Home Cart 0 Sign in  

[ CAS No. 615-37-2 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 615-37-2
Chemical Structure| 615-37-2
Structure of 615-37-2 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Quality Control of [ 615-37-2 ]

Related Doc. of [ 615-37-2 ]

Alternatived Products of [ 615-37-2 ]
Product Citations

Product Details of [ 615-37-2 ]

CAS No. :615-37-2 MDL No. :MFCD00001042
Formula : C7H7I Boiling Point : -
Linear Structure Formula :- InChI Key :RINOYHWVBUKAQE-UHFFFAOYSA-N
M.W : 218.04 Pubchem ID :5128
Synonyms :

Calculated chemistry of [ 615-37-2 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 8
Num. arom. heavy atoms : 6
Fraction Csp3 : 0.14
Num. rotatable bonds : 0
Num. H-bond acceptors : 0.0
Num. H-bond donors : 0.0
Molar Refractivity : 44.12
TPSA : 0.0 Ų

Pharmacokinetics

GI absorption : Low
BBB permeant : Yes
P-gp substrate : No
CYP1A2 inhibitor : Yes
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -5.54 cm/s

Lipophilicity

Log Po/w (iLOGP) : 2.16
Log Po/w (XLOGP3) : 2.94
Log Po/w (WLOGP) : 2.6
Log Po/w (MLOGP) : 3.53
Log Po/w (SILICOS-IT) : 3.32
Consensus Log Po/w : 2.91

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 1.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -3.6
Solubility : 0.0549 mg/ml ; 0.000252 mol/l
Class : Soluble
Log S (Ali) : -2.6
Solubility : 0.545 mg/ml ; 0.0025 mol/l
Class : Soluble
Log S (SILICOS-IT) : -3.74
Solubility : 0.0396 mg/ml ; 0.000182 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 1.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 1.53

Safety of [ 615-37-2 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 615-37-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 615-37-2 ]
  • Downstream synthetic route of [ 615-37-2 ]

[ 615-37-2 ] Synthesis Path-Upstream   1~19

  • 1
  • [ 288-13-1 ]
  • [ 615-37-2 ]
  • [ 20157-44-2 ]
YieldReaction ConditionsOperation in experiment
94% at 82℃; for 70 h; 0535] Preparation of 1-(o-tolyl)-1H-pyrazole [0536] Operating protocol A (82 C., 70 hours) was followed using 117 mg of Chxn-Py-Al (0.4 mmoles), 383 ?l of 2-iodotoluene (3 mmoles), 136 mg of pyrazole (2 mmoles) and 1.2 ml of acetonitrile. [0537] The degree of transformation and selectivity for 1-(o-tolyl)-1H-pyrazole were 100percent. [0538] The residue obtained was purified by silica gel chromatography (eluent: hexane/dichloromethane, 100/0 to 0/100). [0539] 297 mg of a pale yellow oil was obtained, corresponding to a yield of 94percent by weight. [0540] The compound obtained had the following formula: [CHEMMOL-00045]
87% With 2,2'-biimidazole; copper(II) acetate monohydrate; caesium carbonate In dimethyl sulfoxide at 80℃; for 48 h; (1) The o-iodobenzene 0.218g (1.0mmol), pyrazole 0.069g (1.0mmol), Cu (OAc)2·H2O 0.030g (0.15mmol), 2,2- biimidazole 0.022g (0.15mmol), cesium carbonate 0.652g (2mmol), DMSO (2mL) was added the reaction tube with a piston, was heated to 80 deg.] C with stirring for 48 hours reaction.(2) TLC until the reaction was complete the reaction was followed ends.After the reaction was cooled to room temperature, diluted with water, extracted with ethyl acetate 3-4 was added, and the combined organic phases were dried over anhydrous sodium sulfate, filtered and concentrated to give the crude product.After the end of (3) to obtain the crude product was purified by column chromatography (petroleum ether / ethyl acetate elution) to give the desired product 4 (87percent yield).
83% With (N,N'-bis(salicylidenate)cyclohexane-1,2-diamine)copper(II); sodium hydroxide In dimethyl sulfoxide at 100℃; for 12 h; Sealed tube General procedure: Complex 2 (0.05 mmol) was added to a 5 mL of a sealed tube containing the aryl iodide or bromide (0.5 mmol), 1H-pyrazole (0.75 mmol), NaOH (1 mmol), and DMSO (1 mL). The mixture was stirred at 100 °C for 12 h. After being cooled to room temperature, the mixture was quenched with 10 mL H2O and extracted with EtOAc(3 × 20 mL). The combined EtOAc extracts were dried with anhydrous Na2SO4, filtered and the solvent was removed under reduced pressure.The residue was purified by flash column chromatography on silicagel with PE/EtOAc (from 10:1 to 5:1) as the eluent to afford the pure products. All N-aryl pyrazoles reported here are known products and were characterised by 1H NMR, and GC-MS.
65% With copper(l) iodide; tetrabutylammomium bromide; N-(2-aminoethyl)-N'-{2-[(2-aminoethyl)amino]ethyl}ethane-1,2-diamine In water at 125℃; for 12 h; General procedure: Iodobenzene (1.0 mmol), imidazole (1.5 mmol), TEPA (2.0 mmol), TBAB (0.3 mmol), CuI (0.1 mmol), and 3 mL H2O were added to a 10 mL flask, which was subsequently capped with a rubber balloon. The mixture was stirred in a preheated oil bath at 125 °C for 12 h. After cooling the mixture to the room temperature, 5 mL water was added and the product was extracted by ethyl acetate (10 mL×3). The combined organic layer was washed by brine (15 mL), dried over anhydrous MgSO4, and evaporated under the reduced pressure. Further purification by silica gel column chromatography (6:1 petroleum ether/ethyl acetate) give the 1-phenyl-1H-imidazole.
40% With copper diacetate; sodium hydroxide; 3-(diphenylphosphino)propionic acid In 1,4-dioxane at 100℃; for 24 h; Sealed tube General procedure: Cu(OAc)2 (0.03mmol), L2 (0.06mmol), aryl idione or bromide (0.5mmol), 1H-pyrazole (0.75mmol), NaOH (1mmol), and 1,4-dioxane (1mL) was added into a 5mL tube, then sealed. The mixture was stirred at 100°C for certain time. After cooling to room temperature, the mixture was quenched with 10mL H2O and extracted with EtOAc (3×20mL). The combined EtOAc extracts were dried with anhydrous Na2SO4 and filtrated and the solvent was removed under reduced pressure. The residue was purified by flash column chromatography on silica gel with PE/EtOAc, as the eluent, to afford the desired products.

Reference: [1] European Journal of Organic Chemistry, 2004, # 4, p. 695 - 709
[2] Patent: US2003/236413, 2003, A1, . Location in patent: Page 21
[3] Patent: CN104447557, 2017, B, . Location in patent: Paragraph 0050; 0051; 0052; 0053; 0054; 0055
[4] Journal of Chemical Research, 2013, vol. 37, # 10, p. 636 - 637
[5] Synlett, 2006, # 13, p. 2124 - 2126
[6] Tetrahedron Letters, 2009, vol. 50, # 42, p. 5868 - 5871
[7] Tetrahedron, 2013, vol. 69, # 30, p. 6230 - 6233
[8] Chinese Chemical Letters, 2014, vol. 25, # 5, p. 775 - 778
[9] Synlett, 2012, vol. 23, # 19, p. 2763 - 2767
  • 2
  • [ 615-37-2 ]
  • [ 95-52-3 ]
Reference: [1] Journal of the American Chemical Society, 2012, vol. 134, # 26, p. 10795 - 10798
  • 3
  • [ 615-37-2 ]
  • [ 4387-36-4 ]
Reference: [1] Patent: US4124631, 1978, A,
  • 4
  • [ 615-37-2 ]
  • [ 26260-02-6 ]
Reference: [1] Helvetica Chimica Acta, 1925, vol. 8, p. 441
[2] Journal of the Chemical Society, 1958, p. 1375,1378
  • 5
  • [ 615-37-2 ]
  • [ 7745-92-8 ]
  • [ 5326-38-5 ]
  • [ 6277-17-4 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1988, p. 1281 - 1286
  • 6
  • [ 615-37-2 ]
  • [ 609-67-6 ]
Reference: [1] Patent: CN107987057, 2018, A,
  • 7
  • [ 615-37-2 ]
  • [ 5159-41-1 ]
Reference: [1] Journal of the Chemical Society, 1958, p. 1375,1378
  • 8
  • [ 615-37-2 ]
  • [ 40400-13-3 ]
YieldReaction ConditionsOperation in experiment
69% With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) In tetrachloromethaneReflux A mixture of l-iodo-2-methylbenzene (0.5 g, 2.3 mmol), N-bromosuccinimide (0.7 g, 3.7 mmol) and 2,2'-azobisisobutyronitrile (0.02 g, 0.1 mmol) in tetrachloromethane (10 mL) was heated at reflux until the reaction was completed (tic control). After cooled down to the ambient temperature the reaction mixture was quenched with water and water layer was extracted with dichloromethane. Combined organic phases were washed with sodium hydrocarbonate, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by column chromatography (silica gel; hexane/ethyl acetate 9: 1) to give l-(bromomethyl)-2-iodobenzene (0.5 g) as yellowish oil; yield 69percent.
Reference: [1] Patent: WO2017/68064, 2017, A1, . Location in patent: Page/Page column 188; 189
[2] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985, p. 1583 - 1588
[3] Journal of the Chemical Society, 1941, p. 487,489
[4] American Chemical Journal, 1882, vol. 4, p. 101
[5] Journal of the Chemical Society, 1958, p. 1375,1378
[6] Canadian Journal of Chemistry, 1988, vol. 66, p. 2256 - 2258
[7] Advanced Synthesis and Catalysis, 2004, vol. 346, # 7, p. 767 - 776
[8] Angewandte Chemie - International Edition, 2012, vol. 51, # 16, p. 3826 - 3831
  • 9
  • [ 128-08-5 ]
  • [ 615-37-2 ]
  • [ 40400-13-3 ]
Reference: [1] Patent: US5180741, 1993, A,
  • 10
  • [ 615-37-2 ]
  • [ 40400-15-5 ]
Reference: [1] Journal of the Chemical Society, 1941, p. 487,489
  • 11
  • [ 615-37-2 ]
  • [ 116632-39-4 ]
Reference: [1] Recueil des Travaux Chimiques des Pays-Bas, 1912, vol. 31, p. 271
  • 12
  • [ 615-37-2 ]
  • [ 7745-92-8 ]
  • [ 5326-38-5 ]
  • [ 6277-17-4 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1988, p. 1281 - 1286
  • 13
  • [ 615-37-2 ]
  • [ 5326-38-5 ]
Reference: [1] Chemische Berichte, 1897, vol. 30, p. 3000
[2] Justus Liebigs Annalen der Chemie, 1871, vol. 158, p. 347
[3] Chemische Berichte, 1897, vol. 30, p. 3000
[4] Journal of the Chemical Society, 1929, p. 2742
[5] Journal of the American Chemical Society, 1919, vol. 41, p. 2041
  • 14
  • [ 615-37-2 ]
  • [ 7664-93-9 ]
  • [ 5326-38-5 ]
Reference: [1] Journal of the Chemical Society, 1929, p. 2742
[2] Journal of the American Chemical Society, 1919, vol. 41, p. 2041
  • 15
  • [ 615-37-2 ]
  • [ 90794-29-9 ]
Reference: [1] Journal of the Chemical Society, 1941, p. 487,489
  • 16
  • [ 615-37-2 ]
  • [ 39959-51-8 ]
Reference: [1] American Chemical Journal, 1882, vol. 4, p. 101
  • 17
  • [ 615-37-2 ]
  • [ 62-53-3 ]
  • [ 1205-39-6 ]
YieldReaction ConditionsOperation in experiment
70% With potassium hydroxide In dimethyl sulfoxide at 120℃; for 16 h; Inert atmosphere To a mixture of 0.05 g catalyst and aryl iodide (1.0 mmol) in9.0 cm3 DMSO, amine (1.2 mmol) and KOH (1.5 mmol)was added and the mixture was vigorously stirred at 120 Cfor appropriate time under a dry nitrogen atmosphere. Afterthe completion of the reaction, the catalyst was filtered offand washed with water followed by acetone and dried inoven. The filtrate was extracted with ethyl acetate(3 9 20 cm3) and the combined organic layers were driedwith anhydrous Na2SO4 by vacuum. The filtrate was concentratedby vacuum and the resulting residue was purifiedby column chromatography on silica gel to provide thedesired product. All the products are known and the spectroscopicdata (FT-IR and NMR) and melting points wereconsistent with those reported in the literature [26].
63% With potassium hydroxide In dimethyl sulfoxide at 140℃; for 22 h; Inert atmosphere General procedure: In an oven dried 100 mL RB flask, polymer supported Cu(II)catalyst (50 mg, 0.0098 mmol), aryl halide (1 mmol), aromatic amines (1.2 mmol), KOH (1 mmol), and 10 ml DMSO were stirred under nitrogen atmosphere, at 140 °C. The reaction mixtures were collected at different time intervals and identified by GCMS and quantified by GC. After the completion of the reaction, the catalyst was filtered off and washed with water followed by acetone and dried in oven. The filtrate was extracted with ethyl acetate(3 x 20 mL) and the combined organic layers were dried with anhydrous Na2SO4 by vacuum. The filtrate was concentrated by vacuum and the resulting residue was purified by column chromatography on silica gel to provide the desired product.
62% With potassium hydroxide In dimethyl sulfoxide at 140℃; for 16 h; Inert atmosphere General procedure: In an oven dried 100 mL round bottom flask, Cu-grafted cat-alyst (0.05 g), aryl halide (1 mmol), aromatic amines (1.2 mmol),KOH (1 mmol), and 10 mL DMSO were stirred under nitrogen atmo-sphere, at 140C. The reaction mixtures were collected at differenttime intervals and identified by GC–MS and quantified by GC.After the completion of the reaction, the catalyst was filtered offand washed with water followed by acetone and dried in oven.The filtrate was extracted with ethyl acetate (3 × 20 mL) and thecombined organic layers were dried with anhydrous Na2SO4byvacuum. The filtrate was concentrated by vacuum and the result-ing residue was purified by column chromatography on silica gelto provide the desired product.
62% With C104H96N16O8Pd2(4+)*4NO3(1-); sodium t-butanolate In toluene at 110℃; for 18 h; General procedure: In a 50 mL round bottom flask, the mixture of iodobenzene (2 mmol), amine (2.4 mmol), t-BuONa (3 mmol), and 1 as catalyst (0.05 mol percent) was taken in toluene (10 mL). The reaction mixture was then heated to 110°C and continued for 12–18 h. The progress of the reaction was monitored by TLC. Upon completion of the reaction the aqueous reaction mixture was extracted with ethyl acetate, washed with brine, dried over MgSO4, concentrated, and purified by column chromatography on silica gel which afforded corresponding coupling products (yield 75–96percent).

Reference: [1] Organometallics, 2012, vol. 31, # 21, p. 7336 - 7338
[2] Applied Organometallic Chemistry, 2014, vol. 28, # 2, p. 81 - 85
[3] Monatshefte fuer Chemie, 2015, vol. 146, # 8, p. 1329 - 1334
[4] Journal of Organometallic Chemistry, 2012, vol. 696, # 26, p. 4264 - 4274
[5] Journal of Molecular Catalysis A: Chemical, 2014, vol. 387, p. 7 - 19
[6] Tetrahedron Letters, 2016, vol. 57, # 14, p. 1532 - 1536
[7] Asian Journal of Chemistry, 2015, vol. 27, # 3, p. 1075 - 1078
[8] Angewandte Chemie - International Edition, 2016, vol. 55, # 42, p. 13219 - 13223[9] Angew. Chem., 2016, vol. 128, # 42, p. 13413 - 13417,5
[10] ACS Catalysis, 2014, vol. 4, # 6, p. 1725 - 1734
  • 18
  • [ 615-37-2 ]
  • [ 7745-92-8 ]
  • [ 5326-38-5 ]
  • [ 6277-17-4 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1988, p. 1281 - 1286
  • 19
  • [ 615-37-2 ]
  • [ 115290-81-8 ]
  • [ 82248-59-7 ]
YieldReaction ConditionsOperation in experiment
99%
Stage #1: With potassium carbonate In toluene at 148℃; for 21 h; Heating / reflux
Stage #2: With hydrogenchloride In water
Stage #3: With sodium hydroxide In water
(R)-N-methyl-3-(2-methylphenoxy)-benzenepropanamine hydrochloride:; A 3 -necked 100 ml glass reactor was flushed for 15 min with N2 and subsequently charged with 15 g (90.8 mmol) of the above mentioned (3R)-methyl-3-hydroxy-3- phenylpropylamine (>99 percent ee, chiral HPLC), potassium phosphate (28.9 g, 136.2 mmol) and 1.73 g copper(I)iodide (9.8 mmol, 10 mol-percent). 60 ml of toluene was added to the mixture and the suspension was stirred for 5 min. 12.8 ml (100 mmol) of 2-iodotoluene was added and the reaction mixture was heated to reflux for 24 h. After cooling to room temperature, the suspension was filtered and the filter cake was washed with 60 ml of toluene. 75 ml of water was added to the filtrate and the mixture was stirred for 10 min at room temperature. The aqueous phase was brought to pH 1-2 with 30 percent HCl and the phases were separated. 60 ml of toluene was added to the aqueous phase and aqueous NaOH was added until pH 12-14 of the aqueous phase was reached. After stirring for EPO <DP n="16"/>10 min the phases were separated. The organic phase was evaporated under reduced pressure yielding 25 g of an oil.The oil was redissolved in 80 ml of toluene, warmed to 80 °C and 36 g of a 10 percent HCl- ethyl acetate solution was added dropwise to the solution. During cooling of the solution a white solid precipitated. After 5 h at room temperature, the suspension was filtered and the residue was dried in vacuum at about 50 °C to yield 22 g (75.4 mmol, 83 percent) of (R)- N-methyl-3-(2-methylphenoxy)-benzenepropanamine hydrochloride.The (R)-N-methyl-3-(2-methylphenoxy)-benzenepropanamine hydrochloride salt was placed in a 100 ml reaction vessel and 55 ml of isopropanol was added. Upon heating to reflux temperature all solids were dissolved. Slow cooling to room temperature gave 18.1 g (82 percent) of colorless (R)-N-methyl-3-(2-methylphenoxy)-benzenepropanamine hydrochloride (>99 percent ee, HPLC).
94%
Stage #1: With potassium carbonate In toluene at 148℃; for 21 h; Heating / reflux
Stage #2: With hydrogenchloride In water
Stage #3: With sodium hydroxide In water
(R)-N-methyl-3-(2-methylphenoxy)-benzenepropanamine hydrochloride:; A 3 -necked 100 ml glass reactor was flushed for 15 min with N2 and subsequently charged with 15 g (90.8 mmol) of the above mentioned (3R)-methyl-3-hydroxy-3- phenylpropylamine (>99 percent ee, chiral HPLC), potassium phosphate (28.9 g, 136.2 mmol) and 1.73 g copper(I)iodide (9.8 mmol, 10 mol-percent). 60 ml of toluene was added to the mixture and the suspension was stirred for 5 min. 12.8 ml (100 mmol) of 2-iodotoluene was added and the reaction mixture was heated to reflux for 24 h. After cooling to room temperature, the suspension was filtered and the filter cake was washed with 60 ml of toluene. 75 ml of water was added to the filtrate and the mixture was stirred for 10 min at room temperature. The aqueous phase was brought to pH 1-2 with 30 percent HCl and the phases were separated. 60 ml of toluene was added to the aqueous phase and aqueous NaOH was added until pH 12-14 of the aqueous phase was reached. After stirring for EPO <DP n="16"/>10 min the phases were separated. The organic phase was evaporated under reduced pressure yielding 25 g of an oil.The oil was redissolved in 80 ml of toluene, warmed to 80 °C and 36 g of a 10 percent HCl- ethyl acetate solution was added dropwise to the solution. During cooling of the solution a white solid precipitated. After 5 h at room temperature, the suspension was filtered and the residue was dried in vacuum at about 50 °C to yield 22 g (75.4 mmol, 83 percent) of (R)- N-methyl-3-(2-methylphenoxy)-benzenepropanamine hydrochloride.The (R)-N-methyl-3-(2-methylphenoxy)-benzenepropanamine hydrochloride salt was placed in a 100 ml reaction vessel and 55 ml of isopropanol was added. Upon heating to reflux temperature all solids were dissolved. Slow cooling to room temperature gave 18.1 g (82 percent) of colorless (R)-N-methyl-3-(2-methylphenoxy)-benzenepropanamine hydrochloride (>99 percent ee, HPLC).
82%
Stage #1: With potassium phosphate In toluene for 24 h; Heating / reflux
Stage #2: With hydrogenchloride In water
Stage #3: With sodium hydroxide In water
(R)-N-methyl-3-(2-methylphenoxy)-benzenepropanamine hydrochloride:; A 3 -necked 100 ml glass reactor was flushed for 15 min with N2 and subsequently charged with 15 g (90.8 mmol) of the above mentioned (3R)-methyl-3-hydroxy-3- phenylpropylamine (>99 percent ee, chiral HPLC), potassium phosphate (28.9 g, 136.2 mmol) and 1.73 g copper(I)iodide (9.8 mmol, 10 mol-percent). 60 ml of toluene was added to the mixture and the suspension was stirred for 5 min. 12.8 ml (100 mmol) of 2-iodotoluene was added and the reaction mixture was heated to reflux for 24 h. After cooling to room temperature, the suspension was filtered and the filter cake was washed with 60 ml of toluene. 75 ml of water was added to the filtrate and the mixture was stirred for 10 min at room temperature. The aqueous phase was brought to pH 1-2 with 30 percent HCl and the phases were separated. 60 ml of toluene was added to the aqueous phase and aqueous NaOH was added until pH 12-14 of the aqueous phase was reached. After stirring for EPO <DP n="16"/>10 min the phases were separated. The organic phase was evaporated under reduced pressure yielding 25 g of an oil.The oil was redissolved in 80 ml of toluene, warmed to 80 °C and 36 g of a 10 percent HCl- ethyl acetate solution was added dropwise to the solution. During cooling of the solution a white solid precipitated. After 5 h at room temperature, the suspension was filtered and the residue was dried in vacuum at about 50 °C to yield 22 g (75.4 mmol, 83 percent) of (R)- N-methyl-3-(2-methylphenoxy)-benzenepropanamine hydrochloride.The (R)-N-methyl-3-(2-methylphenoxy)-benzenepropanamine hydrochloride salt was placed in a 100 ml reaction vessel and 55 ml of isopropanol was added. Upon heating to reflux temperature all solids were dissolved. Slow cooling to room temperature gave 18.1 g (82 percent) of colorless (R)-N-methyl-3-(2-methylphenoxy)-benzenepropanamine hydrochloride (>99 percent ee, HPLC).
Reference: [1] Patent: WO2007/10082, 2007, A1, . Location in patent: Page/Page column 18-19
[2] Patent: WO2007/10082, 2007, A1, . Location in patent: Page/Page column 18-19
[3] Patent: WO2007/10082, 2007, A1, . Location in patent: Page/Page column 14-15
[4] Patent: US2007/10678, 2007, A1, . Location in patent: Page/Page column 7
[5] Patent: US2007/10678, 2007, A1, . Location in patent: Page/Page column 7
[6] Patent: WO2007/6132, 2007, A1, . Location in patent: Page/Page column 20
[7] Patent: WO2007/6132, 2007, A1, . Location in patent: Page/Page column 21
Recommend Products
Same Skeleton Products
Historical Records