Purity | Size | Price | VIP Price | USA Stock *0-1 Day | Global Stock *5-7 Days | Quantity | ||||||
{[ item.p_purity ]} | {[ item.pr_size ]} | Inquiry |
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price) ]} |
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]} | Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate,item.pr_is_large_size_no_price) ]} | {[ item.pr_usastock ]} | in stock Inquiry - | {[ item.pr_chinastock ]} | {[ item.pr_remark ]} in stock Inquiry - | Login | Inquiry |
Please Login or Create an Account to: See VIP prices and availability
CAS No. : | 619-66-9 | MDL No. : | MFCD00006951 |
Formula : | C8H6O3 | Boiling Point : | No data available |
Linear Structure Formula : | - | InChI Key : | GOUHYARYYWKXHS-UHFFFAOYSA-N |
M.W : | 150.13 | Pubchem ID : | 12088 |
Synonyms : |
|
Signal Word: | Warning | Class: | |
Precautionary Statements: | P261-P305+P351+P338 | UN#: | |
Hazard Statements: | H315-H319-H335 | Packing Group: | |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Example 278 4-[(2-Methoxy-5-phenylcarbamoyl-phenylamino)-methyl]-benzoic acid The title compound has been made using the procedure of Example 50, but using <strong>[120-35-4]3-amino-4-methoxy-benzanilide</strong> and 4carboxybenzaldehyde, which are available from Aldrich, as starting materials; mp >240 C. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
93.3% | With triethylamine; In ethanol; at 60℃; for 4h;Product distribution / selectivity; | To a solution of 4-formylbenzoic acid (250 mg, 1.67 mmol) in ethanol (5 mL) were added triethylamine (0.28 mL, 2.00 mmol) and <strong>[57497-39-9]N-tert-butylhydroxylamine hydrochloride</strong> (251 mg, 2.00 mmol). The mixture was then heated at 60° C. for 4 hours. The solvent was evaporated in vacuo and the residue purified by flash column chromatography on silica gel using 1percent acetic acid in ethyl acetate. The product was obtained as a white solid (320 mg, 1.56 mmol, 93.3percent). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
In ethanol; at 60℃; for 0.5h; | General procedure: A mixture of corresponding hydrazinylpyridazine 1 or 5 (1 mmol) and aldehyde 2 (1.1 mmol) in ethanol (5 mL) was heated at 60 oC for 0.5 h. The formation of hydrazone was checked by TLC and the reaction mixture was cooled to rt. Oxone (1.5 mmol) was added to the mixture at rt followed by tetramethyl ammonium bromide (0.2 mmol) and the resulting mixture was heated at 60 oC for another 5 h. The mixture was cooled to rt and extracted with dichloromethane (2 × 25 mL), dried over anhydrous sodium sulphate and concentrated to obtain a residue which was purified by column chromatography using hexane/ethyl acetate as eluent to furnish the desired triazolopyridazines 4 and 7. | |
In ethanol; at 60℃; for 0.5h; | General procedure: A mixture of corresponding hydrazinylpyridazine 1 or 5 (1 mmol) and aldehyde 2 (1.1 mmol) in ethanol (5 mL) was heated at 60 C for 0.5 h. The formation of hydrazone was checked by TLC and the reaction mixture was cooled to rt. Oxone (1.5 mmol) was added to the mixture at rt followed by tetramethyl ammonium bromide (0.2 mmol) and the resulting mixture was heated at 60 C for another 5 h. The mixture was cooled to rt and extracted with dichloromethane (2 × 25 mL), dried over anhydrous sodium sulfate and concentrated to obtain a residue which was purified by column chromatography using hexane/ethyl acetate as eluent to furnish the desired triazolopyridazines 4 and 7 (See reference no; 7 for supporting information). |
[ 99-04-7 ]
3-Methylbenzoic acid(Flakes or Chunks or Granular)
Similarity: 1.00
[ 99-04-7 ]
3-Methylbenzoic acid(Flakes or Chunks or Granular)
Similarity: 1.00