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Quality Control of Fmoc-Nle-OH Purity: 97% SDS Specification

COA

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NMR

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Product Details of Fmoc-Nle-OH

CAS No. :	77284-32-3
Formula :	C₂₁H₂₃NO₄
M.W :	353.41
SMILES Code :	CCCC[C@@H](C(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C13)=O
Synonyms :	Fmoc-L-Norleucine
MDL No. :	MFCD00037537
InChI Key :	VCFCFPNRQDANPN-IBGZPJMESA-N
Pubchem ID :	7009636

Safety of Fmoc-Nle-OH

GHS Pictogram:
Signal Word:	Warning
Hazard Statements:	H315-H319-H335
Precautionary Statements:	P261-P305+P351+P338

Application In Synthesis of Fmoc-Nle-OH

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 77284-32-3 ]

[ 77284-32-3 ] Synthesis Path-Downstream 1~26

1
[ 29022-11-5 ]
[ 35737-15-6 ]
[ 77128-73-5 ]
[ 77284-32-3 ]
Fmoc-D-Asp(t-Bu)-OH, Hpa-OSu [ No CAS ]
(R)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-{(S)-2-[(S)-2-(2-{(S)-2-[2-(4-hydroxy-phenyl)-acetylamino]-hexanoylamino}-acetylamino)-3-(1H-indol-3-yl)-propionylamino]-hexanoylamino}-N-methyl-succinamic acid [ No CAS ]

References: [1]Journal of Medicinal Chemistry,1997,vol. 40,p. 4302 - 4307.

2
[ 67-56-1 ]
[ 122889-11-6 ]
[ 77284-32-3 ]
[ 708-06-5 ]
Gly-Wang resin [ No CAS ]
[(S)-2-((S)-3-Benzyloxy-2-[1-(2-hydroxy-naphthalen-1-yl)-meth-(E)-ylidene]-amino}-propionylamino)-hexanoylamino]-acetic acid methyl ester [ No CAS ]

References: [1]Journal of the American Chemical Society,2004,vol. 126,p. 10676 - 10681.

3
[ 67-56-1 ]
[ 96402-49-2 ]
[ 77284-32-3 ]
[ 708-06-5 ]
Gly-Wang resin [ No CAS ]
[(S)-2-((S)-2-[1-(2-Hydroxy-naphthalen-1-yl)-meth-(E)-ylidene]-amino}-3-naphthalen-1-yl-propionylamino)-hexanoylamino]-acetic acid methyl ester [ No CAS ]

References: [1]Journal of the American Chemical Society,2004,vol. 126,p. 10676 - 10681.

4
[ 67-56-1 ]
[ 139090-50-9 ]
[ 77284-32-3 ]
[ 708-06-5 ]
Gly-Wang resin [ No CAS ]
C₃₃H₄₂N₆O₇S [ No CAS ]

References: [1]Journal of the American Chemical Society,2004,vol. 126,p. 10676 - 10681.

5
[ 71989-18-9 ]
[ 132684-59-4 ]
[ 77284-32-3 ]
[ 135112-28-6 ]
[ 125238-99-5 ]
N-(9-fluorenylmethoxycarbonyl)-3-(β-naphthyl)-L-alanine [ No CAS ]
[ 1349220-85-4 ]

References: [1]Bioorganic and Medicinal Chemistry,2009,vol. 17,p. 5229 - 5237.

6
[ 159610-89-6 ]
[ 68858-20-8 ]
[ 71989-38-3 ]
[ 71989-26-9 ]
[ 77284-32-3 ]
[ 94744-50-0 ]
N,N'-bis(tert-butyloxycarbonyl)-L-lysine dicyclohexylamine salt [ No CAS ]
[ 198561-07-8 ]
[ 1443329-49-4 ]

References: [1]Journal of Peptide Science,2013,vol. 19,p. 423 - 432.

7
[ 159610-89-6 ]
[ 108-24-7 ]
[ 86123-10-6 ]
[ 109425-51-6 ]
[ 77284-32-3 ]
[ 143824-78-6 ]
Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine [ No CAS ]
[ 198561-07-8 ]
Ac-Nle-Pra-His-D-Phe-Arg-Trp-Nle(ε-N_3)-NH2 [ No CAS ]

References: [1]Journal of Medicinal Chemistry,2014,vol. 57,p. 9424 - 9434.

8
[ 159610-89-6 ]
[ 108-24-7 ]
[ 86123-10-6 ]
[ 109425-51-6 ]
[ 77284-32-3 ]
[ 143824-78-6 ]
Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine [ No CAS ]
[ 198561-07-8 ]
Ac-Nle-Nle(N3)-His-D-Phe-Arg-Trp-Pra-NH2 [ No CAS ]

References: [1]Journal of Medicinal Chemistry,2014,vol. 57,p. 9424 - 9434.

9
[ 56-45-1 ]
[ 29022-11-5 ]
[ 35661-60-0 ]
C₂₂H₂₆N₂O₃ [ No CAS ]
[ 71989-31-6 ]
[ 135944-05-7 ]
[ 91000-69-0 ]
[ 77284-32-3 ]
[ 109425-56-1 ]
[ 116611-64-4 ]
PyrRPRLSHKGPNleP(α-Me)Phe [ No CAS ]

References: [1]Journal of Medicinal Chemistry,2015,vol. 58,p. 2431 - 2440.

10
(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-methylhept-6-enoic acid [ No CAS ]
[ 29022-11-5 ]
[ 68858-20-8 ]
[ 1311933-83-1 ]
[ 71989-31-6 ]
[ 71989-33-8 ]
[ 71989-18-9 ]
[ 71989-23-6 ]
[ 71989-26-9 ]
[ 132327-80-1 ]
[ 77284-32-3 ]
C₁₂₂H₁₇₉N₁₆O₂₂Pol [ No CAS ]

References: [1]RSC Advances,2015,vol. 5,p. 55784 - 55794.

11
[ 35661-60-0 ]
[ 35661-39-3 ]
Boc-His(Trt)-Gly-Asp(tBu)-Gly-OH [ No CAS ]
[ 35661-40-6 ]
[ 71989-14-5 ]
[ 71989-23-6 ]
[ 71989-26-9 ]
[ 132388-59-1 ]
[ 132327-80-1 ]
[ 77284-32-3 ]
[ 104091-08-9 ]
[ 143824-78-6 ]
Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine [ No CAS ]
Fmoc-Thr(Pg)-OH [ No CAS ]
Fmoc-Ser(Pg)-OH [ No CAS ]
C₁₅₁H₂₃₂N₄₂O₄₈ [ No CAS ]

References: [1]Journal of Medicinal Chemistry,2016,vol. 59,p. 3129 - 3139.

12
[ 35661-60-0 ]
[ 35661-39-3 ]
Boc-His(Trt)-Gly-Asp(tBu)-Gly-OH [ No CAS ]
[ 35661-40-6 ]
[ 71989-14-5 ]
[ 71989-18-9 ]
[ 71989-23-6 ]
[ 71989-26-9 ]
[ 132388-59-1 ]
[ 132327-80-1 ]
[ 96402-49-2 ]
[ 77284-32-3 ]
[ 143824-78-6 ]
Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine [ No CAS ]
Fmoc-Thr(Pg)-OH [ No CAS ]
Fmoc-Ser(Pg)-OH [ No CAS ]
C₁₆₀H₂₃₇N₄₁O₄₇ [ No CAS ]

References: [1]Journal of Medicinal Chemistry,2016,vol. 59,p. 3129 - 3139.

13
[ 35661-60-0 ]
[ 35661-39-3 ]
Boc-His(Trt)-Gly-Asp(tBu)-Gly-OH [ No CAS ]
[ 35661-40-6 ]
[ 71989-14-5 ]
[ 71989-18-9 ]
[ 71989-23-6 ]
[ 71989-26-9 ]
[ 132388-59-1 ]
[ 132327-80-1 ]
[ 77284-32-3 ]
[ 32926-43-5 ]
[ 143824-78-6 ]
Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine [ No CAS ]
Fmoc-Thr(Pg)-OH [ No CAS ]
Fmoc-Ser(Pg)-OH [ No CAS ]
C₁₅₃H₂₃₃N₄₃O₄₇ [ No CAS ]

References: [1]Journal of Medicinal Chemistry,2016,vol. 59,p. 3129 - 3139.

14
[ 35661-60-0 ]
[ 35661-39-3 ]
Boc-His(Trt)-Gly-Asp(tBu)-Gly-OH [ No CAS ]
[ 35661-40-6 ]
[ 71989-14-5 ]
[ 71989-18-9 ]
[ 71989-23-6 ]
[ 71989-26-9 ]
[ 132388-59-1 ]
[ 132327-80-1 ]
[ 77284-32-3 ]
[ 32926-43-5 ]
[ 143824-78-6 ]
Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine [ No CAS ]
Fmoc-Thr(Pg)-OH [ No CAS ]
Fmoc-Ser(Pg)-OH [ No CAS ]
C₁₅₃H₂₃₃N₄₃O₄₇ [ No CAS ]

References: [1]Journal of Medicinal Chemistry,2016,vol. 59,p. 3129 - 3139.

15
[ 35661-60-0 ]
[ 35661-39-3 ]
[ 35661-40-6 ]
[ 71989-14-5 ]
[ 71989-18-9 ]
[ 71989-23-6 ]
[ 71989-26-9 ]
[ 35661-38-2 ]
[ 132388-59-1 ]
[ 132327-80-1 ]
[ 77284-32-3 ]
[ 32926-43-5 ]
[ 143824-78-6 ]
Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine [ No CAS ]
Fmoc-Thr(Pg)-OH [ No CAS ]
Fmoc-Ser(Pg)-OH [ No CAS ]
C₁₅₂H₂₃₄N₄₂O₄₈ [ No CAS ]

References: [1]Journal of Medicinal Chemistry,2016,vol. 59,p. 3129 - 3139.

16
[ 29022-11-5 ]
[ 35661-39-3 ]
[ 35661-40-6 ]
[ 71989-14-5 ]
[ 71989-38-3 ]
[ 77284-32-3 ]
[ 104091-08-9 ]
[ 143824-78-6 ]
[ 137076-54-1 ]
DOTA-DGlu-Ala-Tyr-Gly-Trp-Nle-Asp-Phe-NH2, Nle=norleucine, DOTA=1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid [ No CAS ]

References: [1]Journal of Peptide Science,2017,vol. 23,p. 38 - 44.

17
[ 35661-39-3 ]
[ 35661-38-2 ]
[ 77284-32-3 ]
[ 71989-31-6 ]
[ 135112-28-6 ]
[ 143674-78-6 ]
[ 170642-27-0 ]
[ 112883-41-7 ]
C₆₂H₈₄N₉O₁₃Pol [ No CAS ]