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Chemical Structure| 569-92-6 Chemical Structure| 569-92-6

Structure of Rhamnocitrin
CAS No.: 569-92-6

Chemical Structure| 569-92-6

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Rhamnocitrin can enhance cellular antioxidant defense capacity through regulation of HO-1 expression and MAPK signal transduction. It also exhibits prevention low-density lipoprotein from oxidation and atherogenesis. Rhamnocitrin can be purified from the rhizoma of alpinia officinarum hance,

Synonyms: C.I. 75650; Kaempferol 7-O-methyl ether; C.I. 75650, Kaempferol 7-O-methyl ether

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Product Citations

Product Citations

Zhao, Li ; Liao, Juan ; Zhao, Haijiao ; Feng, Cuiping ;

Abstract: This study systematically analyzed metabolite changes in quinoa after lactic acid bacteria (LAB) fermentation and the hypoglycemic mechanism of key metabolites inhibiting α-glucosidase. Mixed LAB fermentation significantly altered the metabolic profile of quinoa, and a total of 627 differential metabolites were identified, among which 471 were significantly up-regulated. After fermentation, the levels of flavonoids, phenolic acids, and amino acid derivatives increased significantly, and five new flavonoid metabolites were detected. The polyphenol extract from fermented quinoa (FQP) significantly inhibited α-glucosidase activity, with an IC₅₀ value of 0.17 mg/mL. Mechanistic studies indicated that FQP exerted mixed-type reversible inhibition, forming hydrogen bonds, van der Waals forces, and hydrophobic interactions with amino acid residues in the active center of α-glucosidase. These interactions induced conformational changes in the enzyme, thereby reducing its catalytic efficiency. This research provides a theoretical basis for the functional processing of quinoa and the development of novel hypoglycemic functional factors.

Keywords: Fermented quinoa ; Widely targeted metabolomics ; α-Glucosidase inhibition ; Hypoglycemic mechanisms ; Polyphenols

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Product Details of Rhamnocitrin

CAS No. :569-92-6
Formula : C16H12O6
M.W : 300.26
SMILES Code : COC1=CC(O)=C(C(C(O)=C2C3=CC=C(O)C=C3)=O)C(O2)=C1
Synonyms :
C.I. 75650; Kaempferol 7-O-methyl ether; C.I. 75650, Kaempferol 7-O-methyl ether
MDL No. :MFCD03419285
InChI Key :MQSZRBPYXNEFHF-UHFFFAOYSA-N
Pubchem ID :5320946

Safety of Rhamnocitrin

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.33mL

0.67mL

0.33mL

16.65mL

3.33mL

1.67mL

33.30mL

6.66mL

3.33mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

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