Home Cart 0 Sign in  
X

[ CAS No. 123-32-0 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
3d Animation Molecule Structure of 123-32-0
Chemical Structure| 123-32-0
Chemical Structure| 123-32-0
Structure of 123-32-0 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 123-32-0 ]

Related Doc. of [ 123-32-0 ]

Alternatived Products of [ 123-32-0 ]
Product Citations

Product Details of [ 123-32-0 ]

CAS No. :123-32-0 MDL No. :MFCD00006147
Formula : C6H8N2 Boiling Point : -
Linear Structure Formula :C4N2H2(CH3)2 InChI Key :LCZUOKDVTBMCMX-UHFFFAOYSA-N
M.W : 108.14 Pubchem ID :31252
Synonyms :
NSC 49139

Calculated chemistry of [ 123-32-0 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 8
Num. arom. heavy atoms : 6
Fraction Csp3 : 0.33
Num. rotatable bonds : 0
Num. H-bond acceptors : 2.0
Num. H-bond donors : 0.0
Molar Refractivity : 31.96
TPSA : 25.78 Ų

Pharmacokinetics

GI absorption : High
BBB permeant : Yes
P-gp substrate : No
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -6.51 cm/s

Lipophilicity

Log Po/w (iLOGP) : 1.57
Log Po/w (XLOGP3) : 0.63
Log Po/w (WLOGP) : 1.09
Log Po/w (MLOGP) : -0.14
Log Po/w (SILICOS-IT) : 1.81
Consensus Log Po/w : 0.99

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 1.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -1.46
Solubility : 3.73 mg/ml ; 0.0345 mol/l
Class : Very soluble
Log S (Ali) : -0.75
Solubility : 19.4 mg/ml ; 0.179 mol/l
Class : Very soluble
Log S (SILICOS-IT) : -2.36
Solubility : 0.471 mg/ml ; 0.00436 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 0.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 1.57

Safety of [ 123-32-0 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 123-32-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 123-32-0 ]
  • Downstream synthetic route of [ 123-32-0 ]

[ 123-32-0 ] Synthesis Path-Upstream   1~70

  • 1
  • [ 57-55-6 ]
  • [ 123-32-0 ]
  • [ 6168-72-5 ]
  • [ 14008-30-1 ]
  • [ 78-90-0 ]
  • [ 108-49-6 ]
Reference: [1] Patent: CN104693038, 2017, B, . Location in patent: Paragraph 0052-0053; 0089
[2] Patent: CN104693038, 2017, B, . Location in patent: Paragraph 0056-0057; 0089
[3] Patent: CN104693038, 2017, B, . Location in patent: Paragraph 0058-0059; 0089
[4] Patent: CN104693038, 2017, B, . Location in patent: Paragraph 0060-0061; 0089
[5] Patent: CN104693038, 2017, B, . Location in patent: Paragraph 0076-0077; 0089
  • 2
  • [ 123-32-0 ]
  • [ 2815-34-1 ]
Reference: [1] Bulletin de la Societe Chimique de France, 1932, vol. <4> 51, p. 360,368, 371
[2] Patent: US2843589, 1955, ,
[3] Patent: US2843589, 1955, ,
[4] Patent: US2843589, 1955, ,
[5] Angewandte Chemie - International Edition, 2017, vol. 56, # 36, p. 10886 - 10889[6] Angew. Chem., 2017, vol. 129, p. 11026 - 11029,4
  • 3
  • [ 123-32-0 ]
  • [ 2815-34-1 ]
  • [ 6284-84-0 ]
Reference: [1] Patent: US2843589, 1955, ,
[2] Journal of Organic Chemistry, 1987, vol. 52, # 6, p. 1043 - 1046
[3] Patent: US2843589, 1955, ,
  • 4
  • [ 123-32-0 ]
  • [ 2815-34-1 ]
  • [ 59573-44-3 ]
Reference: [1] Angewandte Chemie - International Edition, 2017, vol. 56, # 36, p. 10886 - 10889[2] Angew. Chem., 2017, vol. 129, p. 11026 - 11029,4
  • 5
  • [ 930-61-0 ]
  • [ 67-66-3 ]
  • [ 14331-54-5 ]
  • [ 123-32-0 ]
  • [ 54198-89-9 ]
  • [ 4472-45-1 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980, p. 1431 - 1435
  • 6
  • [ 930-61-0 ]
  • [ 67-66-3 ]
  • [ 14331-54-5 ]
  • [ 123-32-0 ]
  • [ 95-89-6 ]
  • [ 38557-72-1 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980, p. 1431 - 1435
  • 7
  • [ 930-61-0 ]
  • [ 67-66-3 ]
  • [ 14331-54-5 ]
  • [ 123-32-0 ]
  • [ 4472-45-1 ]
  • [ 108-50-9 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980, p. 1431 - 1435
  • 8
  • [ 123-32-0 ]
  • [ 22868-76-4 ]
  • [ 1558-17-4 ]
YieldReaction ConditionsOperation in experiment
72% for 0.0833333 h; Irradiation General procedure: Irradiation procedure. The dimethylpyrazine or dimethylpyrimidine was placed in a Pyrex tube, attached to the vacuum line, and subjected to three freeze-thaw cycles. The remaining material was then allowed to vaporize into a quartz reaction flask (3 L) that had been evacuated overnight. The resulting pressure in the reaction flask ranged from 1.0 to 1.5 Torr. The flask was irradiated for 5 min. in a Rayonet reaction equipped with either 2, 4,6, 8, or 10 low-pressure 2537 Å Hg lamps.
Reference: [1] Arkivoc, 2017, vol. 2017, # 5, p. 216 - 228
  • 9
  • [ 22868-76-4 ]
  • [ 123-32-0 ]
  • [ 1558-17-4 ]
YieldReaction ConditionsOperation in experiment
62% for 0.0833333 h; Irradiation General procedure: Irradiation procedure. The dimethylpyrazine or dimethylpyrimidine was placed in a Pyrex tube, attached to the vacuum line, and subjected to three freeze-thaw cycles. The remaining material was then allowed to vaporize into a quartz reaction flask (3 L) that had been evacuated overnight. The resulting pressure in the reaction flask ranged from 1.0 to 1.5 Torr. The flask was irradiated for 5 min. in a Rayonet reaction equipped with either 2, 4,6, 8, or 10 low-pressure 2537 Å Hg lamps.
Reference: [1] Arkivoc, 2017, vol. 2017, # 5, p. 216 - 228
  • 10
  • [ 56-45-1 ]
  • [ 50-81-7 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 271-89-6 ]
  • [ 13925-00-3 ]
  • [ 823-82-5 ]
  • [ 13360-65-1 ]
  • [ 1438-94-4 ]
  • [ 96-76-4 ]
  • [ 13360-64-0 ]
  • [ 21835-01-8 ]
Reference: [1] Food Chemistry, 2010, vol. 119, # 1, p. 214 - 219
  • 11
  • [ 56-45-1 ]
  • [ 50-81-7 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 13925-00-3 ]
  • [ 13238-84-1 ]
  • [ 13360-65-1 ]
  • [ 96-76-4 ]
  • [ 55138-63-1 ]
  • [ 13925-03-6 ]
  • [ 13360-64-0 ]
  • [ 15707-34-3 ]
Reference: [1] Food Chemistry, 2010, vol. 119, # 1, p. 214 - 219
  • 12
  • [ 56-45-1 ]
  • [ 50-81-7 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 13925-00-3 ]
  • [ 13238-84-1 ]
  • [ 13360-65-1 ]
  • [ 96-76-4 ]
  • [ 13925-03-6 ]
  • [ 18138-05-1 ]
  • [ 13360-64-0 ]
  • [ 21835-01-8 ]
Reference: [1] Food Chemistry, 2010, vol. 119, # 1, p. 214 - 219
  • 13
  • [ 56-45-1 ]
  • [ 50-81-7 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 13925-00-3 ]
  • [ 13238-84-1 ]
  • [ 13360-65-1 ]
  • [ 96-76-4 ]
  • [ 13925-03-6 ]
  • [ 13360-64-0 ]
  • [ 15707-34-3 ]
  • [ 21835-01-8 ]
Reference: [1] Food Chemistry, 2010, vol. 119, # 1, p. 214 - 219
  • 14
  • [ 72-19-5 ]
  • [ 50-81-7 ]
  • [ 123-32-0 ]
  • [ 13925-00-3 ]
  • [ 13238-84-1 ]
  • [ 13360-65-1 ]
  • [ 13925-03-6 ]
  • [ 18138-05-1 ]
  • [ 13360-64-0 ]
  • [ 15707-34-3 ]
  • [ 15707-23-0 ]
Reference: [1] Food Chemistry, 2010, vol. 119, # 1, p. 214 - 219
  • 15
  • [ 123-84-2 ]
  • [ 290-37-9 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 13925-00-3 ]
  • [ 693-98-1 ]
  • [ 15707-23-0 ]
Reference: [1] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1993, vol. 29, # 11, p. 1308 - 1315[2] Khimiya Geterotsiklicheskikh Soedinenii, 1993, # 11, p. 1516 - 1525
  • 16
  • [ 930-61-0 ]
  • [ 67-66-3 ]
  • [ 123-32-0 ]
  • [ 4994-86-9 ]
  • [ 693-98-1 ]
  • [ 75712-73-1 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980, p. 1431 - 1435
  • 17
  • [ 930-61-0 ]
  • [ 67-66-3 ]
  • [ 14331-54-5 ]
  • [ 123-32-0 ]
  • [ 54198-89-9 ]
  • [ 4472-45-1 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980, p. 1431 - 1435
  • 18
  • [ 56-87-1 ]
  • [ 50-99-7 ]
  • [ 290-37-9 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 22047-25-2 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 13925-07-0 ]
  • [ 13360-64-0 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 19
  • [ 56-45-1 ]
  • [ 56-87-1 ]
  • [ 50-99-7 ]
  • [ 290-37-9 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 22047-25-2 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 13925-03-6 ]
  • [ 13360-64-0 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 20
  • [ 107-15-3 ]
  • [ 56-81-5 ]
  • [ 290-37-9 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 6705-33-5 ]
  • [ 108-50-9 ]
  • [ 5780-66-5 ]
Reference: [1] Kinetics and Catalysis, 2016, vol. 57, # 5, p. 602 - 609[2] Kinet. Katal., 2016, vol. 57, # 5, p. 607 - 614,8
  • 21
  • [ 930-61-0 ]
  • [ 67-66-3 ]
  • [ 14331-54-5 ]
  • [ 123-32-0 ]
  • [ 54198-89-9 ]
  • [ 4472-45-1 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980, p. 1431 - 1435
  • 22
  • [ 930-61-0 ]
  • [ 67-66-3 ]
  • [ 14331-54-5 ]
  • [ 123-32-0 ]
  • [ 4472-45-1 ]
  • [ 108-50-9 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980, p. 1431 - 1435
  • 23
  • [ 123-32-0 ]
  • [ 98-97-5 ]
  • [ 5521-55-1 ]
  • [ 122-05-4 ]
Reference: [1] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995, vol. 31, # 1, p. 80 - 85[2] Khimiya Geterotsiklicheskikh Soedinenii, 1995, # 1, p. 90 - 96
[3] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995, vol. 31, # 1, p. 80 - 85[4] Khimiya Geterotsiklicheskikh Soedinenii, 1995, # 1, p. 90 - 96
[5] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995, vol. 31, # 1, p. 80 - 85[6] Khimiya Geterotsiklicheskikh Soedinenii, 1995, # 1, p. 90 - 96
  • 24
  • [ 123-32-0 ]
  • [ 98-96-4 ]
  • [ 41110-27-4 ]
Reference: [1] Pharmaceutical Chemistry Journal, 1999, vol. 33, # 7, p. 381 - 383
  • 25
  • [ 123-32-0 ]
  • [ 290-37-9 ]
  • [ 98-96-4 ]
  • [ 5521-57-3 ]
  • [ 41110-27-4 ]
Reference: [1] Pharmaceutical Chemistry Journal, 1999, vol. 33, # 7, p. 381 - 383
  • 26
  • [ 123-32-0 ]
  • [ 290-37-9 ]
  • [ 109-08-0 ]
  • [ 98-96-4 ]
  • [ 41110-27-4 ]
Reference: [1] Pharmaceutical Chemistry Journal, 1999, vol. 33, # 7, p. 381 - 383
[2] Pharmaceutical Chemistry Journal, 1999, vol. 33, # 7, p. 381 - 383
[3] Pharmaceutical Chemistry Journal, 1999, vol. 33, # 7, p. 381 - 383
  • 27
  • [ 123-32-0 ]
  • [ 95-89-6 ]
Reference: [1] Journal of the Chemical Society, 1947, p. 1183
[2] Organic Letters, 2012, vol. 14, # 10, p. 2576 - 2578
[3] Tetrahedron, 2017, vol. 73, # 32, p. 4766 - 4769
  • 28
  • [ 930-61-0 ]
  • [ 67-66-3 ]
  • [ 14331-54-5 ]
  • [ 123-32-0 ]
  • [ 95-89-6 ]
  • [ 38557-72-1 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980, p. 1431 - 1435
  • 29
  • [ 930-61-0 ]
  • [ 67-66-3 ]
  • [ 123-32-0 ]
  • [ 95-89-6 ]
  • [ 38557-72-1 ]
  • [ 75712-74-2 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980, p. 1431 - 1435
  • 30
  • [ 123-32-0 ]
  • [ 13134-38-8 ]
YieldReaction ConditionsOperation in experiment
10% With sodium amide In <i>N</i>,<i>N</i>-dimethyl-aniline at 170℃; for 1 h; (b)
3,6-Dimethylpyrazin-2-amine
A mixture of 2,5-dimethylpyrazine (14 g, 0.13 mol) in N,N-dimethylaniline (50 mL) was heated to 170° C. and NaNH2 (22 g, 0.56 mol) was added in portions.
The reaction mixture was stirred at 170° C. for 1 h, and the solvent was removed.
The product was purified by silica gel column chromatography to give 3,6-dimethylpyrazin-2-amine as a brown solid (1.6 g, yield 10percent). ESI MS: m/z 124 [M+1]+.
Reference: [1] Patent: US2012/178748, 2012, A1, . Location in patent: Page/Page column 41
[2] Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1930, vol. 62, p. 1189,1193[3] Chem. Zentralbl., 1930, vol. 101, # II, p. 3771
[4] Journal of the American Chemical Society, 1941, vol. 63, p. 1929
[5] Journal of the Chemical Society, 1947, p. 371
[6] Patent: WO2011/150156, 2011, A2, . Location in patent: Page/Page column 122
  • 31
  • [ 930-61-0 ]
  • [ 67-66-3 ]
  • [ 14331-54-5 ]
  • [ 123-32-0 ]
  • [ 95-89-6 ]
  • [ 38557-72-1 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980, p. 1431 - 1435
  • 32
  • [ 930-61-0 ]
  • [ 67-66-3 ]
  • [ 123-32-0 ]
  • [ 95-89-6 ]
  • [ 38557-72-1 ]
  • [ 75712-74-2 ]
Reference: [1] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980, p. 1431 - 1435
  • 33
  • [ 123-32-0 ]
  • [ 61892-95-3 ]
Reference: [1] Organic Preparations and Procedures International, 1991, vol. 23, # 2, p. 188 - 190
[2] Synthesis, 1990, # 3, p. 207 - 208
[3] Journal of Organic Chemistry, 1958, vol. 23, p. 1603,1605
  • 34
  • [ 78-90-0 ]
  • [ 56-81-5 ]
  • [ 123-32-0 ]
  • [ 61892-95-3 ]
  • [ 108-50-9 ]
  • [ 77164-93-3 ]
Reference: [1] Chinese Chemical Letters, 2013, vol. 24, # 8, p. 751 - 754
  • 35
  • [ 123-32-0 ]
  • [ 5521-55-1 ]
YieldReaction ConditionsOperation in experiment
81.6% With potassium permanganate In water at 76 - 82℃; for 5.7 h; Industrial scale In a 500-L reactor equipped with a reflux condenser, 250 kg of water and 20 kg of 2,5-dimethylpyrazine were added.Potassium permanganate 4.0kg, heated to 82°C, kept at 80°C for 1.6h, the solution purple faded and cooled to 76°C,Then add 4.0kg of potassium permanganate, slowly warming to 82°C, and hold at 82°C for 1.6h.The solution purple faded and then incubated for 2.5 hours, and the temperature was reduced to 22 DEG C.; the filter cake was filtered, the filter cake was washed with 12 kg of water, and the filtrate was combined;The combined filtrate is first concentrated under normal pressure, distilled out of water and pyrazine solution (recovery application), after about 82percent steaming,Diverted under reduced pressure to dryness; which distilled out of the filtrate 250kg, containing 2,5-dimethyl pyrazine 17kg;Add 15kg of water to the steamed kettle and raise the temperature to 52°C to fully dissolve it; then pump it to a neutralization kettle., Adjust the pH to 2.5 with 1+1 sulfuric acid at about 6Kg, and extract with butanone (80Kg x 3) 3 times at 52 °C to combine the organic phases;The organic phase was allowed to stand for 24 hours and a small amount of water was removed in the lower layer. The upper organic layer was degassed to dryness at atmospheric pressure.Add 10kg of water to heat and dissolve it, and while it is hot, the filtrate is cooled to 0°C, crystallized, and suction filtered.The crude product was dried to 3.6kg; recrystallized from butanone to give 3.2kg of light yellow crystalline powder of 5-methylpyrazine-3-carboxylic acid.The yield was 81.6percent and the purity was 99.4percent.
69.7% at 210 - 220℃; Autoclave; Inert atmosphere In a constant pressure fixed bed reactor1.0 L of the catalyst prepared in Example 1 was used, and the temperature was raised to 210 to 220 ° C under N2 protection. Into a fixed bed reactor at a flow rate of 1.2 L / h, 20 molpercent of 2,5-dimethylpyrazine The aqueous solution (i.e., 2,5-dimethylpyrazine was diluted with water, the amount of water used was 2,5-dimethylpyrazine and 80percent of the total mass of water) and atmospheric pressure at a flow rate of 500 L / h was subjected to catalytic oxidation To obtain a reaction solution. The reaction solution was concentrated to 40percent of the original volume, cooled to 10 to 20 ° C with ice water, adjusted to pH 3 with hydrochloric acid and cooled to 5 ° C to precipitate a light brown product and filtered to give 5-methylpyrazine Carboxylic acid in a yield of 69.7percent.
Reference: [1] Angewandte Chemie, 1992, vol. 104, # 6, p. 748 - 749
[2] Patent: CN108017586, 2018, A, . Location in patent: Paragraph 0016; 0022-0025
[3] Patent: CN103787990, 2016, B, . Location in patent: Paragraph 0035; 0036
[4] Organic Preparations and Procedures International, 1991, vol. 23, # 2, p. 188 - 190
[5] Synthesis, 1990, # 3, p. 207 - 208
[6] Synthesis, 1990, # 3, p. 207 - 208
[7] Synthesis, 1990, # 3, p. 207 - 208
[8] International Journal of Molecular Sciences, 2018, vol. 19, # 10,
  • 36
  • [ 123-32-0 ]
  • [ 5521-55-1 ]
  • [ 122-05-4 ]
Reference: [1] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995, vol. 31, # 1, p. 80 - 85[2] Khimiya Geterotsiklicheskikh Soedinenii, 1995, # 1, p. 90 - 96
  • 37
  • [ 123-32-0 ]
  • [ 5521-55-1 ]
  • [ 103150-78-3 ]
Reference: [1] Journal fuer Praktische Chemie (Leipzig), 1893, vol. &lt;2&gt; 47, p. 494,506, 508[2] Journal fuer Praktische Chemie (Leipzig), 1897, vol. 55, p. 51
[3] Journal fuer Praktische Chemie (Leipzig), 1895, vol. &lt;2&gt;51, p. 464
  • 38
  • [ 123-32-0 ]
  • [ 98-97-5 ]
  • [ 5521-55-1 ]
  • [ 122-05-4 ]
Reference: [1] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995, vol. 31, # 1, p. 80 - 85[2] Khimiya Geterotsiklicheskikh Soedinenii, 1995, # 1, p. 90 - 96
[3] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995, vol. 31, # 1, p. 80 - 85[4] Khimiya Geterotsiklicheskikh Soedinenii, 1995, # 1, p. 90 - 96
[5] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995, vol. 31, # 1, p. 80 - 85[6] Khimiya Geterotsiklicheskikh Soedinenii, 1995, # 1, p. 90 - 96
  • 39
  • [ 103404-72-4 ]
  • [ 78-98-8 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 17398-16-2 ]
  • [ 13925-07-0 ]
  • [ 15707-34-3 ]
  • [ 18433-97-1 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 40
  • [ 106325-92-2 ]
  • [ 78-98-8 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 17398-16-2 ]
  • [ 13925-07-0 ]
  • [ 22047-26-3 ]
  • [ 22047-27-4 ]
  • [ 15707-34-3 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 41
  • [ 56-87-1 ]
  • [ 56-86-0 ]
  • [ 78-98-8 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 108-50-9 ]
  • [ 55138-72-2 ]
  • [ 55138-74-4 ]
  • [ 14667-55-1 ]
  • [ 17398-16-2 ]
  • [ 22047-27-4 ]
  • [ 15707-34-3 ]
  • [ 18433-97-1 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 42
  • [ 56-87-1 ]
  • [ 63-91-2 ]
  • [ 78-98-8 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 55138-72-2 ]
  • [ 14667-55-1 ]
  • [ 17398-16-2 ]
  • [ 13925-07-0 ]
  • [ 15707-34-3 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 43
  • [ 107-15-3 ]
  • [ 56-81-5 ]
  • [ 290-37-9 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 6705-33-5 ]
  • [ 108-50-9 ]
  • [ 5780-66-5 ]
Reference: [1] Kinetics and Catalysis, 2016, vol. 57, # 5, p. 602 - 609[2] Kinet. Katal., 2016, vol. 57, # 5, p. 607 - 614,8
  • 44
  • [ 107-15-3 ]
  • [ 56-81-5 ]
  • [ 290-37-9 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 5780-66-5 ]
Reference: [1] Catalysis Communications, 2011, vol. 12, # 12, p. 1067 - 1070
  • 45
  • [ 123-32-0 ]
  • [ 77666-94-5 ]
  • [ 50866-30-3 ]
  • [ 5780-66-5 ]
Reference: [1] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1986, vol. 22, # 8, p. 915 - 917[2] Khimiya Geterotsiklicheskikh Soedinenii, 1986, # 8, p. 1124 - 1126
[3] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1986, vol. 22, # 8, p. 915 - 917[4] Khimiya Geterotsiklicheskikh Soedinenii, 1986, # 8, p. 1124 - 1126
  • 46
  • [ 56-87-1 ]
  • [ 78-98-8 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 55138-72-2 ]
  • [ 55138-74-4 ]
  • [ 14667-55-1 ]
  • [ 13925-07-0 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 47
  • [ 134276-45-2 ]
  • [ 78-98-8 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 55138-74-4 ]
  • [ 14667-55-1 ]
  • [ 80935-98-4 ]
  • [ 13925-07-0 ]
  • [ 15707-34-3 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 48
  • [ 410538-35-1 ]
  • [ 78-98-8 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 1124-11-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 80935-98-4 ]
  • [ 13925-07-0 ]
  • [ 15707-34-3 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 49
  • [ 50-99-7 ]
  • [ 103404-72-4 ]
  • [ 290-37-9 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 13925-03-6 ]
  • [ 13925-07-0 ]
  • [ 13360-64-0 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 50
  • [ 103404-72-4 ]
  • [ 78-98-8 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 17398-16-2 ]
  • [ 13925-07-0 ]
  • [ 15707-34-3 ]
  • [ 18433-97-1 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 51
  • [ 50-99-7 ]
  • [ 275366-32-0 ]
  • [ 290-37-9 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 13925-03-6 ]
  • [ 13925-07-0 ]
  • [ 13360-64-0 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 52
  • [ 275366-32-0 ]
  • [ 78-98-8 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 80935-98-4 ]
  • [ 13925-07-0 ]
  • [ 22047-27-4 ]
  • [ 15707-34-3 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 53
  • [ 106325-92-2 ]
  • [ 78-98-8 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 17398-16-2 ]
  • [ 13925-07-0 ]
  • [ 22047-26-3 ]
  • [ 22047-27-4 ]
  • [ 15707-34-3 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 54
  • [ 61-90-5 ]
  • [ 56-87-1 ]
  • [ 78-98-8 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 1124-11-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 55138-72-2 ]
  • [ 14667-55-1 ]
  • [ 13925-07-0 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 55
  • [ 56-87-1 ]
  • [ 50-99-7 ]
  • [ 290-37-9 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 22047-25-2 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 13925-07-0 ]
  • [ 13360-64-0 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 56
  • [ 50-99-7 ]
  • [ 45234-02-4 ]
  • [ 290-37-9 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 13925-07-0 ]
  • [ 13360-64-0 ]
  • [ 15707-34-3 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 57
  • [ 50-99-7 ]
  • [ 40719-58-2 ]
  • [ 290-37-9 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 13925-03-6 ]
  • [ 13925-07-0 ]
  • [ 13360-64-0 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 58
  • [ 40719-58-2 ]
  • [ 78-98-8 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 80935-98-4 ]
  • [ 13925-07-0 ]
  • [ 22047-26-3 ]
  • [ 15707-34-3 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 59
  • [ 78-98-8 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 1124-11-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 80935-98-4 ]
  • [ 13925-07-0 ]
  • [ 15707-34-3 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 60
  • [ 56-41-7 ]
  • [ 56-87-1 ]
  • [ 78-98-8 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 80935-98-4 ]
  • [ 13925-07-0 ]
  • [ 22047-26-3 ]
  • [ 15707-34-3 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 61
  • [ 56-87-1 ]
  • [ 56-86-0 ]
  • [ 50-99-7 ]
  • [ 290-37-9 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 13925-03-6 ]
  • [ 13925-07-0 ]
  • [ 13360-64-0 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 62
  • [ 56-87-1 ]
  • [ 63-91-2 ]
  • [ 78-98-8 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 55138-72-2 ]
  • [ 14667-55-1 ]
  • [ 17398-16-2 ]
  • [ 13925-07-0 ]
  • [ 15707-34-3 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 63
  • [ 56-87-1 ]
  • [ 56-40-6 ]
  • [ 78-98-8 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 5910-89-4 ]
  • [ 1124-11-4 ]
  • [ 13360-65-1 ]
  • [ 108-50-9 ]
  • [ 14667-55-1 ]
  • [ 13925-07-0 ]
  • [ 22047-26-3 ]
  • [ 15707-34-3 ]
Reference: [1] Journal of Agricultural and Food Chemistry, 2010, vol. 58, # 4, p. 2470 - 2478
  • 64
  • [ 78-90-0 ]
  • [ 56-81-5 ]
  • [ 123-32-0 ]
  • [ 108-50-9 ]
  • [ 77164-93-3 ]
Reference: [1] Chinese Chemical Letters, 2013, vol. 24, # 8, p. 751 - 754
  • 65
  • [ 78-90-0 ]
  • [ 56-81-5 ]
  • [ 123-32-0 ]
  • [ 61892-95-3 ]
  • [ 108-50-9 ]
  • [ 77164-93-3 ]
Reference: [1] Chinese Chemical Letters, 2013, vol. 24, # 8, p. 751 - 754
  • 66
  • [ 123-32-0 ]
  • [ 41110-33-2 ]
Reference: [1] Journal of Organic Chemistry, 2007, vol. 72, # 19, p. 7294 - 7300
[2] Journal of Organic Chemistry, 2007, vol. 72, # 19, p. 7294 - 7300
  • 67
  • [ 72-19-5 ]
  • [ 50-81-7 ]
  • [ 123-32-0 ]
  • [ 13925-00-3 ]
  • [ 13238-84-1 ]
  • [ 13360-65-1 ]
  • [ 13925-03-6 ]
  • [ 18138-05-1 ]
  • [ 13360-64-0 ]
  • [ 15707-34-3 ]
  • [ 15707-23-0 ]
  • [ 18138-04-0 ]
Reference: [1] Food Chemistry, 2010, vol. 119, # 1, p. 214 - 219
  • 68
  • [ 123-84-2 ]
  • [ 290-37-9 ]
  • [ 109-08-0 ]
  • [ 123-32-0 ]
  • [ 13925-00-3 ]
  • [ 693-98-1 ]
  • [ 15707-23-0 ]
Reference: [1] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1993, vol. 29, # 11, p. 1308 - 1315[2] Khimiya Geterotsiklicheskikh Soedinenii, 1993, # 11, p. 1516 - 1525
  • 69
  • [ 57-55-6 ]
  • [ 123-32-0 ]
  • [ 6168-72-5 ]
  • [ 14008-30-1 ]
  • [ 78-90-0 ]
  • [ 108-49-6 ]
Reference: [1] Patent: CN104693038, 2017, B, . Location in patent: Paragraph 0052-0053; 0089
[2] Patent: CN104693038, 2017, B, . Location in patent: Paragraph 0056-0057; 0089
[3] Patent: CN104693038, 2017, B, . Location in patent: Paragraph 0058-0059; 0089
[4] Patent: CN104693038, 2017, B, . Location in patent: Paragraph 0060-0061; 0089
[5] Patent: CN104693038, 2017, B, . Location in patent: Paragraph 0076-0077; 0089
  • 70
  • [ 123-32-0 ]
  • [ 128229-06-1 ]
Reference: [1] Synthesis, 1990, # 3, p. 207 - 208