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Chemical Structure| 111061-55-3 Chemical Structure| 111061-55-3
Chemical Structure| 111061-55-3

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Product Details of Fmoc-Hse(Trt)-OH

CAS No. :111061-55-3
Formula : C38H33NO5
M.W : 583.67
SMILES Code : O=C(O)[C@H](CCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)NC(OCC4C5=CC=CC=C5C6=CC=CC=C46)=O
MDL No. :MFCD00270544
InChI Key :QUTREFXHXPNEJN-DHUJRADRSA-N
Pubchem ID :11387678

Safety of Fmoc-Hse(Trt)-OH

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of Fmoc-Hse(Trt)-OH

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 111061-55-3 ]

[ 111061-55-3 ] Synthesis Path-Downstream   1~25

  • 1
  • [ 28920-43-6 ]
  • [ 111061-53-1 ]
  • [ 111061-55-3 ]
  • 2
  • [ 6066-82-6 ]
  • [ 111061-55-3 ]
  • [1-(2,5-dioxo-pyrrolidine-1-carbonyl)-3-trityloxy-propyl]-carbamic acid 9<i>H</i>-fluoren-9-ylmethyl ester [ No CAS ]
  • 3
  • [ 29022-11-5 ]
  • [ 71989-18-9 ]
  • [ 71989-26-9 ]
  • [ 111061-55-3 ]
  • 2-fluoro-5-nitrobenzoyl chloridebiotin-N-hydroxysuccinimide [ No CAS ]
  • D3-Biotin [ No CAS ]
  • 4
  • [ 29022-11-5 ]
  • [ 71989-18-9 ]
  • [ 71989-26-9 ]
  • [ 111061-55-3 ]
  • 2-fluoro-5-nitrobenzoyl chloride [ No CAS ]
  • D3 [ No CAS ]
  • 5
  • [ 111061-55-3 ]
  • (H-Gly-ol)-Trt(2-Cl)-resin [ No CAS ]
  • 2-amino-4-hydroxy-<i>N</i>-(2-hydroxy-ethyl)-butyramide [ No CAS ]
  • 6
  • [ 159751-47-0 ]
  • [ 111061-55-3 ]
  • [ 76-05-1 ]
  • [ 344-25-2 ]
  • Fmoc-His-OAll [ No CAS ]
  • Fmoc-Orn(Dde)-OHacetyl methylthiourea hydroiodide [ No CAS ]
  • 4-[5-[3-(<i>N</i>'-acetyl-guanidino)-propyl]-14-(2-hydroxy-ethyl)-11-(1<i>H</i>-imidazol-4-ylmethyl)-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-8-yl]-butyric acid; compound with trifluoro-acetic acid [ No CAS ]
  • 7
  • [ 111061-55-3 ]
  • Fmoc-Hse-Gly-OH [ No CAS ]
  • 8
  • [ 111061-55-3 ]
  • Fmoc-Hse(Tr)-Gly-OH [ No CAS ]
  • 9
  • [ 111061-55-3 ]
  • [ 261636-32-2 ]
  • 10
  • C22H21N2OPolS [ No CAS ]
  • [ 111061-55-3 ]
  • C60H52N3O5PolS [ No CAS ]
  • 11
  • C17H25Cl2N2O5Pol [ No CAS ]
  • [ 111061-55-3 ]
  • C55H56Cl2N3O9Pol [ No CAS ]
  • 12
  • [ 1218817-73-2 ]
  • [ 111061-55-3 ]
  • [ 1218817-77-6 ]
YieldReaction ConditionsOperation in experiment
81% With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20℃; for 3h; To a stirred solution of (4-(5-heptyl-1,2,4-oxadiazol-3- yl)phenyl)methanamine (LX, prepared with procedures similar to that described in Example 79) (0.290 g, 1.20 mmol) and (S)-2-(((9No.-fluoren-9-yl)methoxy)carbonylamino)-4- (trityloxy)butanoic acid (0.841 g, 1.44 mmol) in dichloromethane (6 mL) was added N-(3- dimethylaminopropyl)--V-ethylcarbodiimide hydrochloride (0.282 g, 1.44 mmol). The reaction mixture was allowed to stir at room temperature. After 3 hours, the reaction mixture was diluted with dichloromethane and washed with IN hydrochloric acid. The organic phase was dried (sodium sulfate), filtered, and concentrated to provide a yellow oil. Flash chromatography using an Isco Combiflash unit (40 g Sitheta2 column, 30-50% ethyl acetate/hexanes) afforded 0.807 g (81%) of(5)-(9H-fluoren-9-yl)methyl l-(4-(5-heptyl-1,2,4-oxadiazol-3-yl)benzylamino)-1-oxo- 4-(trityloxy)butan-2-ylcarbamate (LXI) as a yellow solid: 1H NMR (CDCl3) delta 8.00-7.95 (m, 2H), 7.76-7.70 (m, 2H), 7.53-7.47 (m, 2H), 7.42-7.33 (m, 8H), 7.30-7.17 (m, 13H), 6.56 (br s, 1H), 6.04 (d, J= 6 Hz, 1H), 4.45-4.28 (m, 5H), 4.19-4.12 (m, 1H), 3.40-3.24 (m, 2H), 2.93 (t, J= 7.6 Hz, 2H), 2.19-2.01 (m, 2H), 1.92-1.81 (m, 2H), 1.48-1.23 (m, 8H), 0.89 (t, J= 6.9 Hz, 3H) ppm.
  • 13
  • [ 29022-11-5 ]
  • [ 35661-39-3 ]
  • [ 111061-55-3 ]
  • Fmoc-pentamethylchroman(PMC)-Arg-Wang resin [ No CAS ]
  • [ 1354954-71-4 ]
  • 14
  • Fmoc-Rink resin [ No CAS ]
  • [ 7304-32-7 ]
  • [ 71989-18-9 ]
  • [ 71989-26-9 ]
  • [ 84358-13-4 ]
  • [ 111061-55-3 ]
  • [ 1192373-75-3 ]
  • 15
  • hydroxymethylbenzamide [ No CAS ]
  • [ 111061-55-3 ]
  • C31H29N2O4Pol [ No CAS ]
  • 16
  • [ 68858-20-8 ]
  • [ 71989-31-6 ]
  • [ 71989-33-8 ]
  • [ 111061-55-3 ]
  • C36H43N4O7Pol [ No CAS ]
  • 17
  • [ 35661-39-3 ]
  • [ 71989-31-6 ]
  • [ 71989-33-8 ]
  • [ 71989-35-0 ]
  • [ 111061-55-3 ]
  • [ 143824-78-6 ]
  • PSPWAT(Hse)-NH2 [ No CAS ]
  • 18
  • (S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetic acid [ No CAS ]
  • [ 101555-63-9 ]
  • [ 111061-55-3 ]
  • (S)-N-((S)-1-amino-4-hydroxy-1-oxobutan-2-yl)-1-((S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl)piperidine-2-carboxamide [ No CAS ]
  • 19
  • [ 111061-55-3 ]
  • C28H28N2O6 [ No CAS ]
  • 20
  • [ 111061-55-3 ]
  • C28H26N2O7 [ No CAS ]
  • C28H26N2O6 [ No CAS ]
  • C28H26N2O6 [ No CAS ]
  • 21
  • [ 111061-55-3 ]
  • C28H26N2O6 [ No CAS ]
  • C28H26N2O6 [ No CAS ]
  • 22
  • [ 2462-31-9 ]
  • [ 111061-55-3 ]
  • C47H42N2O6 [ No CAS ]
  • 23
  • [ 3235-69-6 ]
  • [ 159610-93-2 ]
  • C26H19N2O5Pol [ No CAS ]
  • [ 132684-59-4 ]
  • [ 111061-55-3 ]
  • Mor-Hfe-Ser(Me)-Hse-ACC [ No CAS ]
  • 24
  • [ 3235-69-6 ]
  • [ 35661-60-0 ]
  • C26H19N2O5Pol [ No CAS ]
  • [ 132684-59-4 ]
  • [ 111061-55-3 ]
  • Mor-Hfe-Hse-Leu-ACC [ No CAS ]
  • 25
  • [ 3235-69-6 ]
  • [ 159610-93-2 ]
  • [ 35661-60-0 ]
  • C26H19N2O5Pol [ No CAS ]
  • [ 111061-55-3 ]
  • Mor-Hse-Ser(Me)-Leu-ACC [ No CAS ]
 

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