-15-8 ]
[ 630-19-3 ]
tert-butyl 2,3-dihydroxy-4,4-dimethylpentanoate [ No CAS ]

Reference： [1]Journal of Organic Chemistry,2009,vol. 74,p. 1788 - 1790

50
[ 50595-15-8 ]
[ 630-19-3 ]
tert-butyl 2,3-dihydroxy-4,4-dimethylpentanoate [ No CAS ]
C₁₁H₂₂O₄ [ No CAS ]

Reference： [1]Journal of Organic Chemistry,2009,vol. 74,p. 1788 - 1790

51
[ 90560-10-4 ]
[ 630-19-3 ]
[ 1001203-35-5 ]

Yield	Reaction Conditions	Operation in experiment
72%		EXAMPLE 3Preparation of 2-(2,2-dimethylpropyl)-1,1-dioxo-1H-lambda6-benzo[b]thiophen-6-ylsulfamoyl ester; 5.44 ml of a 15percent butyllithium solution in tetrahydrofuran (8.67 mmol) are slowly added at -60° C. under argon to a clear solution of 1.294 g (7.88 mmol) of unit 2 in 20 ml of tetrahydrofuran. The mixture is stirred for a further 1.5 h. 747 mg of 2,2-dimethylpropionaldehyde are subsequently added at -50° C. under argon. The clear solution is allowed to come to room temperature over the course of 1 h, stirring is continued overnight, and hydrochloric acid (1 N) is slowly added to pH 1. The phases are separated, and the aqueous phase is extracted with dichloromethane. The organic phases are combined, washed with a saturated sodium chloride solution and with a saturated sodium hydrogencarbonate solution, dried using sodium sulfate, filtered and evaporated. The crystallised residue is digested with petroleum ether and filtered off with suction, giving white crystals (1.44 g, 72percent yield), which can be identified as 17a.1H NMR (250 MHz, DMSO-d6) 0.93 (s, 9H), 3.8 (s, 3H), 4.5 (d, 1H), 5.7 (d, 1H), 6.93 (dd, 1H), 7.09 (s, 1H), 7.45 (d, 1H), 7.62 (d, 1H).

Reference： [1]Patent: US2009/286863,2009,A1 .Location in patent: Page/Page column 12

52
[ 13423-60-4 ]
[ 630-19-3 ]
[ 1193686-46-2 ]

Reference： [1]Journal of Organic Chemistry,2009,vol. 74,p. 8309 - 8313

53
[ 95-14-7 ]
[ 6343-93-7 ]
[ 630-19-3 ]
[ 861393-67-1 ]

Reference： [1]Journal of Medicinal Chemistry,2009,vol. 52,p. 3366 - 3376

54
[ 1187-84-4 ]
[ 630-19-3 ]
C₉H₁₇NO₂S [ No CAS ]

Reference： [1]Organic and Biomolecular Chemistry,2010,vol. 8,p. 5120 - 5125

55
[ 74472-22-3 ]
[ 630-19-3 ]
[ 1162681-67-5 ]

Yield	Reaction Conditions	Operation in experiment
87%	With Al-MCM-41 (Si/Al = 26); In dichloromethane; at 30℃; for 1h;Inert atmosphere;	General procedure: Under an atmosphere of argon, to a mixture of benzaldehyde (0.106 g, 1.0 mmol) and Al-MCM-41 (30 mg, Si/Al=26, dried prior to use at 120 C for 1 h under vacuum) in dichloromethane (1.5 mL), allyltrimethylsilane (0.172 g, 1.5 mmol) in dichloromethane (0.5 mL) was added through a syringe at 30 C. The reaction mixture was stirred at 30 C for 1 h. The catalyst was removed by filtration and washed with dichloromethane (40 mL). After the filtrate was concentrated under reduced pressure, crude product was purified by silica-gel column chromatography (hexane/Et2O=20:1) to afford 4-trimethylsiloxy-4-phenyl-1-butene25 as a colorless oil (0.203 g, 92%).

Reference： [1]Tetrahedron,2011,vol. 67,p. 2081 - 2089

56
[ 1203646-03-0 ]
[ 630-19-3 ]
[ 612-61-3 ]
[ 1310816-16-0 ]

Reference： [1]Heterocycles,2011,vol. 83,p. 837 - 847

57
[ 630-19-3 ]
[ 22356-89-4 ]
[ 101055-55-4 ]

Yield	Reaction Conditions	Operation in experiment
55%	With ytterbium(III) triflate; In chloroform; for 8h;Reflux;	General procedure: Recrystallised amino amide (1 equiv), aldehyde/ketone (2 equiv) and ytterbium trifluromethane sulfonate (0.01 equiv) were refluxed in chloroform (10 mL/mmol amino amide) for 8 h after which time the mixture was allowed to cool and the solvent evaporated. The products were purified by column chromatography.

Reference： [1]Tetrahedron,2011,vol. 67,p. 4263 - 4267

58
[ 630-19-3 ]
[ 2043-61-0 ]
[ 5340-26-1 ]
[ 86328-69-0 ]
[ 2611-02-1 ]
neopentyl cyclohexanecarboxylate [ No CAS ]

Reference： [1]Journal of the American Chemical Society,2011,vol. 133,p. 4668 - 4671

59
[ 214279-40-0 ]
[ 630-19-3 ]
[ 1372854-34-6 ]

Yield	Reaction Conditions	Operation in experiment
88%		To a solution of <strong>[214279-40-0]3-iodo-4-nitroanisol</strong>e (2.79 g, 10.0 mmol) in anhydrous THF (10 mL) at minus 40C under a nitrogen atmosphere, phenylmagnesium chloride (2 M in THF, 4.2 mL, 8.3 mmol) was added dropwise at a rate such that the temperature would not exceed minus 35C. Upon completion of the addition, the mixture was stirred at minus 40C for two hours, followed by addition of trimethylacetaldehyde (1.1 mL, 10 mmol). The mixture was stirred at minus 40C for two hours and then at room temperature for another one hour. The reaction was then quenched with brine (100 mL), and the mixture was extracted with CH2CI2 (40 mL) three times. The combined organic phase was dried over Na2S04, concentrated in vacuo, and the residue was purified by silica gel column chromatography to yield racemic (R/S)-l -(5-methoxy-2-nitrophenyl)-2,2-dimethyl- l-propanol (1.76 g, 88%). 1H NMR (400 MHz, CDCk): delta 7.89 (d, 1 H, J = 9.2 Hz, Ph-H), 7.27 (d, 1 H, J = 2.8 Hz, Ph-H), 6.84 (dd, 1 H, J= 8.8 and 2.8 Hz, Ph-H), 5.62 (d, 1 H, J= 4.0 Hz, PhCH), 3.89 (s, 3 H, OCH3), 2.08 (d, 1 H, J= 4.0 Hz, OH), 0.89 (s, 9 H, C(CH3)3).

Reference： [1]Angewandte Chemie - International Edition,2012,vol. 51,p. 1724 - 1727
[2]Patent: WO2013/40257,2013,A1 .Location in patent: Page/Page column 89; 90

60
[ 700-63-0 ]
[ 630-19-3 ]
[ 115276-56-7 ]

Reference： [1]Journal of labelled compounds and radiopharmaceuticals,2012,vol. 55,p. 108 - 114

61
[ 19056-41-8 ]
[ 1268385-83-6 ]
[ 630-19-3 ]
[ 1408193-99-6 ]

Reference： [1]Chemistry - A European Journal,2012,vol. 18,p. 12624 - 12627

62
[ 19056-41-8 ]
[ 1268385-83-6 ]
[ 630-19-3 ]
3-bromo-N-(1-(5-ethoxy-4-(4-nitrophenyl)oxazol-2-yl)-2,2-dimethylpropyl)-4-methoxyaniline [ No CAS ]

Reference： [1]Chemistry - A European Journal,2012,vol. 18,p. 12624 - 12627

63
[ 19056-41-8 ]
[ 1268385-83-6 ]
[ 102-92-1 ]
[ 630-19-3 ]
[ 1408194-23-9 ]

Reference： [1]Chemistry - A European Journal,2012,vol. 18,p. 12624 - 12627

64
[ 66130-92-5 ]
[ 19056-41-8 ]
[ 1268385-83-6 ]
[ 630-19-3 ]
[ 1408194-24-0 ]

Reference： [1]Chemistry - A European Journal,2012,vol. 18,p. 12624 - 12627

65
[ 630-19-3 ]
[ 161609-76-3 ]
C₁₆H₂₅NO [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2013,vol. 23,p. 6825 - 6828

66
[ 630-19-3 ]
[ 1214741-20-4 ]

Reference： [1]Patent: US2014/31549,2014,A1

67
[ 630-19-3 ]
[ 428854-24-4 ]
[ 1361570-58-2 ]

Yield	Reaction Conditions	Operation in experiment
		Example 64A N5-(2,2-Dimethylpropyl)-<strong>[428854-24-4]2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5,6-triamine</strong> 500 mg (1.43 mmol) of the compound from example 1A were added to a solution of methanol (20.0 ml) and 180 mul of acetic acid, then 349 mul (3.14 mmol) of pivalaldehyde were added and the mixture was stirred at RT for 15 min. Then 251 mg (4.00 mmol) of sodium cyanoborohydride were added and the reaction mixture was stirred further at RT overnight. Then a further 349 mul of pivalaldehyde, 180 mul of acetic acid and 251 mg of sodium cyanoborohydride were added to the reaction mixture and stirring of the mixture at RT continued overnight. Thereafter, another 349 of pivalaldehyde, 180 mul of acetic acid and 251 mg of sodium cyanoborohydride were added and the mixture was stirred further at RT overnight. Subsequently, saturated aqueous sodium hydrogencarbonate solution were added and the mixture was stirred for a further 30 min. Thereafter, the mixture was concentrated and the residue was taken up in ethyl acetate. The organic phase was washed twice with water and once with saturated aqueous sodium chloride solution, dried over sodium sulfate, filtered and concentrated. The residue was stirred with tert-butyl methyl ether, filtered, washed with tert-butyl methyl ether and then dried under high vacuum. This gave 447 mg (88% purity, 66% of theory) of the title compound, which were converted without further purification. LC-MS (method 2): Rt=0.96 min MS (EIpos): m/z=421 (M+H)+. 1H NMR (400 MHz, DMSO-d6): delta [ppm]=0.96 (s, 9H), 3.30 (s, 2H), 5.78 (s, 2H), 5.97 (s, 4H), 7.10-7.15 (m, 2H), 7.19-7.26 (m, 1H), 7.30-7.39 (m, 2H), 8.57-8.61 (m, 1H), 9.02-9.07 (m, 1H).

Reference： [1]Patent: US2014/148433,2014,A1 .Location in patent: Paragraph 0864; 0865; 0866

68
[ 6168-83-8 ]
[ 630-19-3 ]
C₉H₁₆O₃ [ No CAS ]
(2S,6S)-2-tert-Butyl-6-methyl-[1,3]dioxan-4-one [ No CAS ]

Reference： [1]European Journal of Organic Chemistry,2015,vol. 2015,p. 647 - 654

69
[ 71811-26-2 ]
[ 630-19-3 ]
benzyl (2-(tert-butyl)-1,3-dioxan-5-yl)carbamate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With magnesium sulfate; toluene-4-sulfonic acid; In tetrahydrofuran;Reflux;	A mixture of benzyl (1 ,3-dihydroxypropan-2-yl)carbamate (1.12 g, 4.98 mmol), trimethylacetaldehyde (1.03 mL, 9.48 mmol), toluenesulphonic acid monohydrate (52 mg, 0.27 mmol) and anhydrous magnesium sulphate (2.4 g, 20 mmol) in anhydrous THF (15 mL) was heated under reflux overnight. The mixture was cooled, treated with aqueous NaHC03 (20 mL) and stirred until effervescence ceased. The phases were separated and the aqueous phase was extracted with diethyl ether (3 x 20 mL). The combined organic phases were washed with water and brine, dried (MgS04), filtered and concentrated. The afforded oil was triturated with petroleum ether 40-60 and the resulting suspension was extracted with petroleum ether (3 x 50 mL) and filtered. The filtrate was concentrated, which gave the title compound as a -1 :1 mixture of cis and trans isomers. The mixture was used in the next step without further purification. 1H NMR (500 MHz, CDCI3) delta 7.37 (m, 5H), 5.66 (d, J = 9.2 Hz, 0.5H), 5.17-5.10 (m, 2.5H), 4.56 (m, 0.5H), 4.22 (m, 1 H), 4.16 (s, 0.5H), 4.00 (m, 1.5H), 3.89 (m, 1 H), 3.64 (m, 0.5H), 3.30 (m, 1 H), 0.93 (s, 9H).

Reference： [1]Patent: WO2015/189595,2015,A1 .Location in patent: Page/Page column 28

70
[ 931-53-3 ]
[ 704-14-3 ]
[ 630-19-3 ]
N-cyclohexyl-2-(5-methoxy-2-nitrophenoxy)-3,3-dimethylbutanamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
68%	With 1,4-diaza-bicyclo[2.2.2]octane; In neat (no solvent); at 55℃; for 12h;	General procedure: To 1.0 equiv. of phenol were added successively 1.0 equiv. of DABCO, 2.0 equiv. of aldehyde and 1.0 equiv. of isocyanide. The resulting mixture was stirred neat at 55 C for 12 h. The crude product was purified by flash chromatography on silica gel.

Reference： [1]Molecules,2016,vol. 21

71
[ 17288-15-2 ]
[ 630-19-3 ]
C₁₁H₂₁NO₂ [ No CAS ]

Reference： [1]ChemBioChem,2017,vol. 18,p. 300 - 315

72
[ 630-19-3 ]
[ 182223-54-7 ]
benzyl (1-neo-pentylpiperidin-4-yl)carbamate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
900 mg		General procedure: To a solution of compound I-4 (470 mg, 1.47 mmol) in DCM, TFA (2.5 mL, 29 mmol) was addedand then the reaction mixture was stirred at room temperature for 2 h and then was evaporated togive the crude product directly used in the next step A mixture of the amine, DIEA (3.84 mL,22.05mmol) and cyclohexanone (1.5 mL) in THF (10 mL) was stirred at room temperature for 1.5h and then NaBH(OAc)3 (1.6 g, 7.35 mmol) was added into the solution. The reaction mixture wasstirred at room temperature for overnight and then H2O was added to quench the reaction. Thesolution was extracted with ethyl acetate (30 mL × 2). The organic layer was washed with brine(15 mL × 2) and then was dried over anhydrous MgSO4. After filtration and concentration, thecrude product I-5 was obtained and purified with column chromatography ( methylene chloride/methanol = 45:1 to 30:1) to give compound I-5 as light yellow oil (350 mg, 78%).

Reference： [1]European Journal of Medicinal Chemistry,2017,vol. 132,p. 26 - 41

73
[ 75-97-8 ]
[ 630-19-3 ]
[ 67-64-1 ]
[ 1138-52-9 ]

Reference： [1]Chemistry - A European Journal,2017,vol. 23,p. 8596 - 8600

74
[ 2899-28-7 ]
[ 630-19-3 ]
ethyl neopentyl-L-tryptophanate [ No CAS ]

Reference： [1]Angewandte Chemie - International Edition,2017,vol. 56,p. 11958 - 11962
Angew. Chem.,2017,vol. 129,p. 12120 - 12124,5

75
[ 18822-58-7 ]
[ 630-19-3 ]
C₁₂H₂₂NO₃^(1-)*Na⁽¹⁺⁾ [ No CAS ]

Reference： [1]Chemical Science,2017,vol. 8,p. 7368 - 7373

76
[ 4727-00-8 ]
[ 630-19-3 ]
C₁₈H₂₆NO₃^(1-)*Na⁽¹⁺⁾ [ No CAS ]

Reference： [1]Chemical Science,2017,vol. 8,p. 7368 - 7373

77
[ 29312-98-9 ]
[ 630-19-3 ]
C₁₁H₁₆FNO [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
77%	With n-butyllithium; In hexane;	Example 8 6-Fluoro-5-methyl-3-pyridinemethanol: alpha-(1,1-dimethylethyl)-, 5-Bromo-2-fluoro-3-methylpyridine (2.0 g, 0.011 mol) was dissolved with stirring in anhydrous ether (30 mL) and cooled to -70 C. This was treated at <-60 C. with n-butyl lithium (4.8 mL, 2.5M in hexane, 0.012 mol) and the reaction mixture stirred at <-70 C. for one hour. Trimethylacetaldehyde (1.14 g, 0.013 mol) was added and the reaction mixture allowed to warm to -10 C. The reaction mixture was quenched with ammonium chloride solution and extracted with ethyl acetate. The organic extract was washed with water and brine, dried (Na2SO4) and evaporated to dryness. Purification of the residue by chromatography over silica (5-25% ethyl acetate:hexane) gave the desired product (1.6 g, 77%) as a clear oil.

Reference： [1]Patent: US6211202,2001,B1

78
[ 550-24-3 ]
[ 630-19-3 ]
[ 109-77-3 ]
2-amino-4-(tert-butyl)-6-hydroxy-5,8-dioxo-7-undecyl-5,8-dihydro-4H-chromene-3-carbonitrile [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
41%	With triethylamine; In ethanol; for 8h;Reflux;	General procedure: To a mixture of 0.1mmol of malononitrile, 0.1mmol of the corresponding aldehyde, and 10mol % of Et3N in 5mL of EtOH were added 30mg of <strong>[550-24-3]embelin</strong> (0.1mmol). The reaction mixture was stirred and refluxed until disappearance of the starting benzoquinone. The solvent was removed under vacuum, and the crude product was purified by preparative-TLC to yield the corresponding dihydropyran derivative.

Reference： [1]European Journal of Medicinal Chemistry,2018,vol. 144,p. 410 - 423

79
[ 5714-80-7 ]
[ 630-19-3 ]
[ 166516-86-5 ]

Reference： [1]Tetrahedron,2018,vol. 74,p. 549 - 555

80
[ 1060805-69-7 ]
[ 630-19-3 ]
4,4′′-dibromo-4’-(tert-butyl)-2,2′:6′,2′′-terpyridine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
29%		<strong>[1060805-69-7]4-bromo-2-acetylpyridine</strong> 3 (700 mg, 3.50 mmol, 2 eq) was added to a suspension of t-BuOK(590 mg, 5.25 mmol, 3 eq) in THF (25 mL). Pivalaldehyde (150 mg, 1.75 mmol, 1 eq) wasadded and the mixture was stirred at rt during 18 h. A solution of NH4OAc (1.50 g, 19.25mmol, 11 eq) in MeOH (10 mL) was introduced, and the mixture was heated at 70 C during5 h. After solvent evaporation, the crude product was purified by a short columnchromatography (Al2O3: Cyclohexane/Ethyl Acetate (96/4)) yielding dibromo-terpyridine 4 asa white solid (256 mg, 29%).

Reference： [1]Molecules,2018,vol. 23

81
[ 455-14-1 ]
[ 630-19-3 ]
[ 25617-34-9 ]

Reference： [1]ACS Catalysis,2016,vol. 6

82
[ 4318-37-0 ]
[ 630-19-3 ]
C₁₁H₂₂N₂O [ No CAS ]

Reference： [1]ACS Catalysis,2016,vol. 6

83
[ 64321-24-0 ]
[ 630-19-3 ]
2-(tert-butyl)-7-chloro-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
29%	With copper dichloride; In ethanol; at 75℃; for 12h;	Compound 14 (500mg, 2.90mmol), (CH3)3CHO (754mg, 8.80mmol) and CuCl2 (1.20g, 8.80mmol) were added into 5mL of ethanol. The obtained mixture was stirred at 75C for 12h. Then the mixture was filtrated and the filtrate was concentrated in vacuo and purified by column chromatography (CH2Cl2:CH3OH=20:1) to give compound 15 as white solid. Yield 29%; m.p. 121-123C. ESI-MS: 240.2 [M+H]+.

Reference： [1]Bioorganic and Medicinal Chemistry,2018,vol. 26,p. 3992 - 4000

84
[ 2469-99-0 ]
[ 630-19-3 ]
[ 1539-54-4 ]

Reference： [1]Organic and Biomolecular Chemistry,2018,vol. 16,p. 6391 - 6394

85
[ 1722-12-9 ]
[ 630-19-3 ]
[ 66522-06-3 ]

Reference： [1]Journal of Organic Chemistry,2019,vol. 84,p. 4363 - 4371

86
[ 39994-75-7 ]
[ 630-19-3 ]
(2R,4S,5S)-2-(tert-butyl)-4-methoxycarbonyl-5-methyl-1,3-oxazolidine [ No CAS ]
(2S,4S,5S)-2-(tert-butyl)-4-methoxycarbonyl-5-methyl-1,3-oxazolidine [ No CAS ]

Reference： [1]Journal of Organic Chemistry,2019,vol. 84,p. 10257 - 10279

87
[ 39994-75-7 ]
[ 630-19-3 ]
(2R,4S,5S)-2-(tert-butyl)-4-methoxycarbonyl-5-methyl-1,3-oxazolidine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With triethylamine; In Petroleum ether; at 110℃;Dean-Stark;	General procedure: The ester hydrochloride of the L-amino acid 1a-c (1.0 eq) was suspended in petroleum ether. Triethylamine (1.5 eq) and trimethylacetaldehyde (1.2 eq) were then added. The mixture was heated at reflux with continuous removal of water using a Dean- Stark apparatus for 18 h. The white precipitate was then filtered and washed with Et2O. The combined filtrates were concentrated under reduced pressure to furnish the oxazolidines or thiazolidine.

Reference： [1]Tetrahedron,2019,vol. 75

88
[ 4965-36-0 ]
[ 630-19-3 ]
7-bromo-2-(tert-butyl)quinoline [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
48%	With [4,4?-bis(1,1-dimethylethyl)-2,2?-bipyridine-N1,N1?]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate; toluene-4-sulfonic acid; lithium bromide; In dichloromethane; at 45℃; for 23h;Irradiation; Inert atmosphere;	General procedure: Step 1: Add quinoline compounds (see Table 1 for specific substances) and fatty aldehydes (see Table 1 for specific substances) to the reaction vessel.Lithium-containing catalysts (see Table 1 for specific substances),Additives (see Table 1 for specific substances),The organic acid (see Table 1 for specific substances) and the organic solvent (see Table 1 for specific substances) were added to the reaction vessel.Step 2: The reaction vessel is uniformly heated (e.g., heated in a water bath) to the temperature described in Table 1 and irradiated under blue light (which can be produced by BLUE LED), and the quinoline compound and the fatty aldehyde compound are reacted in a solvent, and The time described in Table 1 was continued; the reaction atmosphere to be described was selected to be nitrogen protected.Step 3: Purification step.Table 1: Examples 1-20 of quinoline compounds and fatty aldehydes, ruthenium catalysts, organic organic acids, additives, organic solvents (quinolines, fatty aldehydes, ruthenium catalysts, additives, and organic acids) Molar ratio, reaction temperature and reaction time.

Reference： [1]Green Chemistry,2019,vol. 21,p. 5512 - 5516
[2]Patent: CN110229102,2019,A .Location in patent: Paragraph 0045-0051; 0054

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P502	Refer to manufacturer/supplier for information on recovery/recycling

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
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Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 630-19-3 ] {[proInfo.proName]}

Quality Control of [ 630-19-3 ]

Related Doc. of [ 630-19-3 ]

Product Details of [ 630-19-3 ]

Calculated chemistry of [ 630-19-3 ]

Physicochemical Properties

Pharmacokinetics

Lipophilicity

Druglikeness

Water Solubility

Medicinal Chemistry

Safety of [ 630-19-3 ]

Application In Synthesis of [ 630-19-3 ]

[ 630-19-3 ] Synthesis Path-Upstream 1~22

[ 630-19-3 ] Synthesis Path-Downstream 1~88

Related Functional Groups of [ 630-19-3 ]

Aliphatic Chain Hydrocarbons

Aldehydes

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Related Functional Groups of
[ 630-19-3 ]